Molecular mechanisms of diabetic cardiomyopathy H Bugger, ED Abel Diabetologia 57, 660-671, 2014 | 1016 | 2014 |
Mitochondrial energetics in the heart in obesity-related diabetes: direct evidence for increased uncoupled respiration and activation of uncoupling proteins S Boudina, S Sena, H Theobald, X Sheng, JJ Wright, XX Hu, S Aziz, ... Diabetes 56 (10), 2457-2466, 2007 | 694 | 2007 |
Disruption of the circadian clock within the cardiomyocyte influences myocardial contractile function, metabolism, and gene expression MS Bray, CA Shaw, MWS Moore, RAP Garcia, MM Zanquetta, DJ Durgan, ... American Journal of Physiology-Heart and Circulatory Physiology 294 (2 …, 2008 | 397 | 2008 |
Rodent models of diabetic cardiomyopathy H Bugger, ED Abel Disease models & mechanisms 2 (9-10), 454-466, 2009 | 348 | 2009 |
Contribution of impaired myocardial insulin signaling to mitochondrial dysfunction and oxidative stress in the heart S Boudina, H Bugger, S Sena, BT O'Neill, VG Zaha, O Ilkun, JJ Wright, ... Circulation 119 (9), 1272-1283, 2009 | 330 | 2009 |
Mitochondria in the diabetic heart H Bugger, ED Abel Cardiovascular research 88 (2), 229-240, 2010 | 327 | 2010 |
Mitochondrial ROS in myocardial ischemia reperfusion and remodeling H Bugger, K Pfeil Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1866 (7), 165768, 2020 | 280 | 2020 |
Mitochondrial reactive oxygen species in lipotoxic hearts induce post-translational modifications of AKAP121, DRP1, and OPA1 that promote mitochondrial fission K Tsushima, H Bugger, AR Wende, J Soto, GA Jenson, AR Tor, ... Circulation research 122 (1), 58-73, 2018 | 263 | 2018 |
Diabetic cardiomyopathy: does the type of diabetes matter? ME Hölscher, C Bode, H Bugger International journal of molecular sciences 17 (12), 2136, 2016 | 257 | 2016 |
Molecular mechanisms for myocardial mitochondrial dysfunction in the metabolic syndrome H Bugger, E Dale Abel Clinical science 114 (3), 195-210, 2008 | 251 | 2008 |
Heart failure and diabetes: metabolic alterations and therapeutic interventions: a state-of-the-art review from the Translational Research Committee of the Heart Failure … C Maack, M Lehrke, J Backs, FR Heinzel, JS Hulot, N Marx, WJ Paulus, ... European heart journal 39 (48), 4243-4254, 2018 | 248 | 2018 |
Proteomic remodelling of mitochondrial oxidative pathways in pressure overload-induced heart failure H Bugger, M Schwarzer, D Chen, A Schrepper, PA Amorim, M Schoepe, ... Cardiovascular research 85 (2), 376-384, 2010 | 246 | 2010 |
Type 1 diabetic akita mouse hearts are insulin sensitive but manifest structurally abnormal mitochondria that remain coupled despite increased uncoupling protein 3 H Bugger, S Boudina, XX Hu, J Tuinei, VG Zaha, HA Theobald, UJ Yun, ... Diabetes 57 (11), 2924-2932, 2008 | 213 | 2008 |
Tissue-specific remodeling of the mitochondrial proteome in type 1 diabetic akita mice H Bugger, D Chen, C Riehle, J Soto, HA Theobald, XX Hu, B Ganesan, ... Diabetes 58 (9), 1986-1997, 2009 | 209 | 2009 |
SIRT3 deficiency impairs mitochondrial and contractile function in the heart C Koentges, K Pfeil, T Schnick, S Wiese, R Dahlbock, MC Cimolai, ... Basic research in cardiology 110, 1-20, 2015 | 197 | 2015 |
Mechanistic Target of Rapamycin (Mtor) Is Essential for Murine Embryonic Heart Development and Growth Y Zhu, KMP Pires, KJ Whitehead, CD Olsen, B Wayment, YC Zhang, ... PloS one 8 (1), e54221, 2013 | 195 | 2013 |
PGC-1β deficiency accelerates the transition to heart failure in pressure overload hypertrophy C Riehle, AR Wende, VG Zaha, KM Pires, B Wayment, C Olsen, H Bugger, ... Circulation research 109 (7), 783-793, 2011 | 175 | 2011 |
Mitochondrial mechanisms in septic cardiomyopathy MC Cimolai, S Alvarez, C Bode, H Bugger International Journal of Molecular Sciences 16 (8), 17763-17778, 2015 | 144 | 2015 |
Empagliflozin protects heart from inflammation and energy depletion via AMPK activation CN Koyani, I Plastira, H Sourij, S Hallström, A Schmidt, PP Rainer, ... Pharmacological research 158, 104870, 2020 | 143 | 2020 |
Insulin receptor substrate signaling suppresses neonatal autophagy in the heart C Riehle, AR Wende, S Sena, KM Pires, RO Pereira, Y Zhu, H Bugger, ... The Journal of clinical investigation 123 (12), 5319-5333, 2013 | 127 | 2013 |