Lipidic prodrug approach for improved oral drug delivery and therapy M Markovic, S Ben‐Shabat, S Keinan, A Aponick, EM Zimmermann, ... Medicinal research reviews 39 (2), 579-607, 2019 | 75 | 2019 |
Prodrugs for Improved Drug Delivery: Lessons Learned from Recently Developed and Marketed Products M Markovic, S Ben-Shabat, A Dahan Pharmaceutics 12 (11), 1031, 2020 | 64 | 2020 |
Lipids and lipid-processing pathways in drug delivery and therapeutics M Markovic, S Ben-Shabat, A Aponick, EM Zimmermann, A Dahan International journal of molecular sciences 21 (9), 3248, 2020 | 64 | 2020 |
BCS Class IV Oral Drugs and Absorption Windows: Regional-Dependent Intestinal Permeability of Furosemide M Markovic, M Zur, I Ragatsky, S Cvijić, A Dahan Pharmaceutics 12 (12), 1175, 2020 | 37 | 2020 |
Investigating drug absorption from the colon: Single-pass vs. Doluisio approaches to in-situ rat large-intestinal perfusion I Lozoya-Agullo, M Zur, N Fine-Shamir, M Markovic, Y Cohen, D Porat, ... International journal of pharmaceutics 527 (1-2), 135-141, 2017 | 36 | 2017 |
Phospholipid-drug conjugates as a novel oral drug targeting approach for the treatment of inflammatory bowel disease A Dahan, M Markovic, S Epstein, N Cohen, EM Zimmermann, A Aponick, ... European Journal of Pharmaceutical Sciences 108, 78-85, 2017 | 35 | 2017 |
Closed-loop doluisio (colon, small intestine) and single-pass intestinal perfusion (colon, jejunum) in rat—Biophysical model and predictions based on Caco-2 I Lozoya-Agullo, I Gonzalez-Alvarez, M Zur, N Fine-Shamir, Y Cohen, ... Pharmaceutical research 35 (1), 2, 2018 | 32 | 2018 |
Prospects and challenges of phospholipid-based prodrugs M Markovic, S Ben-Shabat, S Keinan, A Aponick, EM Zimmermann, ... Pharmaceutics 10 (4), 210, 2018 | 29 | 2018 |
Transformation of dolutegravir into an ultra-long-acting parenteral prodrug formulation S Deodhar, B Sillman, AN Bade, SN Avedissian, AT Podany, ... Nature communications 13 (1), 3226, 2022 | 24 | 2022 |
Biopharmaceutical characterization of rebamipide: The role of mucus binding in regional-dependent intestinal permeability M Markovic, M Zur, A Dahan, S Cvijić European Journal of Pharmaceutical Sciences 152, 105440, 2020 | 24 | 2020 |
Increased paracetamol bioavailability after sleeve gastrectomy: A crossover pre-vs. post-operative clinical trial D Porat, M Markovic, M Zur, N Fine-Shamir, C Azran, G Shaked, ... Journal of clinical medicine 8 (11), 1949, 2019 | 24 | 2019 |
Phospholipid-based prodrugs for colon-targeted drug delivery: experimental study and in-silico simulations M Markovic, A Dahan, S Keinan, I Kurnikov, A Aponick, EM Zimmermann, ... Pharmaceutics 11 (4), 186, 2019 | 24 | 2019 |
Humanized mice for infectious and neurodegenerative disorders PK Dash, S Gorantla, L Poluektova, M Hasan, E Waight, C Zhang, ... Retrovirology 18 (1), 13, 2021 | 23 | 2021 |
Molecular modeling-guided design of phospholipid-based prodrugs M Markovic, S Ben-Shabat, S Keinan, A Aponick, EM Zimmermann, ... International journal of molecular sciences 20 (9), 2210, 2019 | 23 | 2019 |
Segmental-dependent intestinal drug permeability: Development and model validation of in silico predictions guided by in vivo permeability values O Wolk, M Markovic, D Porat, N Fine-Shamir, M Zur, A Beig, A Dahan Journal of pharmaceutical sciences 108 (1), 316-325, 2019 | 21 | 2019 |
Computational simulations to guide enzyme-mediated prodrug activation M Markovic, S Ben-Shabat, A Dahan International Journal of Molecular Sciences 21 (10), 3621, 2020 | 19 | 2020 |
Segmental-dependent solubility and permeability as key factors guiding controlled release drug product development M Markovic, M Zur, N Fine-Shamir, E Haimov, I González-Álvarez, ... Pharmaceutics 12 (3), 295, 2020 | 18 | 2020 |
Computational modeling and in-vitro/in-silico correlation of phospholipid-based prodrugs for targeted drug delivery in inflammatory bowel disease A Dahan, M Markovic, S Keinan, I Kurnikov, A Aponick, EM Zimmermann, ... Journal of Computer-Aided Molecular Design 31, 1021-1028, 2017 | 18 | 2017 |
Europium-doped cerium oxide nanoparticles for microglial amyloid beta clearance and homeostasis J Machhi, P Yeapuri, M Markovic, M Patel, W Yan, Y Lu, JD Cohen, ... ACS Chemical Neuroscience 13 (8), 1232-1244, 2022 | 17 | 2022 |
The prospects of lipidic prodrugs: an old approach with an emerging future A Dahan, M Markovic, A Aponick, EM Zimmermann, S Ben-Shabat Future medicinal chemistry 11 (19), 2563-2571, 2019 | 16 | 2019 |