| Exosomes from bone marrow mesenchymal stem cells contain a microRNA that promotes dormancy in metastatic breast cancer cells M Ono, N Kosaka, N Tominaga, Y Yoshioka, F Takeshita, R Takahashi, ... Science signaling 7 (332), ra63-ra63, 2014 | 697 | 2014 |
| Drug resistance driven by cancer stem cells and their niche M Prieto-Vila, R Takahashi, W Usuba, I Kohama, T Ochiya International journal of molecular sciences 18 (12), 2574, 2017 | 531 | 2017 |
| Systemic delivery of synthetic microRNA-16 inhibits the growth of metastatic prostate tumors via downregulation of multiple cell-cycle genes F Takeshita, L Patrawala, M Osaki, R Takahashi, Y Yamamoto, N Kosaka, ... Molecular Therapy 18 (1), 181-187, 2010 | 512 | 2010 |
| miR-22 represses cancer progression by inducing cellular senescence D Xu, F Takeshita, Y Hino, S Fukunaga, Y Kudo, A Tamaki, J Matsunaga, ... Journal of Cell Biology 193 (2), 409-424, 2011 | 356 | 2011 |
| Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches JA Welsh, DCI Goberdhan, L O'Driscoll, EI Buzas, C Blenkiron, ... Journal of extracellular vesicles 13 (2), e12404, 2024 | 322 | 2024 |
| Conversion of terminally committed hepatocytes to culturable bipotent progenitor cells with regenerative capacity T Katsuda, M Kawamata, K Hagiwara, R Takahashi, Y Yamamoto, ... Cell stem cell 20 (1), 41-55, 2017 | 245 | 2017 |
| The role of microRNAs in the regulation of cancer stem cells R Takahashi, H Miyazaki, T Ochiya Frontiers in genetics 4, 295, 2014 | 199 | 2014 |
| The roles of microRNAs in breast cancer R Takahashi, H Miyazaki, T Ochiya Cancers 7 (2), 598-616, 2015 | 173 | 2015 |
| Loss of microRNA-27b contributes to breast cancer stem cell generation by activating ENPP1 R Takahashi, H Miyazaki, F Takeshita, Y Yamamoto, K Minoura, M Ono, ... Nature communications 6 (1), 7318, 2015 | 160 | 2015 |
| Stilbene derivatives promote Ago2-dependent tumour-suppressive microRNA activity K Hagiwara, N Kosaka, Y Yoshioka, R Takahashi, F Takeshita, T Ochiya Scientific reports 2 (1), 314, 2012 | 160 | 2012 |
| miR‐148a plays a pivotal role in the liver by promoting the hepatospecific phenotype and suppressing the invasiveness of transformed cells L Gailhouste, L Gomez‐Santos, K Hagiwara, I Hatada, N Kitagawa, ... Hepatology 58 (3), 1153-1165, 2013 | 149 | 2013 |
| Therapeutic effects of microRNA-582-5p and-3p on the inhibition of bladder cancer progression K Uchino, F Takeshita, R Takahashi, N Kosaka, K Fujiwara, H Naruoka, ... Molecular Therapy 21 (3), 610-619, 2013 | 126 | 2013 |
| Development of mi RNA‐based therapeutic approaches for cancer patients R Takahashi, M Prieto‐Vila, I Kohama, T Ochiya Cancer science 110 (4), 1140-1147, 2019 | 124 | 2019 |
| An integrative genomic analysis revealed the relevance of microRNA and gene expression for drug-resistance in human breast cancer cells Y Yamamoto, Y Yoshioka, K Minoura, R Takahashi, F Takeshita, T Taya, ... Molecular cancer 10, 1-16, 2011 | 115 | 2011 |
| The role of extracellular vesicle microRNAs in cancer biology R Takahashi, M Prieto-Vila, A Hironaka, T Ochiya Clinical Chemistry and Laboratory Medicine (CCLM) 55 (5), 648-656, 2017 | 110 | 2017 |
| Engineering of SV40-based nano-capsules for delivery of heterologous proteins as fusions with the minor capsid proteins VP2/3 T Inoue, M Kawano, R Takahashi, H Tsukamoto, T Enomoto, T Imai, ... Journal of biotechnology 134 (1-2), 181-192, 2008 | 103 | 2008 |
| Cancer extracellular vesicles contribute to stromal heterogeneity by inducing chemokines in cancer-associated fibroblasts Y Naito, Y Yamamoto, N Sakamoto, I Shimomura, A Kogure, M Kumazaki, ... Oncogene 38 (28), 5566-5579, 2019 | 96 | 2019 |
| Clinical relevance and therapeutic significance of microRNA-133a expression profiles and functions in malignant osteosarcoma-initiating cells T Fujiwara, T Katsuda, K Hagiwara, N Kosaka, Y Yoshioka, RU Takahashi, ... Stem cells 32 (4), 959-973, 2014 | 84 | 2014 |
| Establishment and Characterization of an In Vitro Model of Ovarian Cancer Stem-like Cells with an Enhanced Proliferative Capacity T Ishiguro, A Sato, H Ohata, Y Ikarashi, R Takahashi, T Ochiya, M Yoshida, ... Cancer research 76 (1), 150-160, 2016 | 81 | 2016 |
| Genome engineering of mammalian haploid embryonic stem cells using the Cas9/RNA system T Horii, S Morita, M Kimura, R Kobayashi, D Tamura, R Takahashi, ... PeerJ 1, e230, 2013 | 66 | 2013 |
