Genomic atlas of the plasma metabolome prioritizes metabolites implicated in human diseases Y Chen, T Lu, U Pettersson-Kymmer, ID Stewart, G Butler-Laporte, ... Nature Genetics 55 (1), 44-53, 2023 | 127 | 2023 |
H3K27M in Gliomas Causes a One-Step Decrease in H3K27 Methylation and Reduced Spreading within the Constraints of H3K36 Methylation AS Harutyunyan*, H Chen*, T Lu, C Horth, H Nikbakht, B Krug, C Russo, ... Cell Reports 33 (7), 108390, 2020 | 57 | 2020 |
Individuals with common diseases but with a low polygenic risk score could be prioritized for rare variant screening T Lu, S Zhou, H Wu, V Forgetta, CMT Greenwood, JB Richards Genetics in Medicine 23 (3), 508-515, 2021 | 48 | 2021 |
Reshuffling of the ancestral core-eudicot genome shaped chromatin topology and epigenetic modification in Panax ZH Wang, XF Wang, T Lu, MR Li, P Jiang, J Zhao, ST Liu, XQ Fu, ... Nature Communications 13 (1), 1902, 2022 | 45 | 2022 |
Improved prediction of fracture risk leveraging a genome-wide polygenic risk score T Lu*, V Forgetta*, J Keller-Baruch, M Nethander, D Bennett, M Forest, ... Genome Medicine 13 (1), 1-15, 2021 | 44 | 2021 |
Polygenic risk for coronary heart disease acts through atherosclerosis in type 2 diabetes T Lu, V Forgetta, OHY Yu, L Mokry, M Gregory, G Thanassoulis, ... Cardiovascular Diabetology 19, 1-10, 2020 | 32 | 2020 |
Proteome-wide Mendelian randomization implicates nephronectin as an actionable mediator of the effect of obesity on COVID-19 severity S Yoshiji, G Butler-Laporte, T Lu, JDS Willett, CY Su, T Nakanishi, ... Nature Metabolism 5 (2), 248-264, 2023 | 31 | 2023 |
Investigating transcriptome-wide sex dimorphism by multi-level analysis of single-cell RNA sequencing data in ten mouse cell types T Lu, JC Mar Biology of sex Differences 11, 1-20, 2020 | 25 | 2020 |
eXclusionarY: 10 years later, where are the sex chromosomes in GWASs? L Sun, Z Wang, T Lu, TA Manolio, AD Paterson The American Journal of Human Genetics 110 (6), 903-912, 2023 | 21 | 2023 |
Transcriptional reprogramming of skeletal muscle stem cells by the niche environment F Lazure*, R Farouni*, K Sahinyan, DM Blackburn, ... Nature Communications 14 (1), 535, 2023 | 21 | 2023 |
A Polygenic Risk Score to Predict Future Adult Short Stature Among Children T Lu, V Forgetta, H Wu, JRB Perry, KK Ong, CMT Greenwood, ... The Journal of Clinical Endocrinology & Metabolism 106 (7), 1918-1928, 2021 | 21 | 2021 |
Circulating Proteins Influencing Psychiatric Disease: A Mendelian Randomization Study T Lu, V Forgetta, CMT Greenwood, S Zhou, JB Richards Biological Psychiatry 93 (1), 82-91, 2023 | 19 | 2023 |
Polygenic risk score as a possible tool for identifying familial monogenic causes of complex diseases T Lu, V Forgetta, JB Richards, CMT Greenwood Genetics in Medicine 24 (7), 1545-1555, 2022 | 17 | 2022 |
Pan-cancer analysis of mRNA stability for decoding tumour post-transcriptional programs G Perron, P Jandaghi, E Moslemi, T Nishimura, M Rajaee, R Alkallas, ... Communications Biology 5, 851, 2022 | 11 | 2022 |
Whole-genome bisulfite sequencing in systemic sclerosis provides novel targets to understand disease pathogenesis T Lu, KO Klein, I Colmegna, M Lora, CMT Greenwood, M Hudson BMC medical genomics 12, 1-12, 2019 | 11 | 2019 |
Rapid Divergence Followed by Adaptation to Contrasting Ecological Niches of Two Closely Related Columbine Species Aquilegia japonica and A. oxysepala MR Li, HY Wang, N Ding, T Lu, YC Huang, HX Xiao, B Liu, LF Li Genome biology and evolution 11 (3), 919-930, 2019 | 11 | 2019 |
Simultaneous SNP selection and adjustment for population structure in high dimensional prediction models SR Bhatnagar, Y Yang, T Lu, E Schurr, JC Loredo-Osti, M Forest, ... PLoS genetics 16 (5), e1008766, 2020 | 10 | 2020 |
A Sparse Additive Model for High-Dimensional Interactions with an Exposure Variable SR Bhatnagar, T Lu, A Lovato, DL Olds, MS Kobor, MJ Meaney, ... Computational Statistics & Data Analysis, 107624, 2022 | 8 | 2022 |
Capturing additional genetic risk from family history for improved polygenic risk prediction T Lu, V Forgetta, JB Richards, CMT Greenwood Communications Biology 5 (1), 595, 2022 | 7 | 2022 |
Causal associations between body fat accumulation and COVID-19 severity: A Mendelian randomization study S Yoshiji, D Tanaka, M Hiroto, T Lu, G Butler-Laporte, T Murakami, ... Frontiers in Endocrinology 13, 899625, 2022 | 6 | 2022 |