Identification of polyoxometalates as nanomolar noncompetitive inhibitors of protein kinase CK2 R Prudent, V Moucadel, B Laudet, C Barette, L Lafanechère, ... Chemistry & biology 15 (7), 683-692, 2008 | 197 | 2008 |
New protein kinase CK2 inhibitors: jumping out of the catalytic box R Prudent, C Cochet Chemistry & biology 16 (2), 112-120, 2009 | 132 | 2009 |
Structure-based design of small peptide inhibitors of protein kinase CK2 subunit interaction B Laudet, C Barette, V Dulery, O Renaudet, P Dumy, A Metz, R Prudent, ... Biochemical Journal 408 (3), 363-373, 2007 | 113 | 2007 |
Functional analysis of the BMP9 response of ALK1 mutants from HHT2 patients: a diagnostic tool for novel ACVRL1 mutations N Ricard, M Bidart, C Mallet, G Lesca, S Giraud, R Prudent, JJ Feige, ... Blood, The Journal of the American Society of Hematology 116 (9), 1604-1612, 2010 | 97 | 2010 |
LIM kinases: cofilin and beyond C Prunier, R Prudent, R Kapur, K Sadoul, L Lafanechère Oncotarget 8 (25), 41749, 2017 | 94 | 2017 |
Antitumor activity of pyridocarbazole and benzopyridoindole derivatives that inhibit protein kinase CK2 R Prudent, V Moucadel, CH Nguyen, C Barette, F Schmidt, JC Florent, ... Cancer research 70 (23), 9865-9874, 2010 | 91 | 2010 |
Pharmacological inhibition of LIM kinase stabilizes microtubules and inhibits neoplastic growth R Prudent, E Vassal-Stermann, CH Nguyen, C Pillet, A Martinez, ... Cancer research 72 (17), 4429-4439, 2012 | 83 | 2012 |
Identification of chemical inhibitors of protein-kinase CK2 subunit interaction B Laudet, V Moucadel, R Prudent, O Filhol, YS Wong, D Royer, C Cochet Molecular and cellular biochemistry 316, 63-69, 2008 | 83 | 2008 |
New potent dual inhibitors of CK2 and Pim kinases: discovery and structural insights M López‐Ramos, R Prudent, V Moucadel, CF Sautel, C Barette, ... The FASEB Journal 24 (9), 3171-3185, 2010 | 75 | 2010 |
Structure-based discovery of small molecules targeting different surfaces of protein-kinase CK2 R Prudent, CF Sautel, C Cochet Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1804 (3), 493-498, 2010 | 67 | 2010 |
Exploring new targets and chemical space with affinity selection-mass spectrometry R Prudent, DA Annis, PJ Dandliker, JY Ortholand, D Roche Nature Reviews Chemistry 5 (1), 62-71, 2021 | 66 | 2021 |
Functional Analysis of Protein Kinase CK2 of the Human Malaria Parasite Plasmodium falciparum Z Holland, R Prudent, JB Reiser, C Cochet, C Doerig Eukaryotic cell 8 (3), 388-397, 2009 | 60 | 2009 |
Antitumoral activity of allosteric inhibitors of protein kinase CK2 V Moucadel, R Prudent, CF Sautel, F Teillet, C Barette, L Lafanechere, ... Oncotarget 2 (12), 997, 2011 | 52 | 2011 |
Expanding the chemical diversity of CK2 inhibitors R Prudent, V Moucadel, M López-Ramos, S Aci, B Laudet, L Mouawad, ... Molecular and cellular biochemistry 316, 71-85, 2008 | 45 | 2008 |
Azaindole derivatives are inhibitors of microtubule dynamics, with anti‐cancer and anti‐angiogenic activities R Prudent, É Vassal‐Stermann, CH Nguyen, M Mollaret, J Viallet, ... British journal of pharmacology 168 (3), 673-685, 2013 | 44 | 2013 |
LIM kinase inhibitor Pyr1 reduces the growth and metastatic load of breast cancers C Prunier, V Josserand, J Vollaire, E Beerling, C Petropoulos, O Destaing, ... Cancer Research 76 (12), 3541-3552, 2016 | 33 | 2016 |
Sulphamoylated 2-methoxyestradiol analogues induce apoptosis in adenocarcinoma cell lines M Visagie, A Theron, T Mqoco, W Vieira, R Prudent, A Martinez, ... PLoS One 8 (9), e71935, 2013 | 33 | 2013 |
Discovery of holoenzyme-disrupting chemicals as substrate-selective CK2 inhibitors I Kufareva, B Bestgen, P Brear, R Prudent, B Laudet, V Moucadel, ... Scientific reports 9 (1), 15893, 2019 | 22 | 2019 |
Novel in silico-designed estradiol analogues are cytotoxic to a multidrug-resistant cell line at nanomolar concentrations A Theron, R Prudent, E Nolte, I van den Bout, R Punchoo, S Marais, ... Cancer chemotherapy and pharmacology 75, 431-437, 2015 | 17 | 2015 |
Phosphorylation of the C subunit (p66) of human DNA polymerase δ L Lemmens, S Urbach, R Prudent, C Cochet, G Baldacci, P Hughes Biochemical and biophysical research communications 367 (2), 264-270, 2008 | 17 | 2008 |