Fragment merging approach for the design of thiazole/thiazolidine clubbed pyrazoline derivatives as anti-inflammatory agents: Synthesis, biopharmacological evaluation and … MK Elgohary, SR Abd El Hadi, MF Abo-Ashour, ME Abo-El Fetoh, H Afify, ... Bioorganic Chemistry 139, 106724, 2023 | 7 | 2023 |
Fenamates and ibuprofen as foundational components in the synthesis of innovative, targeted COX-2 anti-inflammatory drugs, undergoing thorough biopharmacological assessments … MK Elgohary, MS Elkotamy, MA Alkabbani, HA Abdel-Aziz Bioorganic Chemistry 147, 107393, 2024 | 3 | 2024 |
Design, Synthesis and Biological Assessment of N′-(2-Oxoindolin-3-ylidene)-6-methylimidazo[2,1-b]thiazole-5-carbohydrazides as Potential Anti-Proliferative … NA Alshaye, MK Elgohary, MS Elkotamy, HA Abdel-Aziz Pharmaceuticals 17 (2), 216, 2024 | 2 | 2024 |
Design, Synthesis, and Biological Evaluation of Novel Phenoxy Acetic Acid Derivatives as Selective COX-2 Inhibitors Coupled with Comprehensive Bio-Pharmacological Inquiry … NA Alshaye, MK Elgohary, MS Elkotamy, HA Abdel-Aziz Molecules 29 (6), 1309, 2024 | 2 | 2024 |
Novel imidazo [2, 1-b] thiazoles and imidazo [1, 2-a] pyridines tethered with indolinone motif as VEGFR-2 inhibitors and apoptotic inducers: Design, synthesis and biological … MS Elkotamy, MK Elgohary, ST Al-Rashood, H Almahli, WM Eldehna, ... Bioorganic Chemistry 151, 107644, 2024 | 1 | 2024 |
Development of new LSM-83177 analogues as anti-tumor agents against colorectal cancer targeting p53-MDM2 interaction MK Elgohary, MS Elkotamy, T Al-Warhi, WM Eldehna, HA Abdel-Aziz Bioorganic Chemistry, 107766, 2024 | | 2024 |
Novel anti-inflammatory agents featuring phenoxy acetic acid moiety as a pharmacophore for selective COX-2 inhibitors: Synthesis, biological evaluation, histopathological … MK Elgohary, MF Abo-Ashour, SR Abd El Hadi, MA El Hassab, ... Bioorganic Chemistry, 107727, 2024 | | 2024 |
Discovering new CDK2 inhibitors by molecular docking and drug-likeness-based virtual screening for potential anticancer uses. MS Elkotamy, MK Elgohary, IA Elkelesh, AM Hamdy ERU Research Journal, 2024 | | 2024 |