Cystic fibrosis: insight into CFTR pathophysiology and pharmacotherapy B Lubamba, B Dhooghe, S Noel, T Leal Clinical biochemistry 45 (15), 1132-1144, 2012 | 212 | 2012 |
Lung inflammation in cystic fibrosis: pathogenesis and novel therapies B Dhooghe, S Noël, F Huaux, T Leal Clinical biochemistry 47 (7-8), 539-546, 2014 | 73 | 2014 |
Dysregulated proinflammatory and fibrogenic phenotype of fibroblasts in cystic fibrosis F Huaux, S Noel, B Dhooghe, N Panin, S Lo Re, D Lison, P Wallemacq, ... PloS one 8 (5), e64341, 2013 | 42 | 2013 |
PDE5 inhibitors as potential tools in the treatment of cystic fibrosis S Noel, B Dhooghe, T Leal Frontiers in pharmacology 3, 167, 2012 | 41 | 2012 |
Immunomodulatory activity of vardenafil on induced lung inflammation in cystic fibrosis mice B Lubamba, F Huaux, J Lebacq, E Marbaix, B Dhooghe, N Panin, ... Journal of Cystic Fibrosis 11 (4), 266-273, 2012 | 30 | 2012 |
Strategies in early clinical development for the treatment of basic defects of cystic fibrosis B Dhooghe, JB Haaf, S Noel, T Leal Expert Opinion on Investigational Drugs 25 (4), 423-436, 2016 | 29 | 2016 |
Correction of chloride transport and mislocalization of CFTR protein by vardenafil in the gastrointestinal tract of cystic fibrosis mice B Dhooghe, S Noël, C Bouzin, G Behets-Wydemans, T Leal PLoS One 8 (10), e77314, 2013 | 25 | 2013 |
Efficacy of vedolizumab for induction of clinical response and remission in patients with moderate to severe inflammatory bowel disease who failed at least two TNF antagonists M De Vos, B Dhooghe, S Vermeire, E Louis, F Mana, A Elewaut, ... United European gastroenterology journal 6 (3), 439-445, 2018 | 20 | 2018 |
Resveratrol increases F508del-CFTR dependent salivary secretion in cystic fibrosis mice B Dhooghe, C Bouckaert, A Capron, P Wallemacq, T Leal, S Noel Biology Open 4 (7), 929-936, 2015 | 19 | 2015 |
Vardenafil reduces macrophage pro-inflammatory overresponses in cystic fibrosis through PDE5-and CFTR-dependent mechanisms S Noel, N Panin, M Beka, B Dhooghe, F Huaux, T Leal Clinical Science 131 (11), 1107-1121, 2017 | 16 | 2017 |
Comparative variability of nasal potential difference measurements in human and mice A Leonard, B Lubamba, B Dhooghe, S Noel, P Wallemacq, P Lebecque, ... Open Journal of Respiratory Diseases 2 (02), 43, 2012 | 13 | 2012 |
Azithromycin Attenuates Pseudomonas-Induced Lung Inflammation by Targeting Bacterial Proteins Secreted in the Cultured Medium T Leal, G Bergamini, F Huaux, N Panin, S Noel, B Dhooghe, JB Haaf, ... Frontiers in immunology 7, 499, 2016 | 7 | 2016 |
Belgian Inflammatory Bowel Disease Research and Development (BIRD) M De Vos, B Dhooghe, S Vermeire Efficacy of vedolizumab for induction of clinical response and remission in …, 2018 | 6 | 2018 |
Pharmacological Potential of PDE5 Inhibitors for the Treatment of Cystic Fibrosis B Lubamba, B Dhooghe, S Noël, T Leal Cystic Fibrosis - Renewed hopes through research", 2012 | 3 | 2012 |
Vardenafil increases intracellular accumulation of the most prevalent mutant cystic fibrosis transmembrane conductance regulator (CTFR) in human bronchial epithelial cells B Dhooghe, C Bouzin, A Mottais, E Hermans, M Delion, N Panin, S Noel, ... Biology Open 9 (8), bio053116, 2020 | 1 | 2020 |
19 Performing the Stanford beta-sweat test using non-invasive drug delivery P Viphonephom, B Dhooghe, S Noel, P Melotti, F Vermeulen, K De Boeck, ... Journal of Cystic Fibrosis 1 (15), S56, 2016 | 1 | 2016 |
35 Deficiency of the Planar Cell Polarity protein CELSR3 in CF bronchial epithelial cells increases susceptibility to epithelial–mesenchymal transition S Noel, B Dhooghe, A Dykmans, W Delbart, T Leal Journal of Cystic Fibrosis 14, S65, 2015 | 1 | 2015 |
Comparative variability of nasal potential difference measurements in human and mice, healthy or carrying two severe CFTR mutations A Leonard, B Lubamba, B Dhooghe, S Noel, P Wallemacq, P Lebecque, ... 35th European Cystic Fibrosis Conference (Dublin, Ireland), vol.11, no.1 …, 2012 | 1 | 2012 |
Resveratrol improves chloride secretion in cystic fibrosis mice homozygous for the F508del mutation A Palem, C Bouckaert, B Dhooghe, A Leonard, B Lubamba, P Wallemacq, ... 34th European Cystic Fibrosis Conference (Hamburg, Germany) 10, 2011 | 1 | 2011 |
De invoering van het alcoholslot in België: literatuurstudie over de effectiviteit B Dhooghe, A Verstraete Tijdschrift voor geneeskunde 67 (8), 367-371, 2011 | 1 | 2011 |