Secondary metabolism in the lichen symbiosis MJ Calcott, DF Ackerley, A Knight, RA Keyzers, JG Owen Chemical Society Reviews 47 (5), 1730-1760, 2018 | 241 | 2018 |
Structural, functional and evolutionary perspectives on effective re-engineering of non-ribosomal peptide synthetase assembly lines AS Brown, MJ Calcott, JG Owen, DF Ackerley Natural product reports 35 (11), 1210-1228, 2018 | 93 | 2018 |
Biosynthesis of novel pyoverdines by domain substitution in a nonribosomal peptide synthetase of Pseudomonas aeruginosa MJ Calcott, JG Owen, IL Lamont, DF Ackerley Applied and environmental microbiology 80 (18), 5723-5731, 2014 | 87 | 2014 |
Efficient rational modification of non-ribosomal peptides by adenylation domain substitution M Calcott, J Owen, D Ackerley Nature Communications 11, 2020 | 84 | 2020 |
Genetic manipulation of non-ribosomal peptide synthetases to generate novel bioactive peptide products MJ Calcott, DF Ackerley Biotechnology letters 36, 2407-2416, 2014 | 73 | 2014 |
Generating functional recombinant NRPS enzymes in the laboratory setting via peptidyl carrier protein engineering JG Owen, MJ Calcott, KJ Robins, DF Ackerley Cell chemical biology 23 (11), 1395-1406, 2016 | 44 | 2016 |
High-throughput screening for inhibitors of the SARS-CoV-2 protease using a FRET-biosensor AS Brown, DF Ackerley, MJ Calcott Molecules 25 (20), 4666, 2020 | 32 | 2020 |
Portability of the thiolation domain in recombinant pyoverdine non-ribosomal peptide synthetases MJ Calcott, DF Ackerley BMC microbiology 15, 1-13, 2015 | 32 | 2015 |
Metagenomic domain substitution for the high-throughput modification of nonribosomal peptides SR Messenger, EMR McGuinniety, LJ Stevenson, JG Owen, GL Challis, ... Nature Chemical Biology 20 (2), 251-260, 2024 | 13 | 2024 |
The indigoidine synthetase BpsA provides a colorimetric ATP assay that can be adapted to quantify the substrate preferences of other NRPS enzymes AS Brown, MJ Calcott, VM Collins, JG Owen, DF Ackerley Biotechnology Letters 42, 2665-2671, 2020 | 11 | 2020 |
Intracellular complexities of acquiring a new enzymatic function revealed by mass-randomisation of active-site residues KR Hall, KJ Robins, EM Williams, MH Rich, MJ Calcott, JN Copp, RF Little, ... Elife 9, e59081, 2020 | 9* | 2020 |
Cyclotheonellazoles D-I, Potent Elastase Inhibitory Thiazole-Containing Cyclic Peptides from Theonella sp. (2131) DC Holland, WA Schroder, MJ Calcott, E Kaemmerer, VM Avery, ... Journal of Natural Products 86 (9), 2216-2227, 2023 | 4 | 2023 |
A genomic survey of the natural product biosynthetic potential of actinomycetes isolated from New Zealand lichens P Hou, VV Nowak, CJ Taylor, MJ Calcott, A Knight, JG Owen Msystems 8 (2), e01030-22, 2023 | 3 | 2023 |
Heterologous Expression of Epoxomicin in Escherichia coli SR Messenger, DF Ackerley, MJ Calcott ACS Synthetic Biology 13 (9), 2702-2709, 2024 | 1 | 2024 |
Cheminformatics-Guided Exploration of Synthetic Marine Natural Product-Inspired Brominated Indole-3-Glyoxylamides and Their Potentials for Drug Discovery DC Holland, DW Prebble, MJ Calcott, WA Schroder, F Ferretti, A Lock, ... Molecules 29 (15), 3648, 2024 | | 2024 |
Non-ribosomal peptides and synthetases and methods of preparation and use thereof D Ackerley, M Calcott US Patent App. 17/642,492, 2022 | | 2022 |