Suppression of canonical Wnt/β-catenin signaling by nuclear plakoglobin recapitulates phenotype of arrhythmogenic right ventricular cardiomyopathy E Garcia-Gras, R Lombardi, MJ Giocondo, JT Willerson, MD Schneider, ... The Journal of clinical investigation 116 (7), 2012-2021, 2006 | 723 | 2006 |
The hippo pathway is activated and is a causal mechanism for adipogenesis in arrhythmogenic cardiomyopathy SN Chen, P Gurha, R Lombardi, A Ruggiero, JT Willerson, AJ Marian Circulation research 114 (3), 454-468, 2014 | 285 | 2014 |
Myocardial collagen turnover in hypertrophic cardiomyopathy R Lombardi, S Betocchi, MA Losi, CG Tocchetti, M Aversa, M Miranda, ... Circulation 108 (12), 1455-1460, 2003 | 260 | 2003 |
Myozenin 2 is a novel gene for human hypertrophic cardiomyopathy A Osio, L Tan, SN Chen, R Lombardi, SF Nagueh, S Shete, R Roberts, ... Circulation research 100 (6), 766-768, 2007 | 214 | 2007 |
Nuclear plakoglobin is essential for differentiation of cardiac progenitor cells to adipocytes in arrhythmogenic right ventricular cardiomyopathy R Lombardi, M da Graca Cabreira-Hansen, A Bell, RR Fromm, ... Circulation research 109 (12), 1342-1353, 2011 | 185 | 2011 |
Genetic fate mapping identifies second heart field progenitor cells as a source of adipocytes in arrhythmogenic right ventricular cardiomyopathy R Lombardi, J Dong, G Rodriguez, A Bell, TK Leung, RJ Schwartz, ... Circulation research 104 (9), 1076-1084, 2009 | 181 | 2009 |
Determinants of atrial fibrillation development in patients with hypertrophic cardiomyopathy MA Losi, S Betocchi, M Aversa, R Lombardi, M Miranda, G D'Alessandro, ... The American journal of cardiology 94 (7), 895-900, 2004 | 165 | 2004 |
Human Molecular Genetic and Functional Studies Identify TRIM63, Encoding Muscle RING Finger Protein 1, as a Novel Gene for Human Hypertrophic … SN Chen, G Czernuszewicz, Y Tan, R Lombardi, J Jin, JT Willerson, ... Circulation research 111 (7), 907-919, 2012 | 153 | 2012 |
Resolution of established cardiac hypertrophy and fibrosis and prevention of systolic dysfunction in a transgenic rabbit model of human cardiomyopathy through thiol-sensitive … R Lombardi, G Rodriguez, SN Chen, CM Ripplinger, W Li, J Chen, ... Circulation 119 (10), 1398-1407, 2009 | 141 | 2009 |
Antifibrotic effects of antioxidant N-acetylcysteine in a mouse model of human hypertrophic cardiomyopathy mutation AJ Marian, V Senthil, SN Chen, R Lombardi Journal of the American College of Cardiology 47 (4), 827-834, 2006 | 134 | 2006 |
DNA Damage Response/TP53 Pathway Is Activated and Contributes to the Pathogenesis of Dilated Cardiomyopathy Associated with Lamin A/C Mutations SN Chen, R Lombardi, J Karmouch, JY Tsai, GZ Czernuszewicz, M Taylor, ... Circulation Research, 2019 | 115 | 2019 |
Exercise capacity in hypertrophic cardiomyopathy depends on left ventricular diastolic function C Briguori, S Betocchi, M Romano, F Manganelli, MA Losi, Q Ciampi, ... The American journal of cardiology 84 (3), 309-315, 1999 | 114 | 1999 |
Metabolomic distinction and insights into the pathogenesis of human primary dilated cardiomyopathy D Alexander, R Lombardi, G Rodriguez, MM Mitchell, AJ Marian European journal of clinical investigation 41 (5), 527-538, 2011 | 101 | 2011 |
Hemodynamic determinants of exercise-induced abnormal blood pressure response in hypertrophic cardiomyopathy Q Ciampi, S Betocchi, R Lombardi, F Manganelli, G Storto, MA Losi, ... Journal of the American College of Cardiology 40 (2), 278-284, 2002 | 99 | 2002 |
Cardiac Fibro-Adipocyte Progenitors Express Desmosome Proteins and Preferentially Differentiate to Adipocytes Upon Deletion of the Desmoplakin Gene R Lombardi, SN Chen, A Ruggiero, P Gurha, GZ Czernuszewicz, ... Circulation Research 119 (1), 41-54., 2016 | 96 | 2016 |
Genome-wide mapping of modifier chromosomal loci for human hypertrophic cardiomyopathy EW Daw, SN Chen, G Czernuszewicz, R Lombardi, Y Lu, J Ma, R Roberts, ... Human molecular genetics 16 (20), 2463-2471, 2007 | 89 | 2007 |
Molecular genetics and pathogenesis of arrhythmogenic right ventricular cardiomyopathy: a disease of cardiac stem cells R Lombardi, AJ Marian Pediatric cardiology 32, 360-365, 2011 | 75 | 2011 |
Differential interactions of thin filament proteins in two cardiac troponin T mouse models of hypertrophic and dilated cardiomyopathies R Lombardi, A Bell, V Senthil, J Sidhu, M Noseda, R Roberts, AJ Marian Cardiovascular research 79 (1), 109-117, 2008 | 69 | 2008 |
Enhanced transmural fiber rotation and connexin 43 heterogeneity are associated with an increased upper limit of vulnerability in a transgenic rabbit model of human … CM Ripplinger, W Li, J Hadley, J Chen, F Rothenberg, R Lombardi, ... Circulation research 101 (10), 1049-1057, 2007 | 66 | 2007 |
Suppression of activated FOXO transcription factors in the heart prolongs survival in a mouse model of laminopathies G Auguste, P Gurha, R Lombardi, C Coarfa, JT Willerson, AJ Marian Circulation Research 122 (5), 678-692, 2018 | 64 | 2018 |