| Squalene epoxidase drives NAFLD-induced hepatocellular carcinoma and is a pharmaceutical target D Liu, CC Wong, L Fu, H Chen, L Zhao, C Li, Y Zhou, Y Zhang, W Xu, ... Science translational medicine 10 (437), eaap9840, 2018 | 223 | 2018 |
| RNA N6-methyladenosine methyltransferase METTL3 facilitates colorectal cancer by activating the m6A-GLUT1-mTORC1 axis and is a therapeutic target H Chen, S Gao, W Liu, CC Wong, J Wu, J Wu, D Liu, H Gou, W Kang, ... Gastroenterology 160 (4), 1284-1300. e16, 2021 | 204 | 2021 |
| SARS-CoV-2 non-structural protein 6 triggers NLRP3-dependent pyroptosis by targeting ATP6AP1 X Sun, Y Liu, Z Huang, W Xu, W Hu, L Yi, Z Liu, H Chan, J Zeng, X Liu, ... Cell Death & Differentiation 29 (6), 1240-1254, 2022 | 128 | 2022 |
| MicroRNA-9 up-regulation is involved in colorectal cancer metastasis via promoting cell motility L Zhu, H Chen, D Zhou, D Li, R Bai, S Zheng, W Ge Medical oncology 29, 1037-1043, 2012 | 127 | 2012 |
| METTL3 inhibits antitumor immunity by targeting m6A-BHLHE41-CXCL1/CXCR2 axis to promote colorectal cancer H Chen, Y Pan, Q Zhou, C Liang, CC Wong, Y Zhou, D Huang, W Liu, ... Gastroenterology 163 (4), 891-907, 2022 | 124 | 2022 |
| SLC25A22 promotes proliferation and survival of colorectal cancer cells with KRAS mutations and xenograft tumor progression in mice via intracellular synthesis of aspartate CC Wong, Y Qian, X Li, J Xu, W Kang, JH Tong, KF To, Y Jin, W Li, ... Gastroenterology 151 (5), 945-960. e6, 2016 | 114 | 2016 |
| N6-methyladenosine reader YTHDF1 promotes ARHGEF2 translation and RhoA signaling in colorectal cancer S Wang, S Gao, Y Zeng, L Zhu, Y Mo, CC Wong, Y Bao, P Su, J Zhai, ... Gastroenterology 162 (4), 1183-1196, 2022 | 112 | 2022 |
| In colorectal cancer cells with mutant KRAS, SLC25A22-mediated glutaminolysis reduces DNA demethylation to increase WNT signaling, stemness, and drug resistance CC Wong, J Xu, X Bian, JL Wu, W Kang, Y Qian, W Li, H Chen, H Gou, ... Gastroenterology 159 (6), 2163-2180. e6, 2020 | 103 | 2020 |
| Microbial community heterogeneity within colorectal neoplasia and its correlation with colorectal carcinogenesis W Liu, X Zhang, H Xu, S Li, HCH Lau, Q Chen, B Zhang, L Zhao, H Chen, ... Gastroenterology 160 (7), 2395-2408, 2021 | 93 | 2021 |
| A retrospective study of pyogenic liver abscess focusing on Klebsiella pneumoniae as a primary pathogen in China from 1994 to 2015 Y Qian, CC Wong, S Lai, H Chen, X He, L Sun, J Wu, J Zhou, J Yu, W Liu, ... Scientific reports 6 (1), 38587, 2016 | 78 | 2016 |
| OLA1 protects cells in heat shock by stabilizing HSP70 RF Mao, V Rubio, H Chen, L Bai, OC Mansour, ZZ Shi Cell death & disease 4 (2), e491-e491, 2013 | 71 | 2013 |
| Targeting m6A reader YTHDF1 augments antitumour immunity and boosts anti-PD-1 efficacy in colorectal cancer Y Bao, J Zhai, H Chen, CC Wong, C Liang, Y Ding, D Huang, H Gou, ... Gut 72 (8), 1497-1509, 2023 | 68 | 2023 |
| SARS-CoV-2 activates lung epithelial cell proinflammatory signaling and leads to immune dysregulation in COVID-19 patients H Chen, W Liu, Y Wang, D Liu, L Zhao, J Yu EBioMedicine 70, 2021 | 66 | 2021 |
| A seven-gene signature predicts overall survival of patients with colorectal cancer H Chen, X Sun, W Ge, Y Qian, R Bai, S Zheng Oncotarget 8 (56), 95054, 2017 | 65 | 2017 |
| Sodium channel subunit SCNN1B suppresses gastric cancer growth and metastasis via GRP78 degradation Y Qian, CC Wong, J Xu, H Chen, Y Zhang, W Kang, H Wang, L Zhang, ... Cancer research 77 (8), 1968-1982, 2017 | 61 | 2017 |
| CAB39L elicited an anti-Warburg effect via a LKB1-AMPK-PGC1α axis to inhibit gastric tumorigenesis W Li, CC Wong, X Zhang, W Kang, G Nakatsu, Q Zhao, H Chen, MYY Go, ... Oncogene 37 (50), 6383-6398, 2018 | 60 | 2018 |
| Loss of YTHDF1 in gastric tumors restores sensitivity to antitumor immunity by recruiting mature dendritic cells X Bai, CC Wong, Y Pan, H Chen, W Liu, J Zhai, W Kang, Y Shi, ... Journal for immunotherapy of cancer 10 (2), 2022 | 58 | 2022 |
| APLN promotes hepatocellular carcinoma through activating PI3K/Akt pathway and is a druggable target H Chen, CC Wong, D Liu, MYY Go, B Wu, S Peng, M Kuang, N Wong, ... Theranostics 9 (18), 5246, 2019 | 58 | 2019 |
| CRISPR screens identify cholesterol biosynthesis as a therapeutic target on stemness and drug resistance of colon cancer S Gao, F Soares, S Wang, CC Wong, H Chen, Z Yang, W Liu, MYY Go, ... Oncogene 40 (48), 6601-6613, 2021 | 54 | 2021 |
| DEAD-box helicase 27 promotes colorectal cancer growth and metastasis and predicts poor survival in CRC patients J Tang, H Chen, CC Wong, D Liu, T Li, X Wang, J Ji, JJY Sung, JY Fang, ... Oncogene 37 (22), 3006-3021, 2018 | 54 | 2018 |
