How nascent phagosomes mature to become phagolysosomes GD Fairn, S Grinstein Trends in immunology 33 (8), 397-405, 2012 | 317 | 2012 |
High-resolution mapping reveals topologically distinct cellular pools of phosphatidylserine GD Fairn, NL Schieber, N Ariotti, S Murphy, L Kuerschner, RI Webb, ... Journal of Cell Biology 194 (2), 257-275, 2011 | 312 | 2011 |
VAPs and ACBD5 tether peroxisomes to the ER for peroxisome maintenance and lipid homeostasis R Hua, D Cheng, É Coyaud, S Freeman, E Di Pietro, Y Wang, A Vissa, ... Journal of Cell Biology 216 (2), 367-377, 2017 | 258 | 2017 |
Complementary probes reveal that phosphatidylserine is required for the proper transbilayer distribution of cholesterol M Maekawa, GD Fairn Journal of cell science 128 (7), 1422-1433, 2015 | 234 | 2015 |
Phosphoinositide 3-kinase enables phagocytosis of large particles by terminating actin assembly through Rac/Cdc42 GTPase-activating proteins D Schlam, RD Bagshaw, SA Freeman, RF Collins, T Pawson, GD Fairn, ... Nature communications 6 (1), 8623, 2015 | 218 | 2015 |
Phosphatidylserine is polarized and required for proper Cdc42 localization and for development of cell polarity GD Fairn, M Hermansson, P Somerharju, S Grinstein Nature cell biology 13 (12), 1424-1430, 2011 | 210 | 2011 |
Phospholipid subcellular localization and dynamics Y Yang, M Lee, GD Fairn Journal of Biological Chemistry 293 (17), 6230-6240, 2018 | 188 | 2018 |
PI(4,5)P2 controls plasma membrane PI4P and PS levels via ORP5/8 recruitment to ER–PM contact sites M Sohn, M Korzeniowski, JP Zewe, RC Wills, GRV Hammond, ... Journal of Cell Biology 217 (5), 1797-1813, 2018 | 168 | 2018 |
Contribution of phosphatidylserine to membrane surface charge and protein targeting during phagosome maturation T Yeung, B Heit, JF Dubuisson, GD Fairn, B Chiu, R Inman, A Kapus, ... Journal of Cell Biology 185 (5), 917-928, 2009 | 151 | 2009 |
Transcellular vesicular transport in epithelial and endothelial cells: Challenges and opportunities KYY Fung, GD Fairn, WL Lee Traffic 19 (1), 5-18, 2018 | 147 | 2018 |
Cleavage furrow organization requires PIP2-mediated recruitment of anillin J Liu, GD Fairn, DF Ceccarelli, F Sicheri, A Wilde Current biology 22 (1), 64-69, 2012 | 143 | 2012 |
Palmitoylation of NOD1 and NOD2 is required for bacterial sensing Y Lu, Y Zheng, É Coyaud, C Zhang, A Selvabaskaran, Y Yu, Z Xu, ... Science 366 (6464), 460-467, 2019 | 124 | 2019 |
SR-BI mediated transcytosis of HDL in brain microvascular endothelial cells is independent of caveolin, clathrin, and PDZK1 KY Fung, C Wang, S Nyegaard, B Heit, GD Fairn, WL Lee Frontiers in physiology 8, 841, 2017 | 124 | 2017 |
The oxysterol binding protein Kes1p regulates Golgi apparatus phosphatidylinositol-4-phosphate function GD Fairn, AJ Curwin, CJ Stefan, CR McMaster Proceedings of the National Academy of Sciences 104 (39), 15352-15357, 2007 | 121 | 2007 |
Phosphatidic acid is required for the constitutive ruffling and macropinocytosis of phagocytes M Bohdanowicz, D Schlam, M Hermansson, D Rizzuti, GD Fairn, ... Molecular biology of the cell 24 (11), 1700-1712, 2013 | 117 | 2013 |
Molecular probes to visualize the location, organization and dynamics of lipids M Maekawa, GD Fairn Journal of cell science 127 (22), 4801-4812, 2014 | 116 | 2014 |
Inhibition of acid sphingomyelinase depletes cellular phosphatidylserine and mislocalizes K-Ras from the plasma membrane K Cho, D van der Hoeven, Y Zhou, M Maekawa, X Ma, W Chen, GD Fairn, ... Molecular and cellular biology 36 (2), 363-374, 2016 | 113 | 2016 |
Akt-ing up just about everywhere: compartment-specific Akt activation and function in receptor tyrosine kinase signaling MG Sugiyama, GD Fairn, CN Antonescu Frontiers in Cell and Developmental Biology 7, 70, 2019 | 110 | 2019 |
Distribution, dynamics and functional roles of phosphatidylserine within the cell JG Kay, GD Fairn Cell Communication and Signaling 17 (1), 126, 2019 | 103 | 2019 |
An electrostatic switch displaces phosphatidylinositol phosphate kinases from the membrane during phagocytosis GD Fairn, K Ogata, RJ Botelho, PD Stahl, RA Anderson, P De Camilli, ... Journal of Cell Biology 187 (5), 701-714, 2009 | 101 | 2009 |