Inflammation alters the expression of DMT 1, FPN 1 and hepcidin, and it causes iron accumulation in central nervous system cells P Urrutia, P Aguirre, A Esparza, V Tapia, NP Mena, M Arredondo, ... Journal of neurochemistry 126 (4), 541-549, 2013 | 362 | 2013 |
The interplay between iron accumulation, mitochondrial dysfunction, and inflammation during the execution step of neurodegenerative disorders PJ Urrutia, NP Mena, MT Núñez Frontiers in pharmacology 5, 38, 2014 | 260 | 2014 |
Iron toxicity in neurodegeneration MT Núñez, P Urrutia, N Mena, P Aguirre, V Tapia, J Salazar Biometals 25, 761-776, 2012 | 224 | 2012 |
Mitochondrial iron homeostasis and its dysfunctions in neurodegenerative disorders NP Mena, PJ Urrutia, F Lourido, CM Carrasco, MT Núñez Mitochondrion 21, 92-105, 2015 | 166 | 2015 |
Dissecting the role of redox signaling in neuronal development DA Bórquez, PJ Urrutia, C Wilson, B Van Zundert, MT Núñez, ... Journal of neurochemistry 137 (4), 506-517, 2016 | 93 | 2016 |
The dopamine metabolite aminochrome inhibits mitochondrial complex I and modifies the expression of iron transporters DMT1 and FPN1 P Aguirre, P Urrutia, V Tapia, M Villa, I Paris, J Segura-Aguilar, MT Núñez Biometals 25, 795-803, 2012 | 86 | 2012 |
Inflaming the brain with iron PJ Urrutia, DA Bórquez, MT Núñez Antioxidants 10 (1), 61, 2021 | 78 | 2021 |
Hepcidin attenuates amyloid beta‐induced inflammatory and pro‐oxidant responses in astrocytes and microglia PJ Urrutia, EC Hirsch, C González‐Billault, MT Núñez Journal of Neurochemistry 142 (1), 140-152, 2017 | 62 | 2017 |
Cdk5 regulation of the GRAB-mediated Rab8-Rab11 cascade in axon outgrowth K Furusawa, A Asada, P Urrutia, C Gonzalez-Billault, M Fukuda, ... Journal of Neuroscience 37 (4), 790-806, 2017 | 52 | 2017 |
The novel mitochondrial iron chelator 5-((methylamino) methyl)-8-hydroxyquinoline protects against mitochondrial-induced oxidative damage and neuronal death NP Mena, O García-Beltrán, F Lourido, PJ Urrutia, R Mena, ... Biochemical and Biophysical Research Communications 463 (4), 787-792, 2015 | 49 | 2015 |
Cell death induced by mitochondrial complex I inhibition is mediated by Iron Regulatory Protein 1 PJ Urrutia, P Aguirre, V Tapia, CM Carrasco, NP Mena, MT Núñez Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (9 …, 2017 | 33 | 2017 |
On the chemical and biological characteristics of multifunctional compounds for the treatment of Parkinson’s disease O García-Beltrán, PJ Urrutia, MT Núñez Antioxidants 12 (2), 214, 2023 | 14 | 2023 |
Iron, the endolysosomal system and neuroinflammation: a matter of balance DA Bórquez, PJ Urrutia, MT Núñez Neural Regeneration Research 17 (5), 1003-1004, 2022 | 10 | 2022 |
Tuba activates Cdc42 during neuronal polarization downstream of the small GTPase Rab8a PJ Urrutia, F Bodaleo, DA Bórquez, Y Homma, V Rozes-Salvador, ... Journal of Neuroscience 41 (8), 1636-1649, 2021 | 8 | 2021 |
Expanded bioinformatic analysis of Oximouse dataset reveals key putative processes involved in brain aging and cognitive decline PJ Urrutia, DA Bórquez Free Radical Biology and Medicine 207, 200-211, 2023 | 2 | 2023 |
A role for second messengers in axodendritic neuronal polarity PJ Urrutia, C González-Billault Journal of Neuroscience 43 (12), 2037-2052, 2023 | 2 | 2023 |
New players in neuronal Iron homeostasis: insights from CRISPRi studies DA Bórquez, F Castro, MT Núñez, PJ Urrutia Antioxidants 11 (9), 1807, 2022 | 2 | 2022 |
Iron Neurotoxicity in Parkinson’s Disease MT Nunez, P Urrutia, N Mena, P Aguirre In Handbook of Neurotoxicity, 789-818, 2014 | 2 | 2014 |
Iron Neurotoxicity in Parkinson’s Disease PJ Urrutia, D Bórquez, MT Núñez Handbook of Neurotoxicity, 2219-2241, 2023 | 1 | 2023 |
Iron toxicity in neurodegeneration M Núñez González, PJ Urrutia, N Mena, P Aguirre, V Tapia, J Salazar | 1 | 2012 |