The G Protein–Gated Potassium Current IK,ACh Is Constitutively Active in Patients With Chronic Atrial Fibrillation D Dobrev, A Friedrich, N Voigt, N Jost, E Wettwer, T Christ, M Knaut, ... Circulation 112 (24), 3697-3706, 2005 | 589 | 2005 |
Molecular basis of downregulation of G-protein–coupled inward rectifying K+ current (IK, ACh) in chronic human atrial fibrillation: Decrease in GIRK4 mRNA correlates with … D Dobrev, E Graf, E Wettwer, HM Himmel, O Hala, C Doerfel, T Christ, ... Circulation 104 (21), 2551-2557, 2001 | 405 | 2001 |
Human engineered heart tissue: analysis of contractile force I Mannhardt, K Breckwoldt, D Letuffe-Brenière, S Schaaf, H Schulz, ... Stem cell reports 7 (1), 29-42, 2016 | 385 | 2016 |
L-Type Ca2+ Current Downregulation in Chronic Human Atrial Fibrillation Is Associated With Increased Activity of Protein Phosphatases T Christ, P Boknik, S Wohrl, E Wettwer, EM Graf, RF Bosch, M Knaut, ... Circulation 110 (17), 2651-2657, 2004 | 365 | 2004 |
Human Atrial Ion Channel and Transporter Subunit Gene-Expression Remodeling Associated With Valvular Heart Disease and Atrial Fibrillation N Gaborit, M Steenman, G Lamirault, N Le Meur, S Le Bouter, G Lande, ... Circulation 112 (4), 471-481, 2005 | 349 | 2005 |
Role of IKur in Controlling Action Potential Shape and Contractility in the Human Atrium: Influence of Chronic Atrial Fibrillation E Wettwer, O Hála, T Christ, JF Heubach, D Dobrev, M Knaut, A Varró, ... Circulation 110 (16), 2299-2306, 2004 | 341 | 2004 |
Electrophysiological properties of human mesenchymal stem cells JF Heubach, EM Graf, J Leutheuser, M Bock, B Balana, I Zahanich, ... The Journal of physiology 554 (3), 659-672, 2004 | 284 | 2004 |
Adult zebrafish heart as a model for human heart? An electrophysiological study P Nemtsas, E Wettwer, T Christ, G Weidinger, U Ravens Journal of molecular and cellular cardiology 48 (1), 161-171, 2010 | 235 | 2010 |
Adipocyte fatty acid–binding protein suppresses cardiomyocyte contraction: a new link between obesity and heart disease V Lamounier-Zepter, C Look, J Alvarez, T Christ, U Ravens, WH Schunck, ... Circulation research 105 (4), 326-334, 2009 | 207 | 2009 |
Human iPSC-derived cardiomyocytes cultured in 3D engineered heart tissue show physiological upstroke velocity and sodium current density MD Lemoine, I Mannhardt, K Breckwoldt, M Prondzynski, F Flenner, ... Scientific reports 7 (1), 5464, 2017 | 204 | 2017 |
Small-conductance calcium-activated potassium (SK) channels contribute to action potential repolarization in human atria L Skibsbye, C Poulet, JG Diness, BH Bentzen, L Yuan, U Kappert, ... Cardiovascular research 103 (1), 156-167, 2014 | 202 | 2014 |
Differential phosphorylation-dependent regulation of constitutively active and muscarinic receptor-activated IK,ACh channels in patients with chronic atrial fibrillation N Voigt, A Friedrich, M Bock, E Wettwer, T Christ, M Knaut, RH Strasser, ... Cardiovascular research 74 (3), 426-437, 2007 | 161 | 2007 |
Activation of human ether-a-go-go-related gene potassium channels by the diphenylurea 1, 3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643) RS Hansen, TG Diness, T Christ, J Demnitz, U Ravens, SP Olesen, ... Molecular Pharmacology 69 (1), 266-277, 2006 | 153 | 2006 |
Atrial-like engineered heart tissue: an in vitro model of the human atrium M Lemme, BM Ulmer, MD Lemoine, ATL Zech, F Flenner, U Ravens, ... Stem cell reports 11 (6), 1378-1390, 2018 | 145 | 2018 |
Pathology-specific effects of the IKur/Ito/IK, ACh blocker AVE0118 on ion channels in human chronic atrial fibrillation T Christ, E Wettwer, N Voigt, O Hala, S Radicke, K Matschke, A Varro, ... British journal of pharmacology 154 (8), 1619, 2008 | 144 | 2008 |
Autoantibodies Against the β1adrenoceptor from Patients with Dilated Cardiomyopathy Prolong Action Potential Duration and Enhance Contractility in Isolated Cardiomyocytes T Christ, E Wettwer, D Dobrev, E Adolph, M Knaut, G Wallukat, U Ravens Journal of molecular and cellular cardiology 33 (8), 1515-1525, 2001 | 142 | 2001 |
5-Azacytidine induces changes in electrophysiological properties of human mesenchymal stem cells B Balana, C Nicoletti, I Zahanich, EM Graf, T Christ, S Boxberger, ... Cell Research 16 (12), 949-960, 2006 | 135 | 2006 |
The new antiarrhythmic drug vernakalant: ex vivo study of human atrial tissue from sinus rhythm and chronic atrial fibrillation E Wettwer, T Christ, S Endig, N Rozmaritsa, K Matschke, JJ Lynch, ... Cardiovascular research 98 (1), 145-154, 2013 | 120 | 2013 |
Disease modeling of a mutation in α‐actinin 2 guides clinical therapy in hypertrophic cardiomyopathy M Prondzynski, MD Lemoine, ATL Zech, A Horváth, V Di Mauro, ... EMBO Molecular Medicine 11 (12), e11115, 2019 | 109 | 2019 |
Transmural expression of ion channels and transporters in human nondiseased and end-stage failing hearts E Soltysinska, SP Olesen, T Christ, E Wettwer, A Varró, M Grunnet, ... Pflügers Archiv-European Journal of Physiology 459, 11-23, 2009 | 107 | 2009 |