Catalytic in vivo protein knockdown by small-molecule PROTACs DP Bondeson, A Mares, IED Smith, E Ko, S Campos, AH Miah, ... Nature chemical biology 11 (8), 611-617, 2015 | 1098 | 2015 |
Lessons in PROTAC design from selective degradation with a promiscuous warhead DP Bondeson, BE Smith, GM Burslem, AD Buhimschi, J Hines, ... Cell chemical biology 25 (1), 78-87. e5, 2018 | 688 | 2018 |
The advantages of targeted protein degradation over inhibition: an RTK case study GM Burslem, BE Smith, AC Lai, S Jaime-Figueroa, DC McQuaid, ... Cell chemical biology 25 (1), 67-77. e3, 2018 | 539 | 2018 |
Targeted protein degradation by small molecules DP Bondeson, CM Crews Annual review of pharmacology and toxicology 57, 107-123, 2017 | 172 | 2017 |
Targeting BCR-ABL1 in chronic myeloid leukemia by PROTAC-mediated targeted protein degradation GM Burslem, AR Schultz, DP Bondeson, CA Eide, SL Savage Stevens, ... Cancer research 79 (18), 4744-4753, 2019 | 166 | 2019 |
In vivo Drosophilia genetic model for calcium oxalate nephrolithiasis T Hirata, P Cabrero, DS Berkholz, DP Bondeson, EL Ritman, ... American Journal of Physiology-Renal Physiology 303 (11), F1555-F1562, 2012 | 64 | 2012 |
Ion and solute transport by Prestin in Drosophila and Anopheles T Hirata, A Czapar, L Brin, A Haritonova, DP Bondeson, P Linser, ... Journal of insect physiology 58 (4), 563-569, 2012 | 34 | 2012 |
Phosphate dysregulation via the XPR1–KIDINS220 protein complex is a therapeutic vulnerability in ovarian cancer DP Bondeson, BR Paolella, A Asfaw, MV Rothberg, TA Skipper, ... Nature cancer 3 (6), 681-695, 2022 | 31 | 2022 |
Scaffold hopping enables direct access to more potent PROTACs with in vivo activity GM Burslem, DP Bondeson, CM Crews Chemical communications 56 (50), 6890-6892, 2020 | 22 | 2020 |
Systematic profiling of conditional degron tag technologies for target validation studies DP Bondeson, Z Mullin-Bernstein, S Oliver, TA Skipper, TC Atack, N Bick, ... Nature communications 13 (1), 5495, 2022 | 16 | 2022 |
An In Vitro Pull-down Assay of the E3 Ligase: PROTAC: Substrate Ternary Complex to Identify Effective PROTACs DP Bondeson, BE Smith, AD Buhimschi Targeted Protein Degradation: Methods and Protocols, 135-150, 2021 | 2 | 2021 |
Therapeutic targeting of phosphate dysregulation in cancer via the xpr1: kidins220 protein complex T Golub, D Bondeson, B Paolella, F Vazquez US Patent App. 18/019,851, 2023 | | 2023 |
Phosphate dysregulation as a novel therapeutic strategy in ovarian and uterine cancers D Bondeson, B Paolella, A Asfaw, M Rothberg, T Skipper, G Mesa, ... Cancer Research 82 (12_Supplement), 1028-1028, 2022 | | 2022 |
In vivo Nanopool: Pooled sgRNA competition assays to evaluate in vivo cancer dependencies T Skipper, D Bondeson, B Paolella, F Vazquez | | 2020 |
Targeted protein degradation as a tool to probe non-kinase roles in myeloid leukemias G Burslem, A Schultz, D Bondeson, J Song, C Eide, S Savage, J Hines, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019 | | 2019 |
Furthering the Scope, Understanding, and Application of Proteolysis Targeting Chimera DP Bondeson Yale University, 2018 | | 2018 |
PROTACs: Potent protein knockdown by hijacking E3 ubiquitin ligases D Bondeson, A Mares, I Smith, E Ko, S Campos, A Miah, K Mulholland, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 250, 2015 | | 2015 |
Small molecule‐induced catalytic ubiquitination of non‐natural substrates D Bondeson, C Pancevac, L Kruidenier, P Carter, I Churcher, C Crews The FASEB Journal 29, 573.43, 2015 | | 2015 |
Real‐time visualization of calcium oxalate crystals in Drosophila‐a gut and renal model of kidney stones DP Bondeson, T Hirata, P Cabrero, EL Ritman, JAT Dow, MF Romero The FASEB Journal 26, 1152.25-1152.25, 2012 | | 2012 |
2070 DEVELOPMENT OF DROSOPHILA KIDNEY STONE MODEL AND REAL-TIME VISUALIZATION OF CALCIUM OXALATE CRYSTAL FORMATION T Hirata, P Cabrero, D Bondeson, D Berkholz, E Ritman, J Thompson, ... The Journal of Urology 187 (4S), e835-e835, 2012 | | 2012 |