Biological insights from 108 schizophrenia-associated genetic loci C Pantelis, GN Papadimitriou, S Papiol, E Parkhomenko, MT Pato, ... Nature 511 (7510), 421-427, 2014 | 7437 | 2014 |
Analysis of shared heritability in common disorders of the brain Brainstorm Consortium, V Anttila, B Bulik-Sullivan, HK Finucane, ... Science 360 (6395), eaap8757, 2018 | 1372 | 2018 |
Modeling linkage disequilibrium increases accuracy of polygenic risk scores BJ Vilhjálmsson, J Yang, HK Finucane, A Gusev, S Lindström, S Ripke, ... The american journal of human genetics 97 (4), 576-592, 2015 | 1351 | 2015 |
Mapping genomic loci implicates genes and synaptic biology in schizophrenia V Trubetskoy, AF Pardiñas, T Qi, G Panagiotaropoulou, S Awasthi, ... Nature 604 (7906), 502-508, 2022 | 1281 | 2022 |
Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases A Gusev, SH Lee, G Trynka, H Finucane, BJ Vilhjálmsson, H Xu, C Zang, ... The American Journal of Human Genetics 95 (5), 535-552, 2014 | 656 | 2014 |
Genomic dissection of bipolar disorder and schizophrenia, including 28 subphenotypes DM Ruderfer, S Ripke, A McQuillin, J Boocock, EA Stahl, JMW Pavlides, ... Cell 173 (7), 1705-1715. e16, 2018 | 528 | 2018 |
Evaluating the heritability explained by known susceptibility variants: a survey of ten complex diseases HC So, AHS Gui, SS Cherny, PC Sham Genetic epidemiology 35 (5), 310-317, 2011 | 317 | 2011 |
Exploring diseases/traits and blood proteins causally related to expression of ACE2, the putative receptor of SARS-CoV-2: A Mendelian Randomization analysis highlights … S Rao, A Lau, HC So Diabetes Care, 2020 | 300 | 2020 |
Low copy number of the salivary amylase gene predisposes to obesity M Falchi, JS El-Sayed Moustafa, P Takousis, F Pesce, A Bonnefond, ... Nature genetics 46 (5), 492-497, 2014 | 282 | 2014 |
Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept B Franke, JL Stein, S Ripke, V Anttila, DP Hibar, KJE Van Hulzen, ... Nature neuroscience 19 (3), 420-431, 2016 | 237 | 2016 |
Complement genes contribute sex-biased vulnerability in diverse disorders N Kamitaki, A Sekar, RE Handsaker, H De Rivera, K Tooley, DL Morris, ... Nature 582 (7813), 577-581, 2020 | 184 | 2020 |
Estimation of genetic correlation via linkage disequilibrium score regression and genomic restricted maximum likelihood G Ni, G Moser, S Ripke, BM Neale, A Corvin, JTR Walters, KH Farh, ... The American Journal of Human Genetics 102 (6), 1185-1194, 2018 | 151 | 2018 |
Causal associations of short and long sleep durations with 12 cardiovascular diseases: linear and nonlinear Mendelian randomization analyses in UK Biobank S Ai, J Zhang, G Zhao, N Wang, G Li, HC So, Y Liu, SWH Chau, J Chen, ... European Heart Journal 42 (34), 3349-3357, 2021 | 147 | 2021 |
Analysis of genome-wide association data highlights candidates for drug repositioning in psychiatry HC So, CKL Chau, WT Chiu, KS Ho, CP Lo, SHY Yim, PC Sham Nature neuroscience 20 (10), 1342-1349, 2017 | 144 | 2017 |
A comparison of ten polygenic score methods for psychiatric disorders applied across multiple cohorts G Ni, J Zeng, JA Revez, Y Wang, Z Zheng, T Ge, R Restuadi, J Kiewa, ... Biological psychiatry 90 (9), 611-620, 2021 | 142 | 2021 |
Genetic correlation between amyotrophic lateral sclerosis and schizophrenia RL McLaughlin, D Schijven, W Van Rheenen, KR Van Eijk, M O’Brien, ... Nature communications 8 (1), 14774, 2017 | 138 | 2017 |
Drug repositioning for schizophrenia and depression/anxiety disorders: A machine learning approach leveraging expression data K Zhao, HC So IEEE journal of biomedical and health informatics 23 (3), 1304-1315, 2018 | 99* | 2018 |
Uncovering the total heritability explained by all true susceptibility variants in a genome‐wide association study HC So, M Li, PC Sham Genetic epidemiology 35 (6), 447-456, 2011 | 90 | 2011 |
Risk prediction of complex diseases from family history and known susceptibility loci, with applications for cancer screening HC So, JSH Kwan, SS Cherny, PC Sham The American Journal of Human Genetics 88 (5), 548-565, 2011 | 89 | 2011 |
Sex-dependent shared and nonshared genetic architecture across mood and psychotic disorders GAM Blokland, J Grove, CY Chen, C Cotsapas, S Tobet, R Handa, ... Biological psychiatry 91 (1), 102-117, 2022 | 84 | 2022 |