| Abortive HIV infection mediates CD4 T cell depletion and inflammation in human lymphoid tissue G Doitsh, M Cavrois, KG Lassen, O Zepeda, Z Yang, ML Santiago, ... Cell 143 (5), 789-801, 2010 | 542 | 2010 |
| Advances in inflammatory bowel disease pathogenesis: linking host genetics and the microbiome D Knights, KG Lassen, RJ Xavier Gut 62 (10), 1505-1510, 2013 | 538 | 2013 |
| Resting CD4+ T Cells from Human Immunodeficiency Virus Type 1 (HIV-1)-Infected Individuals Carry Integrated HIV-1 Genomes within Actively Transcribed Host … Y Han, K Lassen, D Monie, AR Sedaghat, S Shimoji, X Liu, TC Pierson, ... Journal of virology 78 (12), 6122-6133, 2004 | 437 | 2004 |
| Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense KG Lassen, P Kuballa, KL Conway, KK Patel, CE Becker, JM Peloquin, ... Proceedings of the National Academy of Sciences 111 (21), 7741-7746, 2014 | 404 | 2014 |
| Isolation and characterization of replication-competent human immunodeficiency virus type 1 from a subset of elite suppressors JN Blankson, JR Bailey, S Thayil, HC Yang, K Lassen, J Lai, SK Gandhi, ... Journal of virology 81 (5), 2508-2518, 2007 | 348 | 2007 |
| Epigenetic silencing of human immunodeficiency virus (HIV) transcription by formation of restrictive chromatin structures at the viral long terminal repeat drives the … R Pearson, YK Kim, J Hokello, K Lassen, J Friedman, M Tyagi, J Karn Journal of virology 82 (24), 12291-12303, 2008 | 333 | 2008 |
| The multifactorial nature of HIV-1 latency K Lassen, Y Han, Y Zhou, J Siliciano, RF Siliciano Trends in molecular medicine 10 (11), 525-531, 2004 | 322 | 2004 |
| Nuclear Retention of Multiply Spliced HIV-1 RNA in Resting CD4+ T Cells KG Lassen, KX Ramyar, JR Bailey, Y Zhou, RF Siliciano PLoS pathogens 2 (7), e68, 2006 | 245 | 2006 |
| Neutralizing antibodies do not mediate suppression of human immunodeficiency virus type 1 in elite suppressors or selection of plasma virus variants in patients on highly … JR Bailey, KG Lassen, HC Yang, TC Quinn, SC Ray, JN Blankson, ... Journal of virology 80 (10), 4758-4770, 2006 | 226 | 2006 |
| Analysis of Human Immunodeficiency Virus Type 1 Transcriptional Elongation in Resting CD4+ T Cells In Vivo KG Lassen, JR Bailey, RF Siliciano Journal of virology 78 (17), 9105-9114, 2004 | 202 | 2004 |
| A flexible model of HIV-1 latency permitting evaluation of many primary CD4 T-cell reservoirs KG Lassen, AM Hebbeler, D Bhattacharyya, MA Lobritz, WC Greene PloS one 7 (1), e30176, 2012 | 154 | 2012 |
| A noncanonical autophagy pathway restricts Toxoplasma gondii growth in a strain-specific manner in IFN-γ-activated human cells EM Selleck, RC Orchard, KG Lassen, WL Beatty, RJ Xavier, B Levine, ... MBio 6 (5), 10.1128/mbio. 01157-15, 2015 | 138 | 2015 |
| Genetic coding variant in GPR65 alters lysosomal pH and links lysosomal dysfunction with colitis risk KG Lassen, CI McKenzie, M Mari, T Murano, J Begun, LA Baxt, G Goel, ... Immunity 44 (6), 1392-1405, 2016 | 123 | 2016 |
| Activation of HIV transcription by the viral Tat protein requires a demethylation step mediated by lysine-specific demethylase 1 (LSD1/KDM1) N Sakane, HS Kwon, S Pagans, K Kaehlcke, Y Mizusawa, M Kamada, ... PLoS pathogens 7 (8), e1002184, 2011 | 121 | 2011 |
| Elite suppressor–derived HIV-1 envelope glycoproteins exhibit reduced entry efficiency and kinetics KG Lassen, MA Lobritz, JR Bailey, S Johnston, S Nguyen, B Lee, T Chou, ... PLoS pathogens 5 (4), e1000377, 2009 | 121 | 2009 |
| A quantitative affinity-profiling system that reveals distinct CD4/CCR5 usage patterns among human immunodeficiency virus type 1 and simian immunodeficiency virus strains SH Johnston, MA Lobritz, S Nguyen, K Lassen, S Delair, F Posta, ... Journal of virology 83 (21), 11016-11026, 2009 | 117 | 2009 |
| Cross-tissue, single-cell stromal atlas identifies shared pathological fibroblast phenotypes in four chronic inflammatory diseases I Korsunsky, K Wei, M Pohin, EY Kim, F Barone, T Major, E Taylor, ... Med 3 (7), 481-518. e14, 2022 | 114 | 2022 |
| Gasdermin D in macrophages restrains colitis by controlling cGAS-mediated inflammation C Ma, D Yang, B Wang, C Wu, Y Wu, S Li, X Liu, K Lassen, L Dai, S Yang Science advances 6 (21), eaaz6717, 2020 | 114 | 2020 |
| C1orf106 is a colitis risk gene that regulates stability of epithelial adherens junctions V Mohanan, T Nakata, AN Desch, C Lévesque, A Boroughs, G Guzman, ... Science 359 (6380), 1161-1166, 2018 | 112 | 2018 |
| The Crohn’s disease polymorphism, ATG16L1 T300A, alters the gut microbiota and enhances the local Th1/Th17 response S Lavoie, KL Conway, KG Lassen, HB Jijon, H Pan, E Chun, M Michaud, ... Elife 8, e39982, 2019 | 111 | 2019 |
