Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation H Xu, C Faber, T Uchiki, JW Fairman, J Racca, C Dealwis Proceedings of the National Academy of Sciences 103 (11), 4022-4027, 2006 | 90 | 2006 |
Structures of eukaryotic ribonucleotide reductase I define gemcitabine diphosphate binding and subunit assembly H Xu, C Faber, T Uchiki, J Racca, C Dealwis Proceedings of the National Academy of Sciences 103 (11), 4028-4033, 2006 | 86 | 2006 |
Inherited human sex reversal due to impaired nucleocytoplasmic trafficking of SRY defines a male transcriptional threshold YS Chen, JD Racca, NB Phillips, MA Weiss Proceedings of the National Academy of Sciences 110 (38), E3567-E3576, 2013 | 33 | 2013 |
Structure-Function Relationships in Human Testis-determining Factor SRY: AN AROMATIC BUTTRESS UNDERLIES THE SPECIFIC DNA-BENDING SURFACE OF A HIGH MOBILITY GROUP (HMG) BOX*♦ JD Racca, YS Chen, JD Maloy, N Wickramasinghe, NB Phillips, MA Weiss Journal of Biological Chemistry 289 (47), 32410-32429, 2014 | 21 | 2014 |
Mammalian testis-determining factor SRY and the enigma of inherited human sex reversal: frustrated induced fit in a bent protein-DNA complex NB Phillips, J Racca, YS Chen, R Singh, A Jancso-Radek, JT Radek, ... Journal of Biological Chemistry 286 (42), 36787-36807, 2011 | 21 | 2011 |
Sml1p is a dimer in solution: characterization of denaturation and renaturation of recombinant Sml1p V Gupta, CB Peterson, LT Dice, T Uchiki, J Racca, J Guo, Y Xu, R Hettich, ... Biochemistry 43 (26), 8568-8578, 2004 | 21 | 2004 |
Microsatellite-encoded domain in rodent Sry functions as a genetic capacitor to enable the rapid evolution of biological novelty YS Chen, JD Racca, PW Sequeira, NB Phillips, MA Weiss Proceedings of the National Academy of Sciences 110 (33), E3061-E3070, 2013 | 18 | 2013 |
Human sex determination at the edge of ambiguity: inherited XY sex reversal due to enhanced ubiquitination and proteasomal degradation of a master transcription factor JD Racca, YS Chen, Y Yang, NB Phillips, MA Weiss Journal of Biological Chemistry 291 (42), 22173-22195, 2016 | 14 | 2016 |
Tenuous transcriptional threshold of human sex determination. II. SRY exploits water-mediated clamp at the edge of ambiguity JD Racca, D Chatterjee, YS Chen, RK Rai, Y Yang, MM Georgiadis, ... Frontiers in Endocrinology 13, 1029177, 2022 | 2 | 2022 |
Tenuous transcriptional threshold of human sex determination. i. sry and swyer syndrome at the edge of ambiguity YS Chen, JD Racca, MA Weiss Frontiers in Endocrinology 13, 945030, 2022 | 1 | 2022 |
Inherited human xy sex reversal and gonadal neoplasia due to enhanced formation of non-specific enhanceosomes by an architectural transcription factor YS Chen, JD Racca, A Belgorosky, MA Weiss Journal of the Endocrine Society 5 (Suppl 1), A506, 2021 | 1 | 2021 |
Tenuous Transcriptional Threshold of Human Sex Determination. I YS Chen, JD Racca, MA Weiss SRY and Swyer Syndrome at the Edge of Ambiguity. Front. Endocrinol. 13 …, 2022 | | 2022 |
Inherited Human Sex Reversal due to Loss of a Water-Mediated Hydrogen Bond at a Conserved Protein-DNA Interface YS Chen, J Racca, D Amir, E Haas, MA Weiss bioRxiv, 2021.05. 05.442830, 2021 | | 2021 |
SUN-712 Familial 46, XY Complete Female External Sex Development with a Non-Mosaic Inherited SRY Gene Variation E Vaiani, YS Chen, P Ramirez, MS Baquedano, M Malosetti, J Racca, ... Journal of the Endocrine Society 4 (Supplement_1), SUN-712, 2020 | | 2020 |
OR15-5 Human Sex Determination at the Edge of Ambiguity: Impaired SRY Phosphorylation Attenuates Expression of the Male Program YS Chen, J Racca, N Phillips, M Weiss Journal of the Endocrine Society 3 (Supplement_1), OR15-5, 2019 | | 2019 |
Human Sex Determination at the Edge of Ambiguity: Biophysical Studies of Clinical Mutations in a Master Transcription Factor MA Weiss, YS Chen, J Racca, NB Phillips Biophysical Journal 112 (3), 516a, 2017 | | 2017 |
“Protein Un‐Design”: Evolutionary Origins of Native DNA‐Binding Architectures in Unfolded Polypeptides MA Weiss, JD Racca, YS Chen, NB Phillips The FASEB Journal 29, 563.12, 2015 | | 2015 |
Kinetic Control of a Developmental Switch: Design of a “Kinetic Rheostat” in a Bent Protein‐DNA Complex with Application to Human Sex Reversal JD Racca, YS Chen, V Bhatnagar, NB Phillips, MA Weiss The FASEB Journal 29, 880.21, 2015 | | 2015 |
" Experiments of Nature": Structure-function Studies of an Architectural Transcription Factor: Application to Male Sex Determination JD Racca Case Western Reserve University, 2015 | | 2015 |