HLA-haploidentical bone marrow transplantation for hematologic malignancies using nonmyeloablative conditioning and high-dose, posttransplantation cyclophosphamide L Luznik, PV O'Donnell, HJ Symons, AR Chen, MS Leffell, M Zahurak, ... Biology of Blood and Marrow Transplantation 14 (6), 641-650, 2008 | 1920 | 2008 |
The complement inhibitor eculizumab in paroxysmal nocturnal hemoglobinuria P Hillmen, NS Young, J Schubert, RA Brodsky, G Socié, P Muus, A Röth, ... New England Journal of Medicine 355 (12), 1233-1243, 2006 | 1440 | 2006 |
Cyclophosphamide and cancer: golden anniversary A Emadi, RJ Jones, RA Brodsky Nature reviews Clinical oncology 6 (11), 638-647, 2009 | 1045 | 2009 |
Discovery and development of the complement inhibitor eculizumab for the treatment of paroxysmal nocturnal hemoglobinuria RP Rother, SA Rollins, CF Mojcik, RA Brodsky, L Bell Nature biotechnology 25 (11), 1256-1264, 2007 | 912 | 2007 |
Effect of the complement inhibitor eculizumab on thromboembolism in patients with paroxysmal nocturnal hemoglobinuria P Hillmen, P Muus, U Dührsen, AM Risitano, J Schubert, L Luzzatto, ... Blood, The Journal of the American Society of Hematology 110 (12), 4123-4128, 2007 | 721 | 2007 |
Multicenter phase 3 study of the complement inhibitor eculizumab for the treatment of patients with paroxysmal nocturnal hemoglobinuria RA Brodsky, NS Young, E Antonioli, AM Risitano, H Schrezenmeier, ... Blood, The Journal of the American Society of Hematology 111 (4), 1840-1847, 2008 | 715 | 2008 |
Paroxysmal nocturnal hemoglobinuria RA Brodsky Hematology: Basic principles and practice 4, 419-27, 2005 | 692* | 2005 |
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Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes P Mali, BK Chou, J Yen, Z Ye, J Zou, S Dowey, RA Brodsky, JE Ohm, ... Stem cells 28 (4), 713-720, 2010 | 566 | 2010 |
Haploinsufficiency of telomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita M Armanios, JL Chen, YPC Chang, RA Brodsky, A Hawkins, CA Griffin, ... Proceedings of the National Academy of Sciences 102 (44), 15960-15964, 2005 | 560 | 2005 |
Effectiveness of exome and genome sequencing guided by acuity of illness for diagnosis of neurodevelopmental disorders SE Soden, CJ Saunders, LK Willig, EG Farrow, LD Smith, JE Petrikin, ... Science translational medicine 6 (265), 265ra168-265ra168, 2014 | 530 | 2014 |
High-dose cyclophosphamide as single-agent, short-course prophylaxis of graft-versus-host disease L Luznik, J Bolaños-Meade, M Zahurak, AR Chen, BD Smith, R Brodsky, ... Blood, The Journal of the American Society of Hematology 115 (16), 3224-3230, 2010 | 464 | 2010 |
HLA-haploidentical bone marrow transplantation with posttransplant cyclophosphamide expands the donor pool for patients with sickle cell disease J Bolaños-Meade, EJ Fuchs, L Luznik, SM Lanzkron, CJ Gamper, ... Blood, The Journal of the American Society of Hematology 120 (22), 4285-4291, 2012 | 448 | 2012 |
Long‐term safety and efficacy of sustained eculizumab treatment in patients with paroxysmal nocturnal haemoglobinuria P Hillmen, P Muus, A Röth, MO Elebute, AM Risitano, H Schrezenmeier, ... British journal of haematology 162 (1), 62-73, 2013 | 439 | 2013 |
Aplastic anaemia RA Brodsky, RJ Jones The Lancet 365 (9471), 1647-1656, 2005 | 438 | 2005 |
Whole-genome sequencing analysis reveals high specificity of CRISPR/Cas9 and TALEN-based genome editing in human iPSCs C Smith, A Gore, W Yan, L Abalde-Atristain, Z Li, C He, Y Wang, ... Cell stem cell 15 (1), 12-13, 2014 | 432 | 2014 |
Paroxysmal nocturnal haemoglobinuria A Hill, AE DeZern, T Kinoshita, RA Brodsky Nature reviews Disease primers 3 (1), 1-14, 2017 | 396 | 2017 |
Direct activation of the alternative complement pathway by SARS-CoV-2 spike proteins is blocked by factor D inhibition J Yu, X Yuan, H Chen, S Chaturvedi, EM Braunstein, RA Brodsky Blood, The Journal of the American Society of Hematology 136 (18), 2080-2089, 2020 | 344 | 2020 |
Natural history of paroxysmal nocturnal haemoglobinuria using modern diagnostic assays VM Moyo, GL Mukhina, ES Garrett, RA Brodsky British journal of haematology 126 (1), 133-138, 2004 | 342 | 2004 |
Improved detection and characterization of paroxysmal nocturnal hemoglobinuria using fluorescent aerolysin RA Brodsky, GL Mukhina, S Li, KL Nelson, PL Chiurazzi, JT Buckley, ... American journal of clinical pathology 114 (3), 459-466, 2000 | 320 | 2000 |