Rac function is crucial for cell migration but is not required for spreading and focal adhesion formation A Steffen, M Ladwein, GA Dimchev, A Hein, L Schwenkmezger, S Arens, ... Journal of cell science 126 (20), 4572-4588, 2013 | 189 | 2013 |
Temporally specified genetic ablation of neurogenesis impairs cognitive recovery after traumatic brain injury CA Blaiss, TS Yu, G Zhang, J Chen, G Dimchev, LF Parada, CM Powell, ... Journal of Neuroscience 31 (13), 4906-4916, 2011 | 170 | 2011 |
FMNL formins boost lamellipodial force generation F Kage, M Winterhoff, V Dimchev, J Mueller, T Thalheim, A Freise, ... Nature communications 8 (1), 14832, 2017 | 138 | 2017 |
Loss of Ena/VASP interferes with lamellipodium architecture, motility and integrin-dependent adhesion J Damiano-Guercio, L Kurzawa, J Mueller, G Dimchev, M Schaks, ... Elife 9, e55351, 2020 | 84 | 2020 |
Cryo-electron tomography structure of Arp2/3 complex in cells reveals new insights into the branch junction F Fäßler, G Dimchev, VV Hodirnau, W Wan, FKM Schur Nature communications 11 (1), 6437, 2020 | 59 | 2020 |
Efficiency of lamellipodia protrusion is determined by the extent of cytosolic actin assembly G Dimchev, A Steffen, F Kage, V Dimchev, J Pernier, MF Carlier, K Rottner Molecular Biology of the Cell 28 (10), 1311-1325, 2017 | 47 | 2017 |
Lamellipodin tunes cell migration by stabilizing protrusions and promoting adhesion formation G Dimchev, B Amiri, AC Humphries, M Schaks, V Dimchev, TEB Stradal, ... Journal of cell science 133 (7), jcs239020, 2020 | 36 | 2020 |
Phospho-tyrosine phosphatase inhibitor Bpv (Hopic) enhances C2C12 myoblast migration in vitro. Requirement of PI3K/AKT and MAPK/ERK pathways GA Dimchev, N Al-Shanti, CE Stewart Journal of muscle research and cell motility 34, 125-136, 2013 | 32 | 2013 |
Induced Arp2/3 complex depletion increases FMNL2/3 formin expression and filopodia formation V Dimchev, I Lahmann, SA Koestler, F Kage, G Dimchev, A Steffen, ... Frontiers in cell and developmental biology 9, 634708, 2021 | 31 | 2021 |
Computational toolbox for ultrastructural quantitative analysis of filament networks in cryo-ET data G Dimchev, B Amiri, F Fäßler, M Falcke, FKM Schur Journal of Structural Biology 213 (4), 107808, 2021 | 27 | 2021 |
Cul3 regulates cytoskeleton protein homeostasis and cell migration during a critical window of brain development J Morandell, LA Schwarz, B Basilico, S Tasciyan, G Dimchev, A Nicolas, ... Nature communications 12 (1), 3058, 2021 | 25 | 2021 |
Activated lymphocytes secretome inhibits differentiation and induces proliferation of C2C12 myoblasts N Al-Shanti, P Durcan, S Al-Dabbagh, GA Dimchev, CE Stewart Cellular Physiology and Biochemistry 33 (1), 117-128, 2014 | 17 | 2014 |
ArpC5 isoforms regulate Arp2/3 complex–dependent protrusion through differential Ena/VASP positioning F Fäßler, MG Javoor, J Datler, H Döring, FW Hofer, G Dimchev, ... Science Advances 9 (3), eadd6495, 2023 | 15 | 2023 |
Micromanipulation techniques allowing analysis of morphogenetic dynamics and turnover of cytoskeletal regulators G Dimchev, K Rottner JoVE (Journal of Visualized Experiments), e57643, 2018 | 5 | 2018 |
Cryo-electron tomography workflows for quantitative analysis of actin networks involved in cell migration F Fäßler, G Dimchev, VV Hodirnau, B Zens, C Möhl, F Bradke, F Schur Microscopy and Microanalysis 26 (S2), 2518-2519, 2020 | 4 | 2020 |
Novel cryo-electron tomography structure of Arp2/3 complex in cells reveals mechanisms of branch formation F Fäßler, G Dimchev, VV Hodirnau, W Wan, FKM Schur bioRxiv, 2020.08. 25.266262, 2020 | 3 | 2020 |
Cellular regulators of myoblast migration and myogenesis GA Dimchev Manchester Metropolitan University, 2012 | 2 | 2012 |
A matlab toolbox for ultrastructural analysis of filament networks in cryo-ET data B Amiri, G Dimchev, F Fäßler, M Falcke, FK Schur Biophysical Journal 121 (3), 11a, 2022 | | 2022 |
First person–Georgi Dimchev G Dimchev Journal of Cell Science 133 (7), 2020 | | 2020 |
Tyrosine kinases are enzymes responsible for the activation of many proteins by signal transduction cascades. Menu GA Dimchev, N Al-Shanti, CE Stewart | | |