TREM2 maintains microglial metabolic fitness in Alzheimer’s disease TK Ulland, WM Song, SCC Huang, JD Ulrich, A Sergushichev, WL Beatty, ... Cell 170 (4), 649-663. e13, 2017 | 927 | 2017 |
Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer’s disease Y Zhou, WM Song, PS Andhey, A Swain, T Levy, KR Miller, PL Poliani, ... Nature medicine 26 (1), 131-142, 2020 | 755 | 2020 |
ApoE facilitates the microglial response to amyloid plaque pathology JD Ulrich, TK Ulland, TE Mahan, S Nyström, KP Nilsson, WM Song, ... Journal of Experimental Medicine 215 (4), 1047-1058, 2018 | 236 | 2018 |
Humanized TREM2 mice reveal microglia-intrinsic and-extrinsic effects of R47H polymorphism WM Song, S Joshita, Y Zhou, TK Ulland, S Gilfillan, M Colonna Journal of Experimental Medicine 215 (3), 745-760, 2018 | 229 | 2018 |
TREM2 sustains macrophage-hepatocyte metabolic coordination in nonalcoholic fatty liver disease and sepsis J Hou, J Zhang, P Cui, Y Zhou, C Liu, X Wu, Y Ji, S Wang, B Cheng, H Ye, ... The Journal of clinical investigation 131 (4), 2021 | 138 | 2021 |
TREM2 drives microglia response to amyloid-β via SYK-dependent and-independent pathways S Wang, R Sudan, V Peng, Y Zhou, S Du, CM Yuede, T Lei, J Hou, Z Cai, ... Cell 185 (22), 4153-4169. e19, 2022 | 129 | 2022 |
High‐affinity interactions and signal transduction between Aβ oligomers and TREM 2 CB Lessard, SL Malnik, Y Zhou, TB Ladd, PE Cruz, Y Ran, TE Mahan, ... EMBO molecular medicine 10 (11), e9027, 2018 | 108 | 2018 |
TREM2-dependent effects on microglia in Alzheimer’s disease Y Zhou, TK Ulland, M Colonna Frontiers in Aging Neuroscience 10, 202, 2018 | 81 | 2018 |
Profiling senescent cells in human brains reveals neurons with CDKN2D/p19 and tau neuropathology SK Dehkordi, J Walker, E Sah, E Bennett, F Atrian, B Frost, B Woost, ... Nature aging 1 (12), 1107-1116, 2021 | 66 | 2021 |
Brain parenchymal and extraparenchymal macrophages in development, homeostasis, and disease S Brioschi, Y Zhou, M Colonna The Journal of Immunology 204 (2), 294-305, 2020 | 50 | 2020 |
Transcriptomic atlas and interaction networks of brain cells in mouse CNS demyelination and remyelination J Hou, Y Zhou, Z Cai, M Terekhova, A Swain, PS Andhey, RM Guimaraes, ... Cell reports 42 (4), 2023 | 20 | 2023 |
Human early-onset dementia caused by DAP12 deficiency reveals a unique signature of dysregulated microglia Y Zhou, M Tada, Z Cai, PS Andhey, A Swain, KR Miller, S Gilfillan, ... Nature immunology 24 (3), 545-557, 2023 | 16 | 2023 |
Antibody-mediated targeting of human microglial leukocyte Ig-like receptor B4 attenuates amyloid pathology in a mouse model J Hou, Y Chen, Z Cai, GS Heo, CM Yuede, Z Wang, K Lin, F Saadi, ... Science Translational Medicine 16 (741), eadj9052, 2024 | | 2024 |