| Bisubstrate inhibitors of protein kinases: from principle to practical applications D Lavogina, E Enkvist, A Uri ChemMedChem: Chemistry Enabling Drug Discovery 5 (1), 23-34, 2010 | 137 | 2010 |
| Conjugation of adenosine and hexa-(D-arginine) leads to a nanomolar bisubstrate-analog inhibitor of basophilic protein kinases E Enkvist, D Lavogina, G Raidaru, A Vaasa, I Viil, M Lust, K Viht, A Uri Journal of medicinal chemistry 49 (24), 7150-7159, 2006 | 82 | 2006 |
| High-affinity bisubstrate probe for fluorescence anisotropy binding/displacement assays with protein kinases PKA and ROCK A Vaasa, I Viil, E Enkvist, K Viht, G Raidaru, D Lavogina, A Uri Analytical biochemistry 385 (1), 85-93, 2009 | 78 | 2009 |
| Protein-induced long lifetime luminescence of nonmetal probes E Enkvist, A Vaasa, M Kasari, M Kriisa, T Ivan, K Ligi, G Raidaru, A Uri ACS chemical biology 6 (10), 1052-1062, 2011 | 56 | 2011 |
| Structural analysis of ARC-type inhibitor (ARC-1034) binding to protein kinase A catalytic subunit and rational design of bisubstrate analogue inhibitors of basophilic protein … D Lavogina, M Lust, I Viil, N Konig, G Raidaru, J Rogozina, E Enkvist, ... Journal of medicinal chemistry 52 (2), 308-321, 2009 | 56 | 2009 |
| A subnanomolar fluorescent probe for protein kinase CK2 interaction studies E Enkvist, K Viht, N Bischoff, J Vahter, S Saaver, G Raidaru, OG Issinger, ... Organic & biomolecular chemistry 10 (43), 8645-8653, 2012 | 45 | 2012 |
| Diversity of bisubstrate binding modes of adenosine analogue–oligoarginine conjugates in protein kinase A and implications for protein substrate interactions A Pflug, J Rogozina, D Lavogina, E Enkvist, A Uri, RA Engh, ... Journal of molecular biology 403 (1), 66-77, 2010 | 44 | 2010 |
| Fluorometric TLC assay for evaluation of protein kinase inhibitors K Viht, A Vaasa, G Raidaru, E Enkvist, A Uri Analytical biochemistry 340 (1), 165-170, 2005 | 35 | 2005 |
| Acetoxymethyl Ester of Tetrabromobenzimidazole–Peptoid Conjugate for Inhibition of Protein Kinase CK2 in Living Cells K Viht, S Saaver, J Vahter, E Enkvist, D Lavogina, H Sinijärv, G Raidaru, ... Bioconjugate chemistry 26 (12), 2324-2335, 2015 | 31 | 2015 |
| Time-gated luminescence microscopy with responsive nonmetal probes for mapping activity of protein kinases in living cells A Vaasa, K Ligi, S Mohandessi, E Enkvist, A Uri, LW Miller Chemical communications 48 (68), 8595-8597, 2012 | 28 | 2012 |
| Benzoselenadiazole-based responsive long-lifetime photoluminescent probes for protein kinases R Ekambaram, E Enkvist, G babu Manoharan, M Ugandi, M Kasari, K Viht, ... Chemical communications 50 (31), 4096-4098, 2014 | 25 | 2014 |
| Responsive microsecond-lifetime photoluminescent probes for analysis of protein kinases and their inhibitors M Kasari, K Ligi, JAG Williams, A Vaasa, E Enkvist, K Viht, LO Pålsson, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1834 (7), 1330-1335, 2013 | 25 | 2013 |
| Selective Bisubstrate Inhibitors with Sub‐nanomolar Affinity for Protein Kinase Pim‐1 R Ekambaram, E Enkvist, A Vaasa, M Kasari, G Raidaru, S Knapp, A Uri ChemMedChem 8 (6), 909-913, 2013 | 25 | 2013 |
| Bisubstrate fluorescent probes and biosensors in binding assays for HTS of protein kinase inhibitors A Uri, M Lust, A Vaasa, D Lavogina, K Viht, E Enkvist Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1804 (3), 541-546, 2010 | 24 | 2010 |
| A selective biligand inhibitor of CK2 increases caspase‐3 activity in cancer cells and inhibits platelet aggregation H Rahnel, K Viht, D Lavogina, O Mazina, T Haljasorg, E Enkvist, A Uri ChemMedChem 12 (20), 1723-1736, 2017 | 23 | 2017 |
| Bifunctional ligands for inhibition of tight-binding protein–protein interactions T Ivan, E Enkvist, B Viira, GB Manoharan, G Raidaru, A Pflug, KA Alam, ... Bioconjugate Chemistry 27 (8), 1900-1910, 2016 | 21 | 2016 |
| Conjugates of 5-isoquinolinesulfonylamides and oligo-D-arginine possess high affinity and selectivity towards Rho kinase (ROCK) D Lavogina, K Kalind, J Bredihhina, M Hurt, A Vaasa, M Kasari, E Enkvist, ... Bioorganic & medicinal chemistry letters 22 (10), 3425-3430, 2012 | 21 | 2012 |
| Carbocyclic 3′-deoxyadenosine-based highly potent bisubstrate-analog inhibitor of basophilic protein kinases E Enkvist, G Raidaru, A Vaasa, T Pehk, D Lavogina, A Uri Bioorganic & medicinal chemistry letters 17 (19), 5336-5339, 2007 | 21 | 2007 |
| Unexpected CK2β-antagonistic functionality of bisubstrate inhibitors targeting protein kinase CK2 M Pietsch, K Viht, A Schnitzler, R Ekambaram, M Steinkrueger, E Enkvist, ... Bioorganic Chemistry 96, 103608, 2020 | 20 | 2020 |
| Thiazole-and selenazole-comprising high-affinity inhibitors possess bright microsecond-scale photoluminescence in complex with protein kinase CK2 J Vahter, K Viht, A Uri, G babu Manoharan, E Enkvist Bioorganic & medicinal chemistry 26 (18), 5062-5068, 2018 | 17 | 2018 |
