关注
Josué Carvalho
Josué Carvalho
R&D Scientist, ALS Life Sciences Portugal
在 alsglobal.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
G-quadruplex, friend or foe: the role of the G-quartet in anticancer strategies
J Carvalho, JL Mergny, GF Salgado, JA Queiroz, C Cruz
Trends in Molecular Medicine 26 (9), 848-861, 2020
2182020
Aptamer-based targeted delivery of a G-quadruplex ligand in cervical cancer cells
J Carvalho, A Paiva, MP Cabral Campello, A Paulo, JL Mergny, ...
Scientific reports 9 (1), 7945, 2019
972019
Circular dichroism of G-Quadruplex: A laboratory experiment for the study of topology and ligand binding
J Carvalho, JA Queiroz, C Cruz
Journal of Chemical Education 94 (10), 1547-1551, 2017
862017
Fluorescent light-up acridine orange derivatives bind and stabilize KRAS-22RT G-quadruplex
J Carvalho, E Pereira, J Marquevielle, MPC Campello, JL Mergny, ...
Biochimie 144, 144-152, 2018
482018
Multicharged phthalocyanines as selective ligands for G-quadruplex DNA structures
CIV Ramos, SP Almeida, LMO Lourenço, PMR Pereira, R Fernandes, ...
Molecules 24 (4), 733, 2019
452019
Aptamer-guided acridine derivatives for cervical cancer
J Carvalho, J Lopes-Nunes, AC Lopes, MPC Campello, A Paulo, ...
Organic & Biomolecular Chemistry 17 (11), 2992-3002, 2019
402019
AS1411 derivatives as carriers of G-quadruplex ligands for cervical cancer cells
J Figueiredo, J Lopes-Nunes, J Carvalho, F Antunes, M Ribeiro, ...
International Journal of Pharmaceutics 568, 118511, 2019
372019
Phthalocyanines for G-quadruplex aptamers binding
J Lopes-Nunes, J Carvalho, J Figueiredo, CIV Ramos, LMO Lourenco, ...
Bioorganic chemistry 100, 103920, 2020
352020
Study of the interaction between indole-based compounds and biologically relevant G-quadruplexes
J Carvalho, P Nottelet, JL Mergny, JA Queiroz, GF Salgado, C Cruz
Biochimie 135, 186-195, 2017
322017
Phenanthroline polyazamacrocycles as G-quadruplex DNA binders
J Carvalho, T Quintela, NM Gueddouda, A Bourdoncle, JL Mergny, ...
Organic & Biomolecular Chemistry 16 (15), 2776-2786, 2018
302018
Metal-based G-quadruplex binders for cancer theranostics
E Palma, J Carvalho, C Cruz, A Paulo
Pharmaceuticals 14 (7), 605, 2021
282021
Development of a bioreactor system for cytotoxic evaluation of pharmacological compounds in living cells using NMR spectroscopy
J Carvalho, S Alves, MMCA Castro, CFGC Geraldes, JA Queiroz, ...
Journal of pharmacological and toxicological methods 95, 70-78, 2019
242019
Targeting Nucleolin By RNA G-Quadruplex-Forming Motif
J Figueiredo, A Miranda, J Lopes-Nunes, J Carvalho, D Alexandre, ...
Biochemical Pharmacology, 114418, 2021
202021
Aptamer-based approaches to detect nucleolin in prostate cancer
A Miranda, T Santos, J Carvalho, D Alexandre, A Jardim, CRF Caneira, ...
Talanta 226, 122037, 2021
192021
Human papillomavirus G-rich regions as potential antiviral drug targets
J Carvalho, J Lopes-Nunes, M Campello, A Paulo, J Milici, C Meyers, ...
Nucleic Acid Therapeutics 31 (1), 68-81, 2020
182020
Ligand screening to pre-miRNA 149 G-quadruplex investigated by molecular dynamics
J Carvalho, T Santos, R Carrilho, F Sousa, GF Salgado, JA Queiroz, ...
Journal of Biomolecular Structure and Dynamics 38 (8), 2276-2286, 2020
152020
Nanoaggregate-forming lipid-conjugated AS1411 aptamer as a promising tumor-targeted delivery system of anticancer agents in vitro
J Carvalho, J Lopes-Nunes, B Vialet, T Rosado, E Gallardo, J Vale, ...
Nanomedicine: Nanotechnology, Biology and Medicine, 102429, 2021
132021
Stabilization of novel immunoglobulin switch regions G-quadruplexes by naphthalene and quinoline-based ligands
J Carvalho, J Ferreira, P Pereira, E Coutinho, A Guedin, P Nottelet, ...
Tetrahedron 72 (9), 1229-1237, 2016
122016
Radiolabeled gold nanoseeds decorated with substance P peptides: synthesis, characterization and in vitro evaluation in glioblastoma cellular models
F Silva, A D’Onofrio, C Mendes, C Pinto, A Marques, MPC Campello, ...
International Journal of Molecular Sciences 23 (2), 617, 2022
112022
Synthesis and biological evaluation of new functionalized nitroindazolylacetonitrile derivatives
M Eddahmi, NMM Moura, L Bouissane, MAF Faustino, JAS Cavaleiro, ...
ChemistrySelect 4 (48), 14335-14342, 2019
102019
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