The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease JM Shillingford, NS Murcia, CH Larson, SH Low, R Hedgepeth, N Brown, ... Proceedings of the National Academy of Sciences 103 (14), 5466-5471, 2006 | 977 | 2006 |
Polycystin-1, STAT6, and P100 function in a pathway that transduces ciliary mechanosensation and is activated in polycystic kidney disease SH Low, S Vasanth, CH Larson, S Mukherjee, N Sharma, MT Kinter, ... Developmental cell 10 (1), 57-69, 2006 | 433 | 2006 |
A conserved domain is present in different families of vesicular fusion proteins: a new superfamily T Weimbs, SH Low, SJ Chapin, KE Mostov, P Bucher, K Hofmann Proceedings of the National Academy of Sciences 94 (7), 3046-3051, 1997 | 379 | 1997 |
Rapamycin ameliorates PKD resulting from conditional inactivation of Pkd1 JM Shillingford, KB Piontek, GG Germino, T Weimbs Journal of the American Society of Nephrology 21 (3), 489-497, 2010 | 307 | 2010 |
Proteolipid protein (PLP) of CNS myelin: positions of free, disulfide-bonded, and fatty acid thioester-linked cysteine residues and implications for the membrane topology of PLP T Weimbs, W Stoffel Biochemistry 31 (49), 12289-12296, 1992 | 279 | 1992 |
Three-dimensional analysis of post-Golgi carrier exocytosis in epithelial cells G Kreitzer, J Schmoranzer, SH Low, X Li, Y Gan, T Weimbs, SM Simon, ... Nature cell biology 5 (2), 126-136, 2003 | 260 | 2003 |
Differential localization of syntaxin isoforms in polarized Madin-Darby canine kidney cells. SH Low, SJ Chapin, T Weimbs, LG Kömüves, MK Bennett, KE Mostov Molecular biology of the cell 7 (12), 2007-2018, 1996 | 260 | 1996 |
Polarity proteins control ciliogenesis via kinesin motor interactions S Fan, TW Hurd, CJ Liu, SW Straight, T Weimbs, EA Hurd, SE Domino, ... Current biology 14 (16), 1451-1461, 2004 | 254 | 2004 |
Syntaxin 2 and endobrevin are required for the terminal step of cytokinesis in mammalian cells SH Low, X Li, M Miura, N Kudo, B Quiñones, T Weimbs Developmental cell 4 (5), 753-759, 2003 | 226 | 2003 |
The SNARE machinery is involved in apical plasma membrane trafficking in MDCK cells SH Low, SJ Chapin, C Wimmer, SW Whiteheart, LG Kömüves, KE Mostov, ... The Journal of cell biology 141 (7), 1503-1513, 1998 | 202 | 1998 |
A model for structural similarity between different SNARE complexes based on sequence relationships T Weimbs, K Mostov, SH Low, K Hofmann Trends in cell biology 8 (7), 260-262, 1998 | 180 | 1998 |
Ketosis ameliorates renal cyst growth in polycystic kidney disease JA Torres, SL Kruger, C Broderick, T Amarlkhagva, S Agrawal, JR Dodam, ... Cell metabolism 30 (6), 1007-1023. e5, 2019 | 171 | 2019 |
Polycystin-1 regulates STAT activity by a dual mechanism JJ Talbot, JM Shillingford, S Vasanth, N Doerr, S Mukherjee, MT Kinter, ... Proceedings of the National Academy of Sciences 108 (19), 7985-7990, 2011 | 157 | 2011 |
Polycystic kidney disease and renal injury repair: common pathways, fluid flow, and the function of polycystin-1 T Weimbs American Journal of Physiology-Renal Physiology 293 (5), F1423-F1432, 2007 | 148 | 2007 |
Apical targeting in polarized epithelial cells: there's more afloat than rafts T Weimbs, SH Low, SJ Chapin, KE Mostov Trends in cell biology 7 (10), 393-399, 1997 | 131 | 1997 |
Folate-conjugated rapamycin slows progression of polycystic kidney disease JM Shillingford, CP Leamon, IR Vlahov, T Weimbs Journal of the American Society of Nephrology 23 (10), 1674-1681, 2012 | 127 | 2012 |
Prospects for mTOR inhibitor use in patients with polycystic kidney disease and hamartomatous diseases VE Torres, A Boletta, A Chapman, V Gattone, Y Pei, Q Qian, DP Wallace, ... Clinical Journal of the American Society of Nephrology 5 (7), 1312-1329, 2010 | 121 | 2010 |
Targeting of SNAP-23 and SNAP-25 in polarized epithelial cells SH Low, PA Roche, HA Anderson, SCD van Ijzendoorn, M Zhang, ... Journal of Biological Chemistry 273 (6), 3422-3430, 1998 | 116 | 1998 |
Apical targeting of syntaxin 3 is essential for epithelial cell polarity N Sharma, SH Low, S Misra, B Pallavi, T Weimbs The Journal of cell biology 173 (6), 937-948, 2006 | 113 | 2006 |
Syntaxins 3 and 4 are concentrated in separate clusters on the plasma membrane before the establishment of cell polarity SH Low, A Vasanji, J Nanduri, M He, N Sharma, M Koo, J Drazba, ... Molecular biology of the cell 17 (2), 977-989, 2006 | 101 | 2006 |