| An integrated stress response via PKR suppresses HER2+ cancers and improves trastuzumab therapy C Darini, N Ghaddar, C Chabot, G Assaker, S Sabri, S Wang, ... Nature communications 10 (1), 2139, 2019 | 58 | 2019 |
| The integrated stress response is tumorigenic and constitutes a therapeutic liability in KRAS-driven lung cancer N Ghaddar, S Wang, B Woodvine, J Krishnamoorthy, V van Hoef, C Darini, ... Nature Communications 12 (1), 4651, 2021 | 35 | 2021 |
| Downregulation of PERK activity and eIF2α serine 51 phosphorylation by mTOR complex 1 elicits pro-oxidant and pro-death effects in tuberous sclerosis-deficient cells J Krishnamoorthy, C Tenkerian, J Gupta, N Ghaddar, S Wang, C Darini, ... Cell Death & Disease 9 (3), 254, 2018 | 13 | 2018 |
| Access to high-impact mutations constrains the evolution of antibiotic resistance in soft agar N Ghaddar, M Hashemidahaj, BL Findlay Scientific Reports 8 (1), 17023, 2018 | 10 | 2018 |
| Detection of lung tumor progression in mice by ultrasound imaging N Ghaddar, S Wang, V Michaud, U Kazimierczak, N Ah-Son, ... JoVE (Journal of Visualized Experiments), e60565, 2020 | 6 | 2020 |
| The integrated stress response exposes a therapeutic vulnerability in KRAS driven lung cancer N Ghaddar, S Wang, B Woodvine, J Krishnamoorthy, C Darini, ... European Journal of Cancer 138, S23, 2020 | 1 | 2020 |
| Abstract A022: Translation initiation factor 2B (eIF2B) stimulates mutant KRAS function in cancer H Kim, N Ghaddar, LE Ghahnavieh, S Wang, KJ Cho, A Sasaki, ... Molecular Cancer Research 21 (5_Supplement), A022-A022, 2023 | | 2023 |
| Abstract A017: Deciphering the role of integrated stress response (ISR) in the developmental stages of mutant KRAS lung cancer S Diao, N Ghaddar, JY Zou, S Wang, AE Koromilas Molecular Cancer Research 21 (5_Supplement), A017-A017, 2023 | | 2023 |
| The integrated stress response (ISR) is a focal point of tumorigenic pathways in KRAS lung cancer N Ghaddar McGill University, 2023 | | 2023 |
| The Integrated Stress Response (ISR) is a Focal Point of Tumorigenic Pathways in Krasdriven Lung Cancer N Ghaddar McGill University (Canada), 2022 | | 2022 |
