关注
NATHAN D THOMSEN
NATHAN D THOMSEN
Damon Runyon Fellow, UCSF
在 ucsf.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Running in reverse: the structural basis for translocation polarity in hexameric helicases
ND Thomsen, JM Berger
Cell 139 (3), 523-534, 2009
3322009
A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP6 in mRNA export
B Montpetit, ND Thomsen, KJ Helmke, MA Seeliger, JM Berger, K Weis
Nature 472 (7342), 238-242, 2011
2672011
The structural basis for substrate specificity in DNA topoisomerase IV
KD Corbett, AJ Schoeffler, ND Thomsen, JM Berger
Journal of molecular biology 351 (3), 545-561, 2005
1942005
A small-molecule mimic of a peptide docking motif inhibits the protein kinase PDK1
TJ Rettenmaier, JD Sadowsky, ND Thomsen, SC Chen, AK Doak, ...
Proceedings of the National Academy of Sciences 111 (52), 18590-18595, 2014
912014
Cacidases: caspases can cleave after aspartate, glutamate and phosphoserine residues
JE Seaman, O Julien, PS Lee, TJ Rettenmaier, ND Thomsen, JA Wells
Cell Death & Differentiation 23 (10), 1717-1726, 2016
862016
Nature-inspired design of motif-specific antibody scaffolds
JT Koerber, ND Thomsen, BT Hannigan, WF Degrado, JA Wells
Nature biotechnology 31 (10), 916-921, 2013
832013
Structural snapshots reveal distinct mechanisms of procaspase-3 and-7 activation
ND Thomsen, JT Koerber, JA Wells
Proceedings of the National Academy of Sciences 110 (21), 8477-8482, 2013
712013
Structural frameworks for considering microbial protein‐and nucleic acid‐dependent motor ATPases
ND Thomsen, JM Berger
Molecular microbiology 69 (5), 1071-1090, 2008
652008
Allosteric activation mechanism of the Mycobacterium tuberculosis receptor Ser/Thr protein kinase, PknB
TN Lombana, N Echols, MC Good, ND Thomsen, HL Ng, AE Greenstein, ...
Structure 18 (12), 1667-1677, 2010
642010
Engineering a light-activated caspase-3 for precise ablation of neurons in vivo
AD Smart, RA Pache, ND Thomsen, T Kortemme, GW Davis, JA Wells
Proceedings of the National Academy of Sciences 114 (39), E8174-E8183, 2017
622017
Molecular mechanisms of substrate-controlled ring dynamics and substepping in a nucleic acid-dependent hexameric motor
ND Thomsen, MR Lawson, LB Witkowsky, S Qu, JM Berger
Proceedings of the National Academy of Sciences 113 (48), E7691-E7700, 2016
492016
HIV envelope antibodies and TLR7 agonist partially prevent viral rebound in chronically SHIV-infected monkeys
B Moldt, A Chandrashekar, EN Borducchi, JP Nkolola, H Stephenson, ...
PLoS pathogens 18 (4), e1010467, 2022
172022
Evaluation of broadly neutralizing antibody sensitivity by genotyping and phenotyping for qualifying participants to HIV clinical trials
B Moldt, A Parvangada, R Martin, C Pace, M Balakrishnan, ND Thomsen, ...
JAIDS Journal of Acquired Immune Deficiency Syndromes 88 (1), 61-69, 2021
82021
Crystallization and X-ray structure determination of an RNA-dependent hexameric helicase
ND Thomsen, JM Berger
Methods in enzymology 511, 171-190, 2012
72012
Human immunodeficiency virus neutralizing antibodies
M Balakrishnan, BA Carr, J Corbin, CS Pace, ND Thomsen, X Zhang
US Patent 10,882,898, 2021
32021
Multispecific antibodies that target HIV GP120 and CD3
D Rehder, MR Schenauer, H Stephenson, ND Thomsen
US Patent 10,882,907, 2021
32021
GS-9722: first-in-class effector-enhanced broadly neutralizing antibody for HIV cure
N Thomsen, M Balakrishnana, CS Pace
Poster 356, 4-7, 0
3
Antibodies that target HIV GP120 and methods of use
M Balakrishnan, BA Carr, CS Pace, D Rehder, MR Schenauer, L Serafini, ...
US Patent 11,168,130, 2021
22021
Multi-specific antigen binding molecules targeting hiv and methods of use
M Baca, WS Blair, BA Carr, SB Clancy, J Goldsmith, MS Hung, M Kanwar, ...
US Patent App. 17/409,260, 2023
12023
Antibodies that target hiv gp120 and methods of use
M Balakrishnan, BA Carr, MS Hung, M Kanwar, CS Pace, D Rehder, ...
US Patent App. 17/496,250, 2022
12022
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