Olaparib in patients with metastatic castration-resistant prostate cancer with DNA repair gene aberrations (TOPARP-B): a multicentre, open-label, randomised, phase 2 trial J Mateo, N Porta, D Bianchini, U McGovern, T Elliott, R Jones, I Syndikus, ... The Lancet Oncology 21 (1), 162-174, 2020 | 574 | 2020 |
Circulating cell-free DNA to guide prostate cancer treatment with PARP inhibition J Goodall, J Mateo, W Yuan, H Mossop, N Porta, S Miranda, ... Cancer discovery 7 (9), 1006-1017, 2017 | 395 | 2017 |
IL-23 secreted by myeloid cells drives castration-resistant prostate cancer A Calcinotto, C Spataro, E Zagato, D Di Mitri, V Gil, M Crespo, ... Nature 559 (7714), 363-369, 2018 | 332 | 2018 |
Visceral disease in castration-resistant prostate cancer CJ Pezaro, A Omlin, D Lorente, DN Rodrigues, R Ferraldeschi, ... European urology 65 (2), 270-273, 2014 | 237 | 2014 |
Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer DN Rodrigues, P Rescigno, D Liu, W Yuan, S Carreira, MB Lambros, ... The Journal of clinical investigation 128 (10), 4441-4453, 2018 | 212 | 2018 |
Decline in circulating tumor cell count and treatment outcome in advanced prostate cancer D Lorente, D Olmos, J Mateo, D Bianchini, G Seed, M Fleisher, DC Danila, ... European urology 70 (6), 985-992, 2016 | 160 | 2016 |
Targeting the p300/CBP axis in lethal prostate cancer J Welti, A Sharp, N Brooks, W Yuan, C McNair, SN Chand, A Pal, ... Cancer Discovery 11 (5), 1118-1137, 2021 | 150 | 2021 |
SPOP-mutated/CHD1-deleted lethal prostate cancer and abiraterone sensitivity G Boysen, DN Rodrigues, P Rescigno, G Seed, D Dolling, R Riisnaes, ... Clinical cancer research 24 (22), 5585-5593, 2018 | 143 | 2018 |
BRD4 promotes DNA repair and mediates the formation of TMPRSS2-ERG gene rearrangements in prostate cancer X Li, GH Baek, SG Ramanand, A Sharp, Y Gao, W Yuan, J Welti, ... Cell reports 22 (3), 796-808, 2018 | 140 | 2018 |
Targeting bromodomain and extra-terminal (BET) family proteins in castration-resistant prostate cancer (CRPC) J Welti, A Sharp, W Yuan, D Dolling, D Nava Rodrigues, I Figueiredo, ... Clinical Cancer Research 24 (13), 3149-3162, 2018 | 133 | 2018 |
CHD1 loss sensitizes prostate cancer to DNA damaging therapy by promoting error-prone double-strand break repair TR Shenoy, G Boysen, MY Wang, QZ Xu, W Guo, FM Koh, C Wang, ... Annals of Oncology 28 (7), 1495-1507, 2017 | 118 | 2017 |
Single-cell analyses of prostate cancer liquid biopsies acquired by apheresis MB Lambros, G Seed, S Sumanasuriya, V Gil, M Crespo, M Fontes, ... Clinical Cancer Research 24 (22), 5635-5644, 2018 | 110 | 2018 |
The association of PI3 kinase signaling and chemoresistance in advanced ovarian cancer CP Carden, A Stewart, P Thavasu, E Kipps, L Pope, M Crespo, S Miranda, ... Molecular cancer therapeutics 11 (7), 1609-1617, 2012 | 107 | 2012 |
Differential impact of RB status on E2F1 reprogramming in human cancer C McNair, K Xu, AC Mandigo, M Benelli, B Leiby, D Rodrigues, J Lindberg, ... The Journal of clinical investigation 128 (1), 341-358, 2018 | 102 | 2018 |
Biomarkers associating with PARP inhibitor benefit in prostate cancer in the TOPARP-B trial S Carreira, N Porta, S Arce-Gallego, G Seed, A Llop-Guevara, D Bianchini, ... Cancer discovery 11 (11), 2812-2827, 2021 | 100 | 2021 |
Second-generation HSP90 inhibitor onalespib blocks mRNA splicing of androgen receptor variant 7 in prostate cancer cells R Ferraldeschi, J Welti, MV Powers, W Yuan, T Smyth, G Seed, ... Cancer research 76 (9), 2731-2742, 2016 | 95 | 2016 |
First-in-human Phase I study of EZN-4176, a locked nucleic acid antisense oligonucleotide to exon 4 of the androgen receptor mRNA in patients with castration-resistant prostate … D Bianchini, A Omlin, C Pezaro, D Lorente, R Ferraldeschi, D Mukherji, ... British journal of cancer 109 (10), 2579-2586, 2013 | 90 | 2013 |
Toward a real liquid biopsy in metastatic breast and prostate cancer: Diagnostic LeukApheresis increases CTC yields in a European prospective multicenter study (CTCTrap) KC Andree, A Mentink, LL Zeune, LWMM Terstappen, NH Stoecklein, ... International journal of cancer 143 (10), 2584-2591, 2018 | 89 | 2018 |
EpCAMhigh and EpCAMlow circulating tumor cells in metastatic prostate and breast cancer patients S de Wit, M Manicone, E Rossi, R Lampignano, L Yang, B Zill, ... Oncotarget 9 (86), 35705, 2018 | 83 | 2018 |
Chromosomal analysis of Barrett's cells: demonstration of instability and detection of the metaplastic lineage involved P Chaves, M Crespo, C Ribeiro, C Laranjeira, AD Pereira, A Suspiro, ... Modern pathology 20 (7), 788-796, 2007 | 82 | 2007 |