Design, synthesis, analgesic, anti-inflammatory activity of novel pyrazolones possessing aminosulfonyl pharmacophore as inhibitors of COX-2/5-LOX enzymes: Histopathological and … MA Abdelgawad, MB Labib, WAM Ali, G Kamel, AA Azouz, ... Bioorganic chemistry 78, 103-114, 2018 | 78 | 2018 |
Azole-hydrazone derivatives: Design, synthesis, in vitro biological evaluation, dual EGFR/HER2 inhibitory activity, cell cycle analysis and molecular docking study as … MB Labib, JN Philoppes, PF Lamie, ER Ahmed Bioorganic chemistry 76, 67-80, 2018 | 67 | 2018 |
Pyrazole-hydrazone derivatives as anti-inflammatory agents: Design, synthesis, biological evaluation, COX-1, 2/5-LOX inhibition and docking study MA Abdelgawad, MB Labib, M Abdel-Latif Bioorganic Chemistry 74, 212-220, 2017 | 60 | 2017 |
Synthesis, cyclooxygenase inhibition, anti-inflammatory evaluation and ulcerogenic liability of novel triarylpyrazoline derivatives as selective COX-2 inhibitors KRA Abdellatif, MA Abdelgawad, MB Labib, TH Zidan Bioorganic & Medicinal Chemistry Letters 25 (24), 5787-5791, 2015 | 44 | 2015 |
Design, synthesis of novel isoindoline hybrids as COX-2 inhibitors: Anti-inflammatory, analgesic activities and docking study MB Labib, SMZ Sharkawi, M El-Daly Bioorganic Chemistry 80, 70-80, 2018 | 40 | 2018 |
Novel tetrazole-based selective COX-2 inhibitors: Design, synthesis, anti-inflammatory activity, evaluation of PGE2, TNF-α, IL-6 and histopathological study MB Labib, AM Fayez, ELN EL-Shaymaa, M Awadallah, PA Halim Bioorganic Chemistry 104, 104308, 2020 | 39 | 2020 |
New pyrazole derivatives possessing amino/methanesulphonyl pharmacophore with good gastric safety profile: Design, synthesis, cyclooxygenase inhibition, anti-inflammatory … KRA Abdellatif, EKA Abdelall, PF Lamie, MB Labib, ES El-Nahaas, ... Bioorganic chemistry 95, 103540, 2020 | 37 | 2020 |
Design, synthesis, and screening of ortho-amino thiophene carboxamide derivatives on hepatocellular carcinomaas VEGFR-2Inhibitors MK AbdElhameid, MB Labib, AT Negmeldin, M Al-Shorbagy, ... Journal of Enzyme Inhibition and Medicinal Chemistry 33 (1), 1472-1493, 2018 | 31 | 2018 |
Synthesis of novel halogenated triarylpyrazoles as selective COX-2 inhibitors: anti-inflammatory activity, histopatholgical profile and in-silico studies KRA Abdellatif, EKA Abdelall, MB Labib, WAA Fadaly, TH Zidan Bioorganic Chemistry 105, 104418, 2020 | 24 | 2020 |
Synthesis and biological evaluation of new diarylpyrazole and triarylimidazoline derivatives as selective cox‐2 inhibitors KRA Abdellatif, MA Abdelgawad, MB Labib, TH Zidan Archiv der Pharmazie 350 (8), 1600386, 2017 | 23 | 2017 |
Novel pyrazole-based COX-2 inhibitors as potential anticancer agents: Design, synthesis, cytotoxic effect against resistant cancer cells, cell cycle arrest, apoptosis induction … PA Halim, SMZ Sharkawi, MB Labib Bioorganic Chemistry 131, 106273, 2023 | 20 | 2023 |
Synthesis of some novel thieno [3, 2-d] pyrimidines as potential cytotoxic small molecules against breast cancer M Kandeel, MK Abdelhameid, K Eman, MB Labib Chemical and Pharmaceutical Bulletin 61 (6), 637-647, 2013 | 18 | 2013 |
Design, synthesis of celecoxib-tolmetin drug hybrids as selective and potent COX-2 inhibitors KRA Abdellatif, EKA Abdelall, MB Labib, WAA Fadaly, TH Zidan Bioorganic chemistry 90, 103029, 2019 | 15 | 2019 |
Characterization of novel heterocyclic compounds based on 4-aryl-4H-chromene scaffold as anticancer agents: Design, synthesis, antiprofilerative activity against resistant … EKA Abdelall, HAH Elshemy, MB Labib, FEA Mohamed Bioorganic Chemistry 120, 105591, 2022 | 12 | 2022 |
Design, synthesis and biological evaluation of novel thiophene and theinopyrimidine derivatives as anticancer agents MB Labib, PF Lamie Medicinal Chemistry Research 25, 2607-2618, 2016 | 9 | 2016 |
Copper (II)-Catalyzed C–N Coupling of Aryl Halides and N-Nucleophiles Promoted by Quebrachitol or Diethylene Glycol F Du, Q Zhou, Y Fu, Y Chen, Y Wu, G Chen Synlett 30 (19), 2161-2168, 2019 | 8 | 2019 |
Novel pyrazole-oxadiazole hybrids possessing methanesulphonyl pharmacophore with good gastric safety profile: Design, synthesis, cyclooxygenase inhibition, anti-inflammatory … KRA Abdellatif, EKA Abdelall, PF Lamie, MB Labib, MM Abdelhakeem, ... Journal of Molecular Structure 1266, 133529, 2022 | 3 | 2022 |
Synthesis of certain 8-quinolyloxy and/or carbocyclic nitrogenous compounds for microbiological testing KRA Abdellatif, MB Labib, OM El-Badry, SMA Roshdy, MM El-Enany Beni-Suef University Journal of Basic and Applied Sciences 5 (2), 147-155, 2016 | 1 | 2016 |
Design, synthesis of novel chromene‐based scaffolds targeting hepatocellular carcinoma: Cell cycle arrest, cytotoxic effect against resistant cancer cells, apoptosis induction … EKA Abdelall, HAH Elshemy, MB Labib, FEA Mohamed Drug Development Research 85 (1), e22133, 2024 | | 2024 |