Running in reverse: the structural basis for translocation polarity in hexameric helicases ND Thomsen, JM Berger Cell 139 (3), 523-534, 2009 | 332 | 2009 |
A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP6 in mRNA export B Montpetit, ND Thomsen, KJ Helmke, MA Seeliger, JM Berger, K Weis Nature 472 (7342), 238-242, 2011 | 267 | 2011 |
The structural basis for substrate specificity in DNA topoisomerase IV KD Corbett, AJ Schoeffler, ND Thomsen, JM Berger Journal of molecular biology 351 (3), 545-561, 2005 | 194 | 2005 |
A small-molecule mimic of a peptide docking motif inhibits the protein kinase PDK1 TJ Rettenmaier, JD Sadowsky, ND Thomsen, SC Chen, AK Doak, ... Proceedings of the National Academy of Sciences 111 (52), 18590-18595, 2014 | 91 | 2014 |
Cacidases: caspases can cleave after aspartate, glutamate and phosphoserine residues JE Seaman, O Julien, PS Lee, TJ Rettenmaier, ND Thomsen, JA Wells Cell Death & Differentiation 23 (10), 1717-1726, 2016 | 86 | 2016 |
Nature-inspired design of motif-specific antibody scaffolds JT Koerber, ND Thomsen, BT Hannigan, WF Degrado, JA Wells Nature biotechnology 31 (10), 916-921, 2013 | 83 | 2013 |
Structural snapshots reveal distinct mechanisms of procaspase-3 and-7 activation ND Thomsen, JT Koerber, JA Wells Proceedings of the National Academy of Sciences 110 (21), 8477-8482, 2013 | 71 | 2013 |
Structural frameworks for considering microbial protein‐and nucleic acid‐dependent motor ATPases ND Thomsen, JM Berger Molecular microbiology 69 (5), 1071-1090, 2008 | 65 | 2008 |
Allosteric activation mechanism of the Mycobacterium tuberculosis receptor Ser/Thr protein kinase, PknB TN Lombana, N Echols, MC Good, ND Thomsen, HL Ng, AE Greenstein, ... Structure 18 (12), 1667-1677, 2010 | 64 | 2010 |
Engineering a light-activated caspase-3 for precise ablation of neurons in vivo AD Smart, RA Pache, ND Thomsen, T Kortemme, GW Davis, JA Wells Proceedings of the National Academy of Sciences 114 (39), E8174-E8183, 2017 | 62 | 2017 |
Molecular mechanisms of substrate-controlled ring dynamics and substepping in a nucleic acid-dependent hexameric motor ND Thomsen, MR Lawson, LB Witkowsky, S Qu, JM Berger Proceedings of the National Academy of Sciences 113 (48), E7691-E7700, 2016 | 49 | 2016 |
HIV envelope antibodies and TLR7 agonist partially prevent viral rebound in chronically SHIV-infected monkeys B Moldt, A Chandrashekar, EN Borducchi, JP Nkolola, H Stephenson, ... PLoS pathogens 18 (4), e1010467, 2022 | 17 | 2022 |
Evaluation of broadly neutralizing antibody sensitivity by genotyping and phenotyping for qualifying participants to HIV clinical trials B Moldt, A Parvangada, R Martin, C Pace, M Balakrishnan, ND Thomsen, ... JAIDS Journal of Acquired Immune Deficiency Syndromes 88 (1), 61-69, 2021 | 8 | 2021 |
Crystallization and X-ray structure determination of an RNA-dependent hexameric helicase ND Thomsen, JM Berger Methods in enzymology 511, 171-190, 2012 | 7 | 2012 |
Human immunodeficiency virus neutralizing antibodies M Balakrishnan, BA Carr, J Corbin, CS Pace, ND Thomsen, X Zhang US Patent 10,882,898, 2021 | 3 | 2021 |
Multispecific antibodies that target HIV GP120 and CD3 D Rehder, MR Schenauer, H Stephenson, ND Thomsen US Patent 10,882,907, 2021 | 3 | 2021 |
GS-9722: first-in-class effector-enhanced broadly neutralizing antibody for HIV cure N Thomsen, M Balakrishnana, CS Pace Poster 356, 4-7, 0 | 3 | |
Antibodies that target HIV GP120 and methods of use M Balakrishnan, BA Carr, CS Pace, D Rehder, MR Schenauer, L Serafini, ... US Patent 11,168,130, 2021 | 2 | 2021 |
Multi-specific antigen binding molecules targeting hiv and methods of use M Baca, WS Blair, BA Carr, SB Clancy, J Goldsmith, MS Hung, M Kanwar, ... US Patent App. 17/409,260, 2023 | 1 | 2023 |
Antibodies that target hiv gp120 and methods of use M Balakrishnan, BA Carr, MS Hung, M Kanwar, CS Pace, D Rehder, ... US Patent App. 17/496,250, 2022 | 1 | 2022 |