The nuclear RNase III Drosha initiates microRNA processing Y Lee, C Ahn, J Han, H Choi, J Kim, J Yim, J Lee, P Provost, O Rådmark, ... Nature 425 (6956), 415-419, 2003 | 7442 | 2003 |
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice JP Friedmann Angeli, M Schneider, B Proneth, YY Tyurina, VA Tyurin, ... Nature cell biology 16 (12), 1180-1191, 2014 | 2842 | 2014 |
Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent-and AIF-mediated cell death A Seiler, M Schneider, H Förster, S Roth, EK Wirth, C Culmsee, N Plesnila, ... Cell metabolism 8 (3), 237-248, 2008 | 1353 | 2008 |
Ribonuclease activity and RNA binding of recombinant human Dicer P Provost, D Dishart, J Doucet, D Frendewey, B Samuelsson, O Rådmark The EMBO journal, 2002 | 672 | 2002 |
Expanding expression of the 5-lipoxygenase pathway within the arterial wall during human atherogenesis R Spanbroek, R Gräbner, K Lötzer, M Hildner, A Urbach, K Rühling, ... Proceedings of the National Academy of Sciences 100 (3), 1238-1243, 2003 | 632 | 2003 |
5-Lipoxygenase: regulation of expression and enzyme activity O Rådmark, O Werz, D Steinhilber, B Samuelsson Trends in biochemical sciences 32 (7), 332-341, 2007 | 563 | 2007 |
Leukotriene B4 is a potent and stereospecific stimulator of neutrophil chemotaxis and adherence J Palmblad, CL Malmsten, AM Udén, O Rådmark, L Engstedt, ... Blood 58 (3), 658-661, 1981 | 530 | 1981 |
5-Lipoxygenase, a key enzyme for leukotriene biosynthesis in health and disease O Rådmark, O Werz, D Steinhilber, B Samuelsson Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2015 | 511 | 2015 |
Enzyme with dual lipoxygenase activities catalyzes leukotriene A4 synthesis from arachidonic acid. T Shimizu, O Rådmark, B Samuelsson Proceedings of the National Academy of Sciences 81 (3), 689-693, 1984 | 421 | 1984 |
Leukotriene A4 hydrolase in human leukocytes. Purification and properties. O Rådmark, T Shimizu, H Jörnvall, B Samuelsson Journal of Biological Chemistry 259 (20), 12339-12345, 1984 | 340 | 1984 |
Molecular cloning and amino acid sequence of human 5-lipoxygenase. T Matsumoto, CD Funk, O Rådmark, JO Höög, H Jörnvall, B Samuelsson Proceedings of the National Academy of Sciences 85 (1), 26-30, 1988 | 299 | 1988 |
Thromboxane generation by human peripheral blood polymorphonuclear leukocytes. IM Goldstein, CL Malmsten, H Kindahl, HB Kaplan, O Rådmark, ... The Journal of experimental medicine 148 (3), 787-792, 1978 | 290 | 1978 |
5-lipoxygenase is phosphorylated by p38 kinase-dependent MAPKAP kinases O Werz, J Klemm, B Samuelsson, O Rådmark Proceedings of the National Academy of Sciences 97 (10), 5261-5266, 2000 | 286 | 2000 |
Exosomes from human macrophages and dendritic cells contain enzymes for leukotriene biosynthesis and promote granulocyte migration J Esser, U Gehrmann, FL D'Alexandri, AM Hidalgo-Estévez, CE Wheelock, ... Journal of Allergy and Clinical Immunology 126 (5), 1032-1040. e4, 2010 | 282 | 2010 |
The N-terminal domain of 5-lipoxygenase binds calcium and mediates calcium stimulation of enzyme activity T Hammarberg, P Provost, B Persson, O Rådmark Journal of Biological Chemistry 275 (49), 38787-38793, 2000 | 243 | 2000 |
Activation of 5-lipoxygenase by cell stress is calcium independent in human polymorphonuclear leukocytes O Werz, E Bürkert, B Samuelsson, O Rådmark, D Steinhilber Blood, The Journal of the American Society of Hematology 99 (3), 1044-1052, 2002 | 234 | 2002 |
Characterization of leukotriene A4 synthase from murine mast cells: evidence for its identity to arachidonate 5-lipoxygenase. T Shimizu, T Izumi, Y Seyama, K Tadokoro, O Rådmark, B Samuelsson Proceedings of the National Academy of Sciences 83 (12), 4175-4179, 1986 | 233 | 1986 |
5-Lipoxygenase: mechanisms of regulation1 O Rådmark, B Samuelsson Journal of lipid research 50, S40-S45, 2009 | 225 | 2009 |
ERK-mediated regulation of leukotriene biosynthesis by androgens: a molecular basis for gender differences in inflammation and asthma C Pergola, G Dodt, A Rossi, E Neunhoeffer, B Lawrenz, H Northoff, ... Proceedings of the National Academy of Sciences 105 (50), 19881-19886, 2008 | 220 | 2008 |
Bronchoalveolar lavage fluid exosomes contribute to cytokine and leukotriene production in allergic asthma P Torregrosa Paredes, J Esser, C Admyre, M Nord, QK Rahman, A Lukic, ... Allergy 67 (7), 911-919, 2012 | 213 | 2012 |