| Discovery of Risdiplam, a Selective Survival of Motor Neuron-2 (SMN2) Gene Splicing Modifier for the Treatment of Spinal Muscular Atrophy (SMA) H Ratni, M Ebeling, J Baird, S Bendels, J Bylund, KS Chen, N Denk, ... Journal of Medicinal Chemistry 61 (15), 6501-6517, 2018 | 480 | 2018 |
| Analysis of cytochrome P450 metabolites of arachidonic and linoleic acids by liquid chromatography–mass spectrometry with ion trap MS2 J Bylund, J Ericsson, EH Oliw Analytical biochemistry 265 (1), 55-68, 1998 | 163 | 1998 |
| Cytochromes P450 with bisallylic hydroxylation activity on arachidonic and linoleic acids studied with human recombinant enzymes and with human and rat liver microsomes J Bylund, T Kunz, K Valmsen, EH Oliw Journal of Pharmacology and Experimental Therapeutics 284 (1), 51-60, 1998 | 122 | 1998 |
| cDna cloning and expression of CYP4F12, a novel human cytochrome P450 J Bylund, M Bylund, EH Oliw Biochemical and biophysical research communications 280 (3), 892-897, 2001 | 114 | 2001 |
| Identification of CYP4F8 in human seminal vesicles as a prominent 19-hydroxylase of prostaglandin endoperoxides J Bylund, M Hidestrand, M Ingelman-Sundberg, EH Oliw Journal of Biological Chemistry 275 (29), 21844-21849, 2000 | 107 | 2000 |
| Practical use of the regression offset approach for the prediction of in vivo intrinsic clearance from hepatocytes AK Sohlenius-Sternbeck, C Jones, D Ferguson, BJ Middleton, D Projean, ... Xenobiotica 42 (9), 841-853, 2012 | 100 | 2012 |
| Metabotropic glutamate receptor activation enhances the activities of two types of Ca2+-activated K+ channels in rat hippocampal astrocytes D Gebremedhin, K Yamaura, C Zhang, J Bylund, RC Koehler, DR Harder Journal of Neuroscience 23 (5), 1678-1687, 2003 | 99 | 2003 |
| Bisallylic hydroxylation and epoxidation of polyunsaturated fatty acids by cytochrome P450 EH Oliw, J Bylund, C Herman Lipids 31 (10), 1003-1021, 1996 | 69 | 1996 |
| Gene expression of a novel cytochrome P450 of the CYP4F subfamily in human seminal vesicles J Bylund, N Finnström, EH Oliw Biochemical and biophysical research communications 261 (1), 169-174, 1999 | 68 | 1999 |
| Identification of a novel cytochrome P450, CYP4X1, with unique localization specific to the brain J Bylund, C Zhang, DR Harder Biochemical and biophysical research communications 296 (3), 677-684, 2002 | 62 | 2002 |
| Amyloid-PET predicts inhibition of de novo plaque formation upon chronic γ-secretase modulator treatment M Brendel, A Jaworska, J Herms, J Trambauer, C Roetzer, FJ Gildehaus, ... Molecular psychiatry 20 (10), 1179-1187, 2015 | 60 | 2015 |
| The impact of solute carrier (SLC) drug uptake transporter loss in human and rat cryopreserved hepatocytes on clearance predictions P Lundquist, J Lööf, AK Sohlenius-Sternbeck, E Floby, J Johansson, ... Drug Metabolism and Disposition 42 (3), 469-480, 2014 | 45 | 2014 |
| Leukotriene B4 ω-side chain hydroxylation by CYP4F5 and CYP4F6 J Bylund, AG Harder, KG Maier, RJ Roman, DR Harder Archives of biochemistry and biophysics 412 (1), 34-41, 2003 | 33 | 2003 |
| Oxidation of prostaglandin H2 and prostaglandin H2 analogues by human cytochromes P450: Analysis of ω-side chain hydroxy metabolites and four steroisomers of 5 … EH Oliw, K Stark, J Bylund Biochemical pharmacology 62 (4), 407-415, 2001 | 32 | 2001 |
| Dexamethasone induces bisallylic hydroxylation of polyunsaturated fatty acids by rat liver microsomes L Hörnsten, J Bylund, EH Oliw Archives of biochemistry and biophysics 332 (2), 261-268, 1996 | 25 | 1996 |
| Discovery of novel pyrrolopyridazine scaffolds as transient receptor potential vanilloid (TRPV1) antagonists I Dorange, R Forsblom, I Macsari, M Svensson, J Bylund, Y Besidski, ... Bioorganic & medicinal chemistry letters 22 (22), 6888-6895, 2012 | 21 | 2012 |
| Rat poorly predicts the combined non-absorbed and presystemically metabolized fractions in the human T Bueters, S Juric, AK Sohlenius-Sternbeck, Y Hu, J Bylund Xenobiotica 43 (7), 607-616, 2013 | 19 | 2013 |
| Exploration and pharmacokinetic profiling of phenylalanine based carbamates as novel substance p 1–7 analogues R Fransson, G Nordvall, J Bylund, A Carlsson-Jonsson, JM Kratz, ... ACS medicinal chemistry letters 5 (12), 1272-1277, 2014 | 17 | 2014 |
| Cloning and characterization of CYP4F21: a prostaglandin E2 20-hydroxylase of ram seminal vesicles J Bylund, EH Oliw Archives of Biochemistry and Biophysics 389 (1), 123-129, 2001 | 17 | 2001 |
| Phenyl isoxazole voltage-gated sodium channel blockers: Structure and activity relationship I Macsari, L Sandberg, Y Besidski, Y Gravenfors, T Ginman, J Bylund, ... Bioorganic & medicinal chemistry letters 21 (13), 3871-3876, 2011 | 16 | 2011 |
