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Alex J. Felix
Alex J. Felix
Postdoctoral Fellow, University of Pennsylvania
在 upenn.edu 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Silencing of CD47 and SIRPα by Polypurine reverse Hoogsteen hairpins to promote MCF-7 breast cancer cells death by PMA-differentiated THP-1 cells
G Bener, A J. Félix, C Sánchez de Diego, I Pascual Fabregat, CJ Ciudad, ...
BMC immunology 17, 1-12, 2016
352016
Polypurine reverse Hoogsteen hairpins as a gene silencing tool for cancer
L Rodriguez, X Villalobos, A J Felix, V Noe
Current Medicinal Chemistry 24 (26), 2809-2826, 2017
222017
Nucleic acids therapeutics using PolyPurine Reverse Hoogsteen hairpins
V Noe, E Aubets, AJ Felix, CJ Ciudad
Biochemical Pharmacology 189, 114371, 2021
212021
Cancer immunotherapy using PolyPurine Reverse Hoogsteen hairpins targeting the PD-1/PD-L1 pathway in human tumor cells
MMM Enriquez, AJ Felix, CJ Ciudad, V Noé
PLoS One 13 (11), 2018
202018
Functional pharmacogenomics and toxicity of PolyPurine Reverse Hoogsteen hairpins directed against survivin in human cells
AJ Félix, CJ Ciudad, V Noé
Biochemical Pharmacology 155, 8-20, 2018
192018
Correction of the aprt gene using repair-polypurine reverse hoogsteen hairpins in mammalian cells
AJ Félix, V Noé
Molecular Therapy-Nucleic Acids 19, 683-695, 2020
182020
Mapping PTBP2 binding in human brain identifies SYNGAP1 as a target for therapeutic splice switching
JM Dawicki-McKenna, AJ Felix, EA Waxman, C Cheng, DA Amado, ...
Nature Communications 14 (1), 2628, 2023
172023
Synthesis and validation of DOPY: A new gemini dioleylbispyridinium based amphiphile for nucleic acid transfection
E Aubets, R Griera, AJ Felix, G Rigol, C Sikorski, D Limon, C Mastrorosa, ...
European Journal of Pharmaceutics and Biopharmaceutics 165, 279-292, 2021
102021
Gene correction of point mutations using polypurine reverse Hoogsteen hairpins technology
AJ Félix, A Solé, V Noé, CJ Ciudad
Frontiers in Genome Editing 2, 583577, 2020
102020
Detection of a G-Quadruplex as a Regulatory Element in Thymidylate synthase for Gene Silencing Using Polypurine Reverse Hoogsteen Hairpins
E Aubets, A J. Félix, M Garavís, L Reyes, A Aviñó, R Eritja, CJ Ciudad, ...
International Journal of Molecular Sciences 21 (14), 5028, 2020
102020
Detection of SARS-CoV-2 virus by triplex enhanced nucleic acid detection assay (TENADA)
A Aviñó, C Cuestas-Ayllón, M Gutiérrez-Capitán, L Vilaplana, V Grazu, ...
International journal of molecular sciences 23 (23), 15258, 2022
92022
Silencing PD-1 and PD-L1: the potential of PolyPurine Reverse Hoogsteen hairpins for the elimination of tumor cells
CJ Ciudad, MM Medina Enriquez, AJ Félix, G Bener, V Noe
Immunotherapy 11 (5), 369-372, 2019
92019
A novel DNA-binding motif in prostate tumor overexpressed-1 (PTOV1) required for the expression of ALDH1A1 and CCNG2 in cancer cells
V Maggio, V Canovas, AJ Felix, V Gomez, I de Torres, ME Semidey, ...
Cancer Letters 452, 158-167, 2019
62019
Generation of humanized mouse models to support therapeutic development for SYNGAP1 and STXBP1 disorders
AJ Felix, T Wilson, R Randell, N Marotta, K Uchida, MJ Boland, ...
bioRxiv, 2024
2024
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