| Toll-like receptor 2 ligands on the staphylococcal cell wall downregulate superantigen-induced T cell activation and prevent toxic shock syndrome TA Chau, ML McCully, W Brintnell, G An, KJ Kasper, ED Vinés, P Kubes, ... Nature medicine 15 (6), 641-648, 2009 | 170 | 2009 |
| Bacterial Superantigens Promote Acute Nasopharyngeal Infection by Streptococcus pyogenes in a Human MHC Class II-Dependent Manner KJ Kasper, JJ Zeppa, AT Wakabayashi, SX Xu, DM Mazzuca, I Welch, ... PLoS pathogens 10 (5), e1004155, 2014 | 116 | 2014 |
| Nasopharyngeal infection by Streptococcus pyogenes requires superantigen-responsive Vβ-specific T cells JJ Zeppa, KJ Kasper, I Mohorovic, DM Mazzuca, SMM Haeryfar, ... Proceedings of the National Academy of Sciences 114 (38), 10226-10231, 2017 | 72 | 2017 |
| A novel loop domain in superantigens extends their T cell receptor recognition site S Günther, AK Varma, B Moza, KJ Kasper, AW Wyatt, P Zhu, ... Journal of molecular biology 371 (1), 210-221, 2007 | 66 | 2007 |
| Prophage exotoxins enhance colonization fitness in epidemic scarlet fever-causing Streptococcus pyogenes S Brouwer, TC Barnett, D Ly, KJ Kasper, DMP De Oliveira, ... Nature communications 11 (1), 5018, 2020 | 59 | 2020 |
| The SaeRS two-component system is a direct and dominant transcriptional activator of toxic shock syndrome toxin 1 in Staphylococcus aureus ML Baroja, CA Herfst, KJ Kasper, SX Xu, DA Gillett, J Li, G Reid, ... Journal of Bacteriology 198 (19), 2732-2742, 2016 | 45 | 2016 |
| Superantigens Modulate Bacterial Density during Staphylococcus aureus Nasal Colonization SX Xu, KJ Kasper, JJ Zeppa, JK McCormick Toxins 7 (5), 1821-1836, 2015 | 41 | 2015 |
| Superantigens promote Staphylococcus aureus bloodstream infection by eliciting pathogenic interferon-gamma production SW Tuffs, MI Goncheva, SX Xu, HC Craig, KJ Kasper, J Choi, ... Proceedings of the National Academy of Sciences 119 (8), e2115987119, 2022 | 38 | 2022 |
| A controlled-release oral opioid supports S. aureus survival in injection drug preparation equipment and may increase bacteremia and endocarditis risk KJ Kasper, I Manoharan, B Hallam, CE Coleman, SL Koivu, MA Weir, ... PloS one 14 (8), e0219777, 2019 | 34 | 2019 |
| Attenuation of massive cytokine response to the staphylococcal enterotoxin B superantigen by the innate immunomodulatory protein lactoferrin JL Hayworth, KJ Kasper, M Leon-Ponte, CA Herfst, D Yue, WC Brintnell, ... Clinical & Experimental Immunology 157 (1), 60-70, 2009 | 34 | 2009 |
| Streptococcal pharyngitis and rheumatic heart disease: the superantigen hypothesis revisited JR Hurst, KJ Kasper, AN Sule, JK McCormick Infection, Genetics and Evolution 61, 160-175, 2018 | 27 | 2018 |
| The T cell receptor β-chain second complementarity determining region loop (CDR2β) governs T cell activation and Vβ specificity by bacterial superantigens AKMN Rahman, DA Bonsor, CA Herfst, F Pollard, M Peirce, AW Wyatt, ... Journal of Biological Chemistry 286 (6), 4871-4881, 2011 | 24 | 2011 |
| Molecular requirements for MHC class II α-chain engagement and allelic discrimination by the bacterial superantigen streptococcal pyrogenic exotoxin C KJ Kasper, W Xi, N Rahman, MM Nooh, M Kotb, EJ Sundberg, ... The Journal of Immunology 181 (5), 3384-3392, 2008 | 21 | 2008 |
| Fournier’s gangrene of the penis caused by Streptococcus dysgalactiae subspecies equisimilis: case report and incidence study in a tertiary-care hospital RV Anantha, KJ Kasper, KG Patterson, JJ Zeppa, J Delport, ... BMC infectious Diseases 13, 1-5, 2013 | 15 | 2013 |
| Nasopharyngeal Infection of Mice with Streptococcus pyogenes and In Vivo Detection of Superantigen Activity JJ Zeppa, AT Wakabayashi, KJ Kasper, SX Xu, SMM Haeryfar, ... Superantigens: Methods and Protocols, 95-107, 2016 | 12 | 2016 |
| Streptolysin S is required for Streptococcus pyogenes nasopharyngeal and skin infection in HLA-transgenic mice BA Shannon, JR Hurst, RS Flannagan, HC Craig, A Rishi, KJ Kasper, ... PLoS pathogens 20 (3), e1012072, 2024 | 3 | 2024 |
| Systematic Assessment of the Contribution of Superantigens to Nasopharyngeal Colonization in a Mouse Model of Streptococcal Infection KJ Kasper The University of Western Ontario (Canada), 2013 | 3 | 2013 |
| Functional Characterization of Streptococcal Superantigen Low-Affinity MHC Class II Binding Interfaces KJ Kasper Faculty of Graduate Studies, University of Western Ontario, 2007 | 2 | 2007 |
| Correction: A controlled-release oral opioid supports S. aureus survival in injection drug preparation equipment and may increase bacteremia and endocarditis risk KJ Kasper, I Manoharan, B Hallam, CE Coleman, SL Koivu, MA Weir, ... Plos one 14 (9), e0223079, 2019 | 1 | 2019 |
| TSST-1 promotes colonization of Staphylococcus aureus within the vaginal tract by activation of CD8+T cells K Dufresne, KF Al, HC Craig, CEM Coleman, KJ Kasper, JP Burton, ... bioRxiv, 2024.10. 04.616698, 2024 | | 2024 |
