| GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand L Yang, CC Chang, Z Sun, D Madsen, H Zhu, SB Padkjær, X Wu, ... Nature medicine 23 (10), 1158-1166, 2017 | 518 | 2017 |
| Structural impact on SARS-CoV-2 spike protein by D614G substitution J Zhang, Y Cai, T Xiao, J Lu, H Peng, SM Sterling, RM Walsh Jr, ... Science 372 (6541), 525-530, 2021 | 379 | 2021 |
| The primacy of affinity over clustering in regulation of adhesiveness of the integrin αLβ2 M Kim, CV Carman, W Yang, A Salas, TA Springer The Journal of cell biology 167 (6), 1241-1253, 2004 | 300 | 2004 |
| Membrane fusion and immune evasion by the spike protein of SARS-CoV-2 Delta variant J Zhang, T Xiao, Y Cai, CL Lavine, H Peng, H Zhu, K Anand, P Tong, ... Science 374 (6573), 1353-1360, 2021 | 278 | 2021 |
| Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants Y Cai, J Zhang, T Xiao, CL Lavine, S Rawson, H Peng, H Zhu, K Anand, ... Science 373 (6555), 642-648, 2021 | 227 | 2021 |
| New differentiation pathway for double-negative regulatory T cells that regulates the magnitude of immune responses D Zhang, W Yang, N Degauque, Y Tian, A Mikita, XX Zheng Blood 109 (9), 4071-4079, 2007 | 162 | 2007 |
| Small Molecule Integrin Antagonists that Bind to the β2 Subunit I-like Domain and Activate Signals in One Direction and Block Them in the Other M Shimaoka, A Salas, W Yang, G Weitz-Schmidt, TA Springer Immunity 19 (3), 391-402, 2003 | 156 | 2003 |
| Intersubunit signal transmission in integrins by a receptor-like interaction with a pull spring W Yang, M Shimaoka, A Salas, J Takagi, TA Springer Proceedings of the National Academy of Sciences 101 (9), 2906-2911, 2004 | 124 | 2004 |
| Structural and functional impact by SARS-CoV-2 Omicron spike mutations J Zhang, Y Cai, C Lavine, H Peng, H Zhu, K Anand, P Tong, A Gautam, ... bioRxiv, 2022 | 108 | 2022 |
| Activation of integrin β-subunit I-like domains by one-turn C-terminal α-helix deletions W Yang, M Shimaoka, JF Chen, TA Springer Proceedings of the National Academy of Sciences 101 (8), 2333-2338, 2004 | 79 | 2004 |
| Regulation of outside-in signaling and affinity by the β2 I domain of integrin αLβ2 JF Chen, W Yang, M Kim, CV Carman, TA Springer Proceedings of the National Academy of Sciences 103 (35), 13062-13067, 2006 | 64 | 2006 |
| AL-57, a ligand-mimetic antibody to integrin LFA-1, reveals chemokine-induced affinity up-regulation in lymphocytes M Shimaoka, M Kim, EH Cohen, W Yang, N Astrof, D Peer, A Salas, ... Proceedings of the National Academy of Sciences 103 (38), 13991-13996, 2006 | 63 | 2006 |
| A New Method for Protein Coexpression in Escherichia coli Using Two Incompatible Plasmids W Yang, L Zhang, Z Lu, W Tao, Z Zhai Protein expression and purification 22 (3), 472-478, 2001 | 62 | 2001 |
| A small molecule agonist of an integrin, αLβ2 W Yang, CV Carman, M Kim, A Salas, M Shimaoka, TA Springer Journal of Biological Chemistry 281 (49), 37904-37912, 2006 | 48 | 2006 |
| Structural basis of activation-dependent binding of ligand-mimetic antibody AL-57 to integrin LFA-1 H Zhang, J Liu, W Yang, T Springer, M Shimaoka, J Wang Proceedings of the National Academy of Sciences 106 (43), 18345-18350, 2009 | 31 | 2009 |
| Construction of a versatile expression library for all human single-pass transmembrane proteins for receptor pairings by high throughput screening W Yang, SB Padkjær, J Wang, Z Sun, B Shan, L Yang, H Chen, L Kang, ... Journal of biotechnology 260, 18-30, 2017 | 25 | 2017 |
| High level expression, purification and activation of human dipeptidyl peptidase I from mammalian cells W Yang, W Xia, J Mao, D Xu, J Chen, S Feng, J Wang, H Li, CF Theisen, ... Protein expression and purification 76 (1), 59-64, 2011 | 13 | 2011 |
| Identification of inhibitor of apoptosis specific DNase in Xenopus egg extract Z Lu, W Yang, Q Cao, W Tao, J Hu, Z Zhai Chinese Science Bulletin 46 (17), 1449-1453, 2001 | 3 | 2001 |
| Recombinant Human DFF45 Inhibits Apoptosis-specific Endonuclease in a Cell-free System of Xenopus Egg Extracts. W Yang, ZG Lu, L Zhang, ZH Zhai Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica …, 2001 | 3 | 2001 |
| Biochemical Characterization of α‐Aspartyl Dipeptidase Cloning and Expression of Its Gene H Zhang, J Zhang, X Wang, W Yang, J Lu Annals of the New York Academy of Sciences 864 (1), 621-625, 1998 | 3 | 1998 |
Timothy SpringerHarvard Medical School, Childrens Hospital Boston在 crystal.harvard.edu 的电子邮件经过验证
