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Aniruddha Karve
Aniruddha Karve
Senior Scientist, AstraZeneca
在 astrazeneca.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Phosphoinositide 3-Kinase (PI3K) reactive oxygen species (ROS)-activated prodrug in combination with anthracycline impairs pi3k signaling, increases DNA damage response and …
R Mishra, L Yuan, H Patel, AS Karve, H Zhu, A White, S Alanazi, P Desai, ...
International Journal of Molecular Sciences 22 (4), 2088, 2021
202021
mTOR kinase inhibition reduces tissue factor expression and growth of pancreatic neuroendocrine tumors
CS Lewis, HE Thomas, MA Orr‐Asman, LC Green, RE Boody, K Matiash, ...
Journal of thrombosis and haemostasis 17 (1), 169-182, 2019
152019
A review of approaches to potentiate the activity of temozolomide against glioblastoma to overcome resistance
AS Karve, JM Desai, SN Gadgil, N Dave, TM Wise-Draper, GA Gudelsky, ...
International Journal of Molecular Sciences 25 (6), 3217, 2024
112024
Potentiation of temozolomide activity against glioblastoma cells by aromatase inhibitor letrozole
AS Karve, JM Desai, N Dave, TM Wise-Draper, GA Gudelsky, TN Phoenix, ...
Cancer chemotherapy and pharmacology 90 (4), 345-356, 2022
82022
Brain pharmacokinetics and metabolism of the AMP-activated protein kinase selective inhibitor SBI-0206965, an investigational agent for the treatment of glioblastoma
JM Desai, AS Karve, GA Gudelsky, MV Gawali, W Seibel, L Sallans, ...
Investigational new drugs 40 (5), 944-952, 2022
72022
A first-in-class, humanized antibody targeting alternatively spliced tissue factor: preclinical evaluation in an orthotopic model of pancreatic ductal adenocarcinoma
CS Lewis, A Karve, K Matiash, T Stone, J Li, JK Wang, HH Versteeg, ...
Frontiers in Oncology 11, 691685, 2021
72021
Reuse of molecules for glioblastoma therapy
A Koehler, A Karve, P Desai, J Arbiser, DR Plas, X Qi, RD Read, ...
Pharmaceuticals 14 (2), 99, 2021
52021
Pharmacokinetics of levetiracetam seizure prophylaxis in severe traumatic brain injury
SS Harlan, CD Philpott, SP Keegan, ME Droege, AS Karve, B Foreman, ...
Annals of Pharmacotherapy 58 (7), 705-714, 2024
22024
A Phase 0/I Pharmacokinetic and Pharmacodynamics and Safety and Tolerability Study of Letrozole in Combination with Standard Therapy in Recurrent High-Grade Gliomas
PB Desai, AS Karve, M Zawit, P Arora, N Dave, J Awosika, N Li, ...
Clinical Cancer Research 30 (10), 2068-2077, 2024
22024
GABA (A) Receptor Activation Drives GABARAP–Nix Mediated Autophagy to Radiation-Sensitize Primary and Brain-Metastatic Lung Adenocarcinoma Tumors
D Bhattacharya, R Barrile, DK Toukam, VS Gawali, L Kallay, T Ahmed, ...
Cancers 16 (18), 3167, 2024
12024
Bzd-1 as a chemosensitizer of cancer
DP Krummel, S Sengupta, JM Cook, T Ahmed, A Karve, L Kallay, P Desai, ...
US Patent App. 18/564,894, 2024
2024
GABA (A) receptor activation drives GABARAP-Nix mediated autophagy to radiosensitize primary and metastatic lung adenocarcinoma tumors
D Bhattacharya, R Barrile, DK Toukam, VS Gawali, L Kallay, T Ahmed, ...
Cancer Research 84 (6_Supplement), 703-703, 2024
2024
Translational research to facilitate development of novel therapeutic combinations of letrozole for the treatment of glioblastoma
AS Karve, BB Gabani, SN Gadgil, SP Kulkarni, GA Gudelsky, PB Desai
Cancer Research 84 (6_Supplement), 2119-2119, 2024
2024
1286: IMPACT OF AUGMENTED RENAL CLEARANCE ON VANCOMYCIN IN CRITICALLY ILL TRAUMA PATIENTS
T Rice, M Droege, C Philpott, J Courter, P Desai, N Harger, N Ernst, ...
Critical Care Medicine 51 (1), 642, 2023
2023
ACTIVATING AN ION CHANNEL PROMOTES RADIATION-SENSITIZING IMMUNE-DRIVEN ANTI-TUMOR ACTIVITY
DK Toukam, D Bhattacharya, V Gawali, L Kallay, A Karve, P Desai, ...
NEURO-ONCOLOGY 24, 246-247, 2022
2022
EXTH-101. MECHANISTIC INSIGHTS INTO CYTOTOXIC EFFECTS OF LETROZOLE AGAINST GLIOBLASTOMA CELLS
A Karve, J Desai, N Dave, T Phoenix, G Gudelsky, D Plas, B Dasgupta, ...
Neuro-Oncology 24 (Suppl 7), vii233, 2022
2022
EXTH-99. SYSTEMIC AND BRAIN PHARMACOKINETICS OF A GABAA RECEPTOR AGONIST, AMLAL-101, AS AN INVESTIGATIONAL THERAPEUTIC FOR THE …
A Karve, T Ahmed, J Desai, D Bhattacharya, DK Toukam, S Gadgil, ...
Neuro-Oncology 24 (Supplement_7), vii232-vii233, 2022
2022
RBIO-02. ACTIVATION OF GABAA RECEPTORS WITH A NON-TOXIC, BRAIN PENETRANT SMALL MOLECULE SENSITIZES LUNG ADENOCARCINOMA …
D Bhattacharya, R Barille, DK Toukam, V Gawali, L Kallay, T Ahmed, ...
Neuro-Oncology 24 (Supplement_7), vii247-vii247, 2022
2022
Translational Research to Facilitate Development of Novel Therapeutics for the Treatment of Glioblastoma
AS Karve
University of Cincinnati, 2022
2022
EXTH-52. SYSTEMIC AND BRAIN PHARMACOKINETICS OF THE AMP-ACTIVATED PROTEIN KINASE SELECTIVE INHIBITOR SBI-0206965 AS A POTENTIAL THERAPEUTIC AGENT FOR THE TREATMENT OF …
J Desai, M Gawali, A Karve, G Gudelsky, L Sallans, B Dasgupta, W Seibel, ...
Neuro-Oncology 23 (Supplement_6), vi175-vi175, 2021
2021
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