The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy M Lazarou, DA Sliter, LA Kane, SA Sarraf, C Wang, JL Burman, ... Nature 524 (7565), 309-314, 2015 | 2406 | 2015 |
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL SM Jin, M Lazarou, C Wang, LA Kane, DP Narendra, RJ Youle Journal of Cell Biology 191 (5), 933-942, 2010 | 1387 | 2010 |
PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity LA Kane, M Lazarou, AI Fogel, Y Li, K Yamano, SA Sarraf, S Banerjee, ... Journal of Cell Biology 205 (2), 143-153, 2014 | 1264 | 2014 |
BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis K McArthur, LW Whitehead, JM Heddleston, L Li, BS Padman, V Oorschot, ... Science 359 (6378), eaao6047, 2018 | 718 | 2018 |
Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase Parkin M Lazarou, SM Jin, LA Kane, RJ Youle Developmental cell 22 (2), 320-333, 2012 | 688 | 2012 |
Atg8 family LC3/GABARAP proteins are crucial for autophagosome–lysosome fusion but not autophagosome formation during PINK1/Parkin mitophagy and starvation TN Nguyen, BS Padman, J Usher, V Oorschot, G Ramm, M Lazarou Journal of Cell Biology 215 (6), 857-874, 2016 | 601 | 2016 |
Deciphering the molecular signals of PINK1/Parkin mitophagy TN Nguyen, BS Padman, M Lazarou Trends in cell biology 26 (10), 733-744, 2016 | 571 | 2016 |
Mitochondrial respiratory chain supercomplexes are destabilized in Barth Syndrome patients RMT McKenzie M, Lazarou M, Thorburn DR J. Mol. Biol 361, 462-469, 2006 | 482 | 2006 |
Analysis of the assembly profiles for mitochondrial-and nuclear-DNA-encoded subunits into complex I M Lazarou, M McKenzie, A Ohtake, DR Thorburn, MT Ryan Molecular and cellular biology, 2007 | 289 | 2007 |
Bacteriophage transcytosis provides a mechanism to cross epithelial cell layers S Nguyen, K Baker, BS Padman, R Patwa, RA Dunstan, TA Weston, ... MBio 8 (6), 10.1128/mbio. 01874-17, 2017 | 287 | 2017 |
Crystal structure of the mitochondrial chaperone TIM9• 10 reveals a six-bladed α-propeller CT Webb, MA Gorman, M Lazarou, MT Ryan, JM Gulbis Molecular cell 21 (1), 123-133, 2006 | 270 | 2006 |
Parkin and mitophagy in cancer JP Bernardini, M Lazarou, G Dewson Oncogene 36 (10), 1315-1327, 2017 | 256 | 2017 |
Assembly of mitochondrial complex I and defects in disease M Lazarou, DR Thorburn, MT Ryan, M McKenzie Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1793 (1), 78-88, 2009 | 250 | 2009 |
PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding M Lazarou, DP Narendra, SM Jin, E Tekle, S Banerjee, RJ Youle The Journal of Cell Biology, 2013 | 247 | 2013 |
Human CIA30 is involved in the early assembly of mitochondrial complex I and mutations in its gene cause disease CJR Dunning, M McKenzie, C Sugiana, M Lazarou, J Silke, A Connelly, ... The EMBO journal 26 (13), 3227-3237, 2007 | 235 | 2007 |
Structure, function, and regulation of mitofusin‐2 in health and disease G Chandhok, M Lazarou, B Neumann Biological Reviews 93 (2), 933-949, 2018 | 213 | 2018 |
LC3/GABARAPs drive ubiquitin-independent recruitment of Optineurin and NDP52 to amplify mitophagy BS Padman, TN Nguyen, L Uoselis, M Skulsuppaisarn, LK Nguyen, ... Nature communications 10 (1), 408, 2019 | 197 | 2019 |
Assembly of nuclear DNA‐encoded subunits into mitochondrial complex IV, and their preferential integration into supercomplex forms in patient mitochondria M Lazarou, SM Smith, DR Thorburn, MT Ryan, M McKenzie The FEBS journal 276 (22), 6701-6713, 2009 | 114 | 2009 |
Analysis of mitochondrial subunit assembly into respiratory chain complexes using Blue Native polyacrylamide gel electrophoresis M McKenzie, M Lazarou, DR Thorburn, MT Ryan Analytical biochemistry 364 (2), 128-137, 2007 | 113 | 2007 |
Inhibition of Bak activation by VDAC2 is dependent on the Bak transmembrane anchor M Lazarou, D Stojanovski, AE Frazier, A Kotevski, G Dewson, WJ Craigen, ... Journal of Biological Chemistry 285 (47), 36876-36883, 2010 | 109 | 2010 |