Cell stress in cortical organoids impairs molecular subtype specification A Bhaduri, MG Andrews, W Mancia Leon, D Jung, D Shin, D Allen, D Jung, ... Nature 578 (7793), 142-148, 2020 | 491 | 2020 |
Channelopathy pathogenesis in autism spectrum disorders G Schmunk, JJ Gargus Frontiers in genetics 4, 61900, 2013 | 123 | 2013 |
Human microglia states are conserved across experimental models and regulate neural stem cell responses in chimeric organoids G Popova, SS Soliman, CN Kim, MG Keefe, KM Hennick, S Jain, T Li, ... Cell stem cell 28 (12), 2153-2166. e6, 2021 | 117 | 2021 |
Selective Kv1. 3 channel blocker as therapeutic for obesity and insulin resistance SK Upadhyay, KL Eckel-Mahan, MR Mirbolooki, I Tjong, SM Griffey, ... Proceedings of the National Academy of Sciences 110 (24), E2239-E2248, 2013 | 108 | 2013 |
Glioblastoma remodelling of human neural circuits decreases survival S Krishna, A Choudhury, MB Keough, K Seo, L Ni, S Kakaizada, A Lee, ... Nature 617 (7961), 599-607, 2023 | 107 | 2023 |
Parallel in vivo analysis of large-effect autism genes implicates cortical neurogenesis and estrogen in risk and resilience HR Willsey, CRT Exner, Y Xu, A Everitt, N Sun, B Wang, J Dea, ... Neuron 109 (5), 788-804. e8, 2021 | 95 | 2021 |
Intracellular calcium dysregulation in autism spectrum disorder: an analysis of converging organelle signaling pathways RL Nguyen, YV Medvedeva, TE Ayyagari, G Schmunk, JJ Gargus Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1865 (11), 1718-1732, 2018 | 72 | 2018 |
High-throughput screen detects calcium signaling dysfunction in typical sporadic autism spectrum disorder G Schmunk, RL Nguyen, DL Ferguson, K Kumar, I Parker, JJ Gargus Scientific reports 7 (1), 40740, 2017 | 41 | 2017 |
Automated four-dimensional long term imaging enables single cell tracking within organotypic brain slices to study neurodevelopment and degeneration JW Linsley, A Tripathi, I Epstein, G Schmunk, E Mount, M Campioni, ... Communications biology 2 (1), 155, 2019 | 39 | 2019 |
Shared functional defect in IP 3 R-mediated calcium signaling in diverse monogenic autism syndromes G Schmunk, BJ Boubion, IF Smith, I Parker, JJ Gargus Translational psychiatry 5 (9), e643-e643, 2015 | 39 | 2015 |
Intracellular trafficking of the KV1. 3 potassium channel is regulated by the prodomain of a matrix metalloprotease HM Nguyen, CA Galea, G Schmunk, BJ Smith, RA Edwards, RS Norton, ... Journal of Biological Chemistry 288 (9), 6451-6464, 2013 | 30 | 2013 |
DynaMorph: self-supervised learning of morphodynamic states of live cells Z Wu, BB Chhun, G Popova, SM Guo, CN Kim, LH Yeh, T Nowakowski, ... Molecular Biology of the Cell 33 (6), ar59, 2022 | 28* | 2022 |
Microglial GPR56 is the molecular target of maternal immune activation-induced parvalbumin-positive interneuron deficits D Yu, T Li, JC Delpech, B Zhu, P Kishore, T Koshi, R Luo, KJB Pratt, ... Science Advances 8 (18), eabm2545, 2022 | 22 | 2022 |
Optimal trade-off control in machine learning–based library design, with application to adeno-associated virus (AAV) for gene therapy D Zhu, DH Brookes, A Busia, A Carneiro, C Fannjiang, G Popova, D Shin, ... Science Advances 10 (4), eadj3786, 2024 | 17 | 2024 |
Human microglia upregulate cytokine signatures and accelerate maturation of neural networks G Schmunk, CN Kim, SS Soliman, MG Keefe, D Bogdanoff, D Tejera, ... bioRxiv, 2020.03. 24.006874, 2020 | 15 | 2020 |
Machine learning-based library design improves packaging and diversity of adeno-associated virus (AAV) libraries D Zhu, DH Brookes, A Busia, A Carneiro, C Fannjiang, G Popova, D Shin, ... bioRxiv, 2021.11. 02.467003, 2021 | 10 | 2021 |
Rubella virus tropism and single-cell responses in human primary tissue and microglia-containing organoids. G Popova, H Retallack, C Kim, A Wang, D Shin, J Derisi, T Nowakowski eLife, 2023 | 9 | 2023 |
Dysregulation of Neurogenic Calcium Signaling and Autism JJ Gargus, G Schmunk Comprehensive Guide to Autism. New York (NY): Springer New York, 1285-312, 2014 | 6 | 2014 |
Thalamocortical organoids enable in vitro modeling of 22q11. 2 microdeletion associated with neuropsychiatric disorders D Shin, CN Kim, J Ross, KM Hennick, SR Wu, N Paranjape, R Leonard, ... Cell Stem Cell, 2024 | 3 | 2024 |
NEURONAL ORIGIN INFLUENCES SPONTANEOUS NETWORK ACTIVITY IN GLIOBLASTOMA-NEURON COCULTURES A Daniel, S Krishna, G Popova, J Kaur, SL Hervey-Jumper NEURO-ONCOLOGY 24, 27-27, 2022 | | 2022 |