Synthesis and biological evaluation of structurally diverse 6-aryl-3-aroyl-indole analogues as inhibitors of tubulin polymerization W Ren, Y Deng, JD Ward, R Vairin, R Bai, HI Wanniarachchi, KB Hamal, ... European Journal of Medicinal Chemistry 263, 115794, 2024 | 10 | 2024 |
Structure Guided Design, Synthesis, and Biological Evaluation of Oxetane-Containing Indole Analogues W Ren, R Vairin, JD Ward, R Francis, J VanNatta, R Bai, PE Tankoano, ... Bioorganic & Medicinal Chemistry 92, 117400, 2023 | 2 | 2023 |
Drug-linker constructs bearing unique dual-mechanism tubulin binding payloads tethered through cleavable and non-cleavable linkers JW Ford, JM VanNatta, D Mondal, CM Lin, Y Deng, R Bai, E Hamel, ... Tetrahedron 171, 134350, 2025 | | 2025 |
Abstract 2086 Preliminary pharmacokinetic study of OXi8007, an effective vascular disrupting agent, in an orthotopic RENCA tumor-bearing BALB/c mouse model Y Deng, C Tamminga, K Hamal, C Pavlich, R Schuetze, H Wanniarachchi, ... Journal of Biological Chemistry 300 (3), 2024 | | 2024 |
Targeting anticancer agents to the tumor microenvironment with cathepsin B cleavable drug-linker conjugates of phosphatidylserine-binding proteins Y Deng, JW Ford, JM VanNatta, CJ Maguire, D Mondal, NZ Phinney, ... Cancer Research 83 (7_Supplement), 1545-1545, 2023 | | 2023 |
Discerning vasculature destruction caused by novel vascular disrupting agents examined by optical and multispectral optoacoustic imaging HI Wanniarachchi, R Schuetze, L Arango, K Hamal, GJ Carlson, C Pavlich, ... Cancer Research 82 (12_Supplement), 6206-6206, 2022 | | 2022 |
Release of Anticancer Agents in the Tumor Microenvironment Using Cathepsin B and Cathepsin L Cleavable Drug‐Linker Constructs Y Deng, J Ford, C Maguire, D Mondal, K Pinney, ML Trawick The FASEB Journal 35, 2021 | | 2021 |