| Signatures of Adaptation to Obligate Biotrophy in the Hyaloperonospora arabidopsidis Genome L Baxter, S Tripathy, N Ishaque, N Boot, A Cabral, E Kemen, M Thines, ... science 330 (6010), 1549-1551, 2010 | 520 | 2010 |
| Signal transduction controls heterogeneous NF-κB dynamics and target gene expression through cytokine-specific refractory states A Adamson, C Boddington, P Downton, W Rowe, J Bagnall, C Lam, ... Nature communications 7 (1), 12057, 2016 | 82 | 2016 |
| Circadian rhythms in adaptive immunity P Downton, JO Early, JE Gibbs Immunology 161 (4), 268-277, 2020 | 69 | 2020 |
| Temperature regulates NF-κB dynamics and function through timing of A20 transcription CV Harper, DJ Woodcock, C Lam, M Garcia-Albornoz, A Adamson, ... Proceedings of the National Academy of Sciences 115 (22), E5243-E5249, 2018 | 67 | 2018 |
| Quantitative analysis of competitive cytokine signaling predicts tissue thresholds for the propagation of macrophage activation J Bagnall, C Boddington, H England, R Brignall, P Downton, Z Alsoufi, ... Science signaling 11 (540), eaaf3998, 2018 | 57 | 2018 |
| Nuclear receptor REVERBα is a state-dependent regulator of liver energy metabolism AL Hunter, CE Pelekanou, A Adamson, P Downton, NJ Barron, ... Proceedings of the National Academy of Sciences 117 (41), 25869-25879, 2020 | 48 | 2020 |
| Adipocyte NR1D1 dictates adipose tissue expansion during obesity AL Hunter, CE Pelekanou, NJ Barron, RC Northeast, M Grudzien, ... Elife 10, e63324, 2021 | 38 | 2021 |
| Chronic inflammatory arthritis drives systemic changes in circadian energy metabolism P Downton, F Sanna, R Maidstone, TM Poolman, EA Hayter, SH Dickson, ... Proceedings of the National Academy of Sciences 119 (18), e2112781119, 2022 | 16 | 2022 |
| The histone methyltransferase Ezh2 restrains macrophage inflammatory responses GB Kitchen, T Hopwood, TG Ramamoorthy, P Downton, N Begley, ... The FASEB Journal 35 (10), 2021 | 15 | 2021 |
| Asymmetry between activation and deactivation during a transcriptional pulse LSS Dunham, H Momiji, CV Harper, PJ Downton, K Hey, A McNamara, ... Cell Systems 5 (6), 646-653. e5, 2017 | 12 | 2017 |
| Consequences of collagen induced inflammatory arthritis on circadian regulation of the gut microbiome DA Simpkins, P Downton, KJ Gray, SH Dickson, RJ Maidstone, JE Konkel, ... The FASEB Journal 37 (1), 2023 | 8 | 2023 |
| Identification of diurnal rhythmic blood markers in bronchial asthma K Krakowiak, RJ Maidstone, A Chakraborty, AC Kendall, A Nicolaou, ... ERJ Open Research 9 (4), 2023 | 4 | 2023 |
| L1 Blood immune cells clock mechanism is altered in asthma, with a time-of-day dependent response to steroids in vitro K Krakowiak, P Downton, J Blaikley, H Durrington Thorax 76 (Suppl 1), A230-A230, 2021 | 3 | 2021 |
| Overexpression of IκB⍺ modulates NF-κB activation of inflammatory target gene expression P Downton, JS Bagnall, H England, DG Spiller, NE Humphreys, ... Frontiers in Molecular Biosciences 10, 1187187, 2023 | 2 | 2023 |
| Spiller David G., Jackson Dean A., Müller Werner, Muldoon Mark, White Michael RH, Paszek Pawel. Quantitative analysis of competitive cytokine signaling predicts tissue … B James, B Christopher, E Hazel, B Ruth, D Polly, A Zainab, B James, ... Science Signaling 11, 540, 2018 | 2 | 2018 |
| Expression Of Clock Gene PER3 Is Altered In Asthma K Krakowiak, R Maidstone, J Blaikley, P Downton, H Durrington A32. UPDATES IN THE MOLECULAR AND CELLULAR UNDERPINNINGS OF ASTHMA, A1259-A1259, 2022 | 1 | 2022 |
| Fibroblast-like synoviocytes orchestrate daily rhythmic inflammation in arthritis P Downton, SH Dickson, DW Ray, DA Bechtold, JE Gibbs Open Biology 14 (7), 240089, 2024 | | 2024 |
| Adipocyte REVERBα dictates adipose tissue expansion during obesity A Louise Hunter, CE Pelekanou, NJ Barron, RC Northeast, A Adamson, ... bioRxiv, 2020.09. 23.308155, 2020 | | 2020 |
| Adipocyte REVERBα dictates adipose tissue expansion during obesity AL Hunter, CE Pelekanou, NJ Barron, RC Northeast, ASI Hodson, ... | | 2020 |
| Ezh2 restrains macrophage inflammatory responses, and is critical for neutrophil migration in response to pulmonary infection GB Kitchen, T Hopwood, TG Ramamoorthy, P Downton, N Begley, ... bioRxiv, 2020.07. 24.219154, 2020 | | 2020 |
