Silencing of CD47 and SIRPα by Polypurine reverse Hoogsteen hairpins to promote MCF-7 breast cancer cells death by PMA-differentiated THP-1 cells G Bener, A J. Félix, C Sánchez de Diego, I Pascual Fabregat, CJ Ciudad, ... BMC immunology 17, 1-12, 2016 | 35 | 2016 |
Polypurine reverse Hoogsteen hairpins as a gene silencing tool for cancer L Rodriguez, X Villalobos, A J Felix, V Noe Current Medicinal Chemistry 24 (26), 2809-2826, 2017 | 22 | 2017 |
Nucleic acids therapeutics using PolyPurine Reverse Hoogsteen hairpins V Noe, E Aubets, AJ Felix, CJ Ciudad Biochemical Pharmacology 189, 114371, 2021 | 21 | 2021 |
Cancer immunotherapy using PolyPurine Reverse Hoogsteen hairpins targeting the PD-1/PD-L1 pathway in human tumor cells MMM Enriquez, AJ Felix, CJ Ciudad, V Noé PLoS One 13 (11), 2018 | 20 | 2018 |
Functional pharmacogenomics and toxicity of PolyPurine Reverse Hoogsteen hairpins directed against survivin in human cells AJ Félix, CJ Ciudad, V Noé Biochemical Pharmacology 155, 8-20, 2018 | 19 | 2018 |
Correction of the aprt gene using repair-polypurine reverse hoogsteen hairpins in mammalian cells AJ Félix, V Noé Molecular Therapy-Nucleic Acids 19, 683-695, 2020 | 18 | 2020 |
Mapping PTBP2 binding in human brain identifies SYNGAP1 as a target for therapeutic splice switching JM Dawicki-McKenna, AJ Felix, EA Waxman, C Cheng, DA Amado, ... Nature Communications 14 (1), 2628, 2023 | 17 | 2023 |
Synthesis and validation of DOPY: A new gemini dioleylbispyridinium based amphiphile for nucleic acid transfection E Aubets, R Griera, AJ Felix, G Rigol, C Sikorski, D Limon, C Mastrorosa, ... European Journal of Pharmaceutics and Biopharmaceutics 165, 279-292, 2021 | 10 | 2021 |
Gene correction of point mutations using polypurine reverse Hoogsteen hairpins technology AJ Félix, A Solé, V Noé, CJ Ciudad Frontiers in Genome Editing 2, 583577, 2020 | 10 | 2020 |
Detection of a G-Quadruplex as a Regulatory Element in Thymidylate synthase for Gene Silencing Using Polypurine Reverse Hoogsteen Hairpins E Aubets, A J. Félix, M Garavís, L Reyes, A Aviñó, R Eritja, CJ Ciudad, ... International Journal of Molecular Sciences 21 (14), 5028, 2020 | 10 | 2020 |
Detection of SARS-CoV-2 virus by triplex enhanced nucleic acid detection assay (TENADA) A Aviñó, C Cuestas-Ayllón, M Gutiérrez-Capitán, L Vilaplana, V Grazu, ... International journal of molecular sciences 23 (23), 15258, 2022 | 9 | 2022 |
Silencing PD-1 and PD-L1: the potential of PolyPurine Reverse Hoogsteen hairpins for the elimination of tumor cells CJ Ciudad, MM Medina Enriquez, AJ Félix, G Bener, V Noe Immunotherapy 11 (5), 369-372, 2019 | 9 | 2019 |
A novel DNA-binding motif in prostate tumor overexpressed-1 (PTOV1) required for the expression of ALDH1A1 and CCNG2 in cancer cells V Maggio, V Canovas, AJ Felix, V Gomez, I de Torres, ME Semidey, ... Cancer Letters 452, 158-167, 2019 | 6 | 2019 |
Generation of humanized mouse models to support therapeutic development for SYNGAP1 and STXBP1 disorders AJ Felix, T Wilson, R Randell, N Marotta, K Uchida, MJ Boland, ... bioRxiv, 2024 | | 2024 |