Development and validation of a simplified method to generate human microglia from pluripotent stem cells A McQuade, M Coburn, CH Tu, J Hasselmann, H Davtyan, ... Molecular neurodegeneration 13, 1-13, 2018 | 337 | 2018 |
Development of a chimeric model to study and manipulate human microglia in vivo J Hasselmann, MA Coburn, W England, DXF Velez, SK Shabestari, ... Neuron 103 (6), 1016-1033. e10, 2019 | 302 | 2019 |
Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer’s disease A McQuade, YJ Kang, J Hasselmann, A Jairaman, A Sotelo, M Coburn, ... Nature communications 11 (1), 5370, 2020 | 258 | 2020 |
Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice SK Shabestari, S Morabito, EP Danhash, A McQuade, JR Sanchez, ... Cell reports 39 (11), 2022 | 90 | 2022 |
Perinatal exposure to concentrated ambient particulates results in autism-like behavioral deficits in adult mice JS Church, PB Tijerina, FJ Emerson, MA Coburn, JL Blum, JT Zelikoff, ... Neurotoxicology 65, 231-240, 2018 | 59 | 2018 |
Behavioral impact of maternal allergic-asthma in two genetically distinct mouse strains JJ Schwartzer, M Careaga, MA Coburn, DR Rose, HK Hughes, ... Brain, behavior, and immunity 63, 99-107, 2017 | 55 | 2017 |
The P522R protective variant of PLCG2 promotes the expression of antigen presentation genes by human microglia in an Alzheimer's disease mouse model C Claes, WE England, EP Danhash, S Kiani Shabestari, A Jairaman, ... Alzheimer's & Dementia 18 (10), 1765-1778, 2022 | 34 | 2022 |
Testing a MultiTEP-based combination vaccine to reduce Aβ and tau pathology in Tau22/5xFAD bigenic mice H Davtyan, A Hovakimyan, S Kiani Shabestari, T Antonyan, MA Coburn, ... Alzheimer's Research & Therapy 11, 1-13, 2019 | 29 | 2019 |
Author Correction: Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer’s disease A McQuade, YJ Kang, J Hasselmann, A Jairaman, A Sotelo, M Coburn, ... nature communications 14, 2023 | 24 | 2023 |
A MultiTEP platform-based epitope vaccine targeting the phosphatase activating domain (PAD) of tau: Therapeutic efficacy in PS19 mice A Hovakimyan, T Antonyan, SK Shabestari, O Svystun, G Chailyan, ... Scientific reports 9 (1), 15455, 2019 | 20 | 2019 |
Microglia promote anti-tumour immunity and suppress breast cancer brain metastasis KT Evans, K Blake, A Longworth, MA Coburn, J Insua-Rodríguez, ... Nature Cell Biology 25 (12), 1848-1859, 2023 | 18 | 2023 |
Distinguishing the effects of systemic CSF1R inhibition by PLX3397 on microglia and peripheral immune cells AK Okojie, JO Uweru, MA Coburn, S Li, VD Cao-Dao, UB Eyo Journal of Neuroinflammation 20 (1), 242, 2023 | 17 | 2023 |
The emergence of the calvarial hematopoietic niche in health and disease WA Mills III, MA Coburn, UB Eyo Immunological reviews 311 (1), 26-38, 2022 | 10 | 2022 |
Using Chimeric Models to Study the Interactions between Human Microglia and Alzheimer’s Disease Pathology in vivo MA Coburn University of California, Irvine, 2021 | | 2021 |
Examining the effects of the microglial PLCG2 P522R mutation by transplantation of human stem cell‐derived microglia in chimeric AD mice: Molecular and cell biology/stem cells … C Claes, E Danhash, J Hasselmann, JP Chadarevian, SK Shabestari, ... Alzheimer's & Dementia 16, e041539, 2020 | | 2020 |