Molecular architecture of 4E-BP translational inhibitors bound to eIF4E D Peter, C Igreja, R Weber, L Wohlbold, C Weiler, L Ebertsch, ... Molecular cell 57 (6), 1074-1087, 2015 | 183 | 2015 |
The structures of eIF4E-eIF4G complexes reveal an extended interface to regulate translation initiation S Grüner, D Peter, R Weber, L Wohlbold, MY Chung, O Weichenrieder, ... Molecular cell 64 (3), 467-479, 2016 | 126 | 2016 |
CUP promotes deadenylation and inhibits decapping of mRNA targets C Igreja, E Izaurralde Genes & development 25 (18), 1955-1967, 2011 | 105 | 2011 |
Characterization and clinical relevance of circulating and biopsy-derived endothelial progenitor cells in lymphoma patients C Igreja, M Courinha, AS Cachaço, T Pereira, J Cabeçadas, MG da Silva, ... Haematologica 92 (4), 469-477, 2007 | 96 | 2007 |
HPat provides a link between deadenylation and decapping in metazoa G Haas, JE Braun, C Igreja, F Tritschler, T Nishihara, E Izaurralde Journal of Cell Biology 189 (2), 289-302, 2010 | 93 | 2010 |
4E-BPs require non-canonical 4E-binding motifs and a lateral surface of eIF4E to repress translation C Igreja, D Peter, C Weiler, E Izaurralde Nature communications 5 (1), 4790, 2014 | 90 | 2014 |
GIGYF1/2 proteins use auxiliary sequences to selectively bind to 4EHP and repress target mRNA expression D Peter, R Weber, F Sandmeir, L Wohlbold, S Helms, P Bawankar, ... Genes & Development 31 (11), 1147-1161, 2017 | 81 | 2017 |
DCP1 forms asymmetric trimers to assemble into active mRNA decapping complexes in metazoa F Tritschler, JE Braun, C Motz, C Igreja, G Haas, V Truffault, E Izaurralde, ... Proceedings of the National Academy of Sciences 106 (51), 21591-21596, 2009 | 80 | 2009 |
The C‐terminal α–α superhelix of Pat is required for mRNA decapping in metazoa JE Braun, F Tritschler, G Haas, C Igreja, V Truffault, O Weichenrieder, ... The EMBO journal 29 (14), 2368-2380, 2010 | 68 | 2010 |
TNF-α regulates the effects of irradiation in the mouse bone marrow microenvironment AS Cachaço, T Carvalho, AC Santos, C Igreja, R Fragoso, C Osório, ... PloS one 5 (2), e8980, 2010 | 56 | 2010 |
4E-T-bound mRNAs are stored in a silenced and deadenylated form F Räsch, R Weber, E Izaurralde, C Igreja Genes & development 34 (11-12), 847-860, 2020 | 51 | 2020 |
4EHP and GIGYF1/2 mediate translation-coupled messenger RNA decay R Weber, MY Chung, C Keskeny, U Zinnall, M Landthaler, E Valkov, ... Cell reports 33 (2), 2020 | 48 | 2020 |
Detailed molecular characterization of cord blood–derived endothelial progenitors C Igreja, R Fragoso, F Caiado, N Clode, A Henriques, L Camargo, ... Experimental hematology 36 (2), 193. e1-193. e15, 2008 | 48 | 2008 |
Structural motifs in eIF4G and 4E-BPs modulate their binding to eIF4E to regulate translation initiation in yeast S Grüner, R Weber, D Peter, MY Chung, C Igreja, E Valkov, E Izaurralde Nucleic acids research 46 (13), 6893-6908, 2018 | 41 | 2018 |
A conserved CAF40-binding motif in metazoan NOT4 mediates association with the CCR4–NOT complex C Keskeny, T Raisch, A Sgromo, C Igreja, D Bhandari, O Weichenrieder, ... Genes & Development 33 (3-4), 236-252, 2019 | 38 | 2019 |
A low-complexity region in human XRN1 directly recruits deadenylation and decapping factors in 5′–3′ messenger RNA decay CT Chang, S Muthukumar, R Weber, Y Levdansky, Y Chen, D Bhandari, ... Nucleic Acids Research 47 (17), 9282-9295, 2019 | 31 | 2019 |
Molecular basis for GIGYF–Me31B complex assembly in 4EHP-mediated translational repression D Peter, V Ruscica, P Bawankar, R Weber, S Helms, E Valkov, C Igreja, ... Genes & Development 33 (19-20), 1355-1360, 2019 | 30 | 2019 |
Direct role for the Drosophila GIGYF protein in 4EHP-mediated mRNA repression V Ruscica, P Bawankar, D Peter, S Helms, C Igreja, E Izaurralde Nucleic acids research 47 (13), 7035-7048, 2019 | 29 | 2019 |
Mextli proteins use both canonical bipartite and novel tripartite binding modes to form eIF4E complexes that display differential sensitivity to 4E-BP regulation D Peter, R Weber, C Köne, MY Chung, L Ebertsch, V Truffault, ... Genes & development 29 (17), 1835-1849, 2015 | 29 | 2015 |
eIF4E-homologous protein (4EHP): a multifarious cap-binding protein M Christie, C Igreja Febs j 290, 266-285, 2021 | 28 | 2021 |