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Jonathan Parkinson
Jonathan Parkinson
Bioinformatics scientist at UCSD
在 ucsd.edu 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Discovery of cyclic boronic acid QPX7728, an ultrabroad-spectrum inhibitor of serine and metallo-β-lactamases
SJ Hecker, KR Reddy, O Lomovskaya, DC Griffith, D Rubio-Aparicio, ...
Journal of medicinal chemistry 63 (14), 7491-7507, 2020
1722020
Discrimination of single-point mutations in unamplified genomic DNA via Cas9 immobilized on a graphene field-effect transistor
S Balderston, JJ Taulbee, E Celaya, K Fung, A Jiao, K Smith, R Hajian, ...
Nature Biomedical Engineering 5 (7), 713-725, 2021
1012021
Activity of Simulated Human Dosage Regimens of Meropenem and Vaborbactam against Carbapenem-Resistant Enterobacteriaceae in an In Vitro Hollow-Fiber …
M Sabet, Z Tarazi, D Rubio-Aparicio, TG Nolan, J Parkinson, ...
Antimicrobial agents and chemotherapy 62 (2), 10.1128/aac. 01969-17, 2018
412018
Activity of meropenem-vaborbactam in mouse models of infection due to KPC-producing carbapenem-resistant Enterobacteriaceae
M Sabet, Z Tarazi, T Nolan, J Parkinson, D Rubio-Aparicio, ...
Antimicrobial Agents and Chemotherapy 62 (1), 10.1128/aac. 01446-17, 2018
332018
The promise of graphene-based transistors for democratizing multiomics studies
HW Lu, AA Kane, J Parkinson, Y Gao, R Hajian, M Heltzen, B Goldsmith, ...
Biosensors and Bioelectronics 195, 113605, 2022
322022
Rapid and Electronic Identification and Quantification of Age‐Specific Circulating Exosomes via Biologically Activated Graphene Transistors
R Hajian, J DeCastro, J Parkinson, A Kane, AFR Camelo, PP Chou, ...
Advanced Biology 5 (7), 2000594, 2021
222021
The RESP AI model accelerates the identification of tight-binding antibodies
J Parkinson, R Hard, W Wang
Nature communications 14 (1), 454, 2023
172023
Selection of QPX7831, an orally bioavailable prodrug of boronic acid β-lactamase inhibitor QPX7728
KR Reddy, J Parkinson, M Sabet, Z Tarazi, SH Boyer, O Lomovskaya, ...
Journal of Medicinal Chemistry 64 (23), 17523-17529, 2021
142021
Engineering a histone reader protein by combining directed evolution, sequencing, and neural network based ordinal regression
J Parkinson, R Hard, RI Ainsworth, N Li, W Wang
Journal of Chemical Information and Modeling 60 (8), 3992-4004, 2020
122020
In vivo efficacy of Carbavance (meropenem/RPX7009) against KPC-producing Enterobacteriaceae
M Sabet, Z Tarazi, T Nolan, J Parkinson, D Rubio-Aparicio, ...
54th Interscience Conference on Antimicrobial Agents and Chemotherapy …, 2014
112014
Efficacy of simulated human exposures of Carbavance (meropenem-RPX7009) against carbapenem-resistant Enterobacteriaceae in an in vitro hollow fiber model, abstr F-959
Z Tarazi, M Sabet, D Rubio-Aparicio, T Nolan, J Parkinson, ...
Intersci Conf Antimicrob Agents Chemother, Washington, DC 5, 2014
102014
Linear-Scaling kernels for protein sequences and small molecules outperform deep learning while providing uncertainty quantitation and improved interpretability
J Parkinson, W Wang
Journal of Chemical Information and Modeling 63 (15), 4589-4601, 2023
7*2023
Pharmacology of the novel polymyxin Faddi-287 in preclinical models
M Sabet, Z Tarazi, T Nolan, J Parkinson, D Rubio-Aparicio, KD Roberts, ...
Poster at the Saturday-499. ASM Microbe,(Boston, MA), 2016
72016
Machine learning for disease classification: A perspective
J Parkinson, JH DeCastro, B Goldsmith, K Aran
Artificial Intelligence in Healthcare and Medicine, 1-27, 2022
22022
For antibody sequence generative modeling, mixture models may be all you need
J Parkinson, W Wang
Bioinformatics 40 (5), btae278, 2024
2024
TUnA: An uncertainty aware transformer model for sequence-based protein-protein interaction prediction
YS Ko, J Parkinson, C Liu, W Wang
bioRxiv, 2024.02. 19.581072, 2024
2024
Scalable apparatuses and models for determining analytically efficient transfer curve parameters for sensor ics with 2d field effect transistors
B Goldsmith, J Parkinson, K Aran, A Kane
US Patent App. 18/319,347, 2023
2023
Engineering human JMJD2A tudor domains for an improved understanding of histone peptide recognition
J Parkinson, R Hard, R Ainsworth, W Wang
Proteins: Structure, Function, and Bioinformatics 91 (1), 32-46, 2023
2023
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