Angiogenic sprouting and capillary lumen formation modeled by human umbilical vein endothelial cells (HUVEC) in fibrin gels: the role of fibroblasts and Angiopoietin-1☆ MN Nakatsu, RCA Sainson, JN Aoto, KL Taylor, M Aitkenhead, ... Microvascular research 66 (2), 102-112, 2003 | 539 | 2003 |
A conserved mechanism for steroid receptor translocation to the plasma membrane A Pedram, M Razandi, RCA Sainson, JK Kim, CC Hughes, ER Levin Journal of Biological Chemistry 282 (31), 22278-22288, 2007 | 536 | 2007 |
Diffusion Limits of an in Vitro Thick Prevascularized Tissue CK Griffith, C Miller, RCA Sainson, JW Calvert, NL Jeon, CCW Hughes, ... Tissue engineering 11 (1-2), 257-266, 2005 | 460 | 2005 |
New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes H Sheldon, E Heikamp, H Turley, R Dragovic, P Thomas, CE Oon, R Leek, ... Blood, The Journal of the American Society of Hematology 116 (13), 2385-2394, 2010 | 454 | 2010 |
Delta-like 4 Notch ligand regulates tumor angiogenesis, improves tumor vascular function, and promotes tumor growth in vivo JL Li, RCA Sainson, W Shi, R Leek, LS Harrington, M Preusser, S Biswas, ... Cancer research 67 (23), 11244-11253, 2007 | 403 | 2007 |
TNF primes endothelial cells for angiogenic sprouting by inducing a tip cell phenotype RCA Sainson, DA Johnston, HC Chu, MT Holderfield, MN Nakatsu, ... Blood, The Journal of the American Society of Hematology 111 (10), 4997-5007, 2008 | 379 | 2008 |
Rational selection of syngeneic preclinical tumor models for immunotherapeutic drug discovery SIS Mosely, JE Prime, RCA Sainson, JO Koopmann, DYQ Wang, ... Cancer immunology research 5 (1), 29-41, 2017 | 375 | 2017 |
Regulation of multiple angiogenic pathways by Dll4 and Notch in human umbilical vein endothelial cells LS Harrington, RCA Sainson, CK Williams, JM Taylor, W Shi, JL Li, ... Microvascular research 75 (2), 144-154, 2008 | 318 | 2008 |
Cell‐autonomous notch signaling regulates endothelial cell branching and proliferation during vascular tubulogenesis RCA Sainson, J Aoto, MN Nakatsu, M Holderfield, E Conn, E Koller, ... The FASEB journal 19 (8), 1027-1029, 2005 | 289 | 2005 |
Regulation of the anti-tumour immune response by cancer-associated fibroblasts J Harper, RCA Sainson Seminars in cancer biology 25, 69-77, 2014 | 277 | 2014 |
DLL4-Notch Signaling Mediates Tumor Resistance to Anti-VEGF Therapy In Vivo JL Li, RCA Sainson, CE Oon, H Turley, R Leek, H Sheldon, E Bridges, ... Cancer research 71 (18), 6073-6083, 2011 | 258 | 2011 |
VEGF121 and VEGF165 regulate blood vessel diameter through vascular endothelial growth factor receptor 2 in an in vitro angiogenesis model MN Nakatsu, RCA Sainson, S Pérez-del-Pulgar, JN Aoto, M Aitkenhead, ... Laboratory investigation 83 (12), 1873-1885, 2003 | 187 | 2003 |
The C-terminal domain of the regulatory protein NOVH is sufficient to promote interaction with fibulin 1C: a clue for a role of NOVH in cell-adhesion signaling B Perbal, C Martinerie, R Sainson, M Werner, B He, B Roizman Proceedings of the National Academy of Sciences 96 (3), 869-874, 1999 | 160 | 1999 |
Active involvement of Robo1 and Robo4 in filopodia formation and endothelial cell motility mediated via WASP and other actin nucleation-promoting factors H Sheldon, M Andre, JA Legg, P Heal, JM Herbert, R Sainson, ... The FASEB Journal 23 (2), 513, 2009 | 142 | 2009 |
MHC class I chain-related protein A and B (MICA and MICB) are predominantly expressed intracellularly in tumour and normal tissue H Ghadially, L Brown, C Lloyd, L Lewis, A Lewis, J Dillon, R Sainson, ... British journal of cancer 116 (9), 1208-1217, 2017 | 119 | 2017 |
Regulation of angiogenesis by homotypic and heterotypic notch signalling in endothelial cells and pericytes: from basic research to potential therapies RCA Sainson, AL Harris Angiogenesis 11, 41-51, 2008 | 117 | 2008 |
Anti-Dll4 therapy: can we block tumour growth by increasing angiogenesis? RCA Sainson, AL Harris Trends in molecular medicine 13 (9), 389-395, 2007 | 117 | 2007 |
Hypoxia-regulated differentiation: let's step it up a Notch RCA Sainson, AL Harris Trends in molecular medicine 12 (4), 141-143, 2006 | 90 | 2006 |
Regulation of CXCR4 by the Notch ligand delta-like 4 in endothelial cells CK Williams, M Segarra, M De La Luz Sierra, RCA Sainson, G Tosato, ... Cancer research 68 (6), 1889-1895, 2008 | 76 | 2008 |
Tumors: wounds that do not heal—a historical perspective with a focus on the fundamental roles of increased vascular permeability and clotting HF Dvorak Seminars in thrombosis and hemostasis 45 (06), 576-592, 2019 | 59 | 2019 |