Chronic infection drives Dnmt3a-loss-of-function clonal hematopoiesis via IFNγ signaling D Hormaechea-Agulla, KA Matatall, DT Le, B Kain, X Long, P Kus, ... Cell stem cell 28 (8), 1428-1442. e6, 2021 | 215 | 2021 |
Yin and Yang: The dual effects of interferons on hematopoiesis Y Demerdash, B Kain, MAG Essers, KY King Experimental hematology 96, 1-12, 2021 | 52 | 2021 |
Compromised catalysis and potential folding defects in in vitro studies of missense mutants associated with hereditary phosphoglucomutase 1 deficiency Y Lee, KM Stiers, BN Kain, LJ Beamer Journal of Biological Chemistry 289 (46), 32010-32019, 2014 | 51 | 2014 |
Induced structural disorder as a molecular mechanism for enzyme dysfunction in phosphoglucomutase 1 deficiency KM Stiers, BN Kain, AC Graham, LJ Beamer Journal of molecular biology 428 (8), 1493-1505, 2016 | 24 | 2016 |
Hematopoietic stem and progenitor cells improve survival from sepsis by boosting immunomodulatory cells DE Morales-Mantilla, B Kain, D Le, AR Flores, S Paust, KY King elife 11, e74561, 2022 | 17 | 2022 |
Asp263 missense variants perturb the active site of human phosphoglucomutase 1 KM Stiers, AC Graham, BN Kain, LJ Beamer The FEBS journal 284 (6), 937-947, 2017 | 14 | 2017 |
An immunophenotype-coupled transcriptomic atlas of human hematopoietic progenitors X Zhang, B Song, MJ Carlino, G Li, K Ferchen, M Chen, EN Thompson, ... Nature Immunology 25 (4), 703-715, 2024 | 6 | 2024 |
Hematopoietic stem and progenitor cells confer cross-protective trained immunity in mouse models BN Kain, BT Tran, PN Luna, R Cao, DT Le, MA Florez, L Maneix, ... Iscience 26 (9), 2023 | 6 | 2023 |
BATF2 promotes HSC myeloid differentiation by amplifying IFN response mediators during chronic infection DT Le, MA Florez, P Kus, BT Tran, B Kain, Y Zhu, K Christensen, A Jain, ... Iscience 26 (2), 2023 | 3 | 2023 |
Hematopoietic stem cells undergo immune training and constitute a long-term reservoir for hyper-inflammatory macrophages in a mouse model of chronic autoimmunity TS Mills, BN Kain, ED Lucas, MT Burchill, BAJ Tamburini, KY King, ... Blood 138, 2165, 2021 | 2 | 2021 |
Specificity and heterogeneity of trained immunity in hematopoietic stem and progenitor cells BN Kain, P Luna, D Hormaechea Agulla, L Maneix, DE Morales-Mantilla, ... Blood 138 (Supplement 1), 2149-2149, 2021 | 2 | 2021 |
Infection is a driver of dnmt3a-mutant clonal hematopoiesis DH Agulla, KA Matatall, D Le, BN Kain, R Jaksik, M Kimmel, G Challen, ... Blood 134, 817, 2019 | 2 | 2019 |
Genomic Profiles and Associated Survival Prognosticators in Black Patients with Acute Myeloid Leukemia A Stiff, D Nicolet, M Fornerod, B Kelly, K Miller, K Mrózek, I Boateng, ... Blood 142 (Supplement 1), 837-837, 2023 | 1 | 2023 |
Hematopoietic Stem and Progenitor Cell Trained Immunity Is Heterogeneous and Cross-Protective in a Mouse Model of M. Avium Infection BN Kain, B Tran, P Luna, R Cao, D Le, MA Florez, L Maneix, J Toups, ... Blood 142 (Supplement 1), 1296-1296, 2023 | | 2023 |
3222–CLONAL COMPETITION: CHEMOTHERAPEUTIC STRESS DRIVES DOMINANCE OF TP53-OVER TET2-MUTANT STEM CELL CLONES K Wohlan, L Brunetti, J Hsu, K Matatall, R Murdaugh, L Zhang, A Guzman, ... Experimental Hematology 124, S160, 2023 | | 2023 |
3202–M. AVIUM INDUCES EPIGENETIC REPROGRAMMED HSPC-TRAINED IMMUNITY THAT ALTERS DOWNSTREAM MYELOID IMMUNE FUNCTION. B Tran, B Kain, R Cao, S Koh, K King Experimental Hematology 124, S150, 2023 | | 2023 |
3192–DEFINING THE MECHANISMS OF BST2 IN INFLAMMATION-DEPENDENT HEMATOPOIETIC STEM CELL ACTIVATION A Thatavarty, M Florez, D Le, Y Jeong, B Ho, P Kus, T Wathan, B Kain, ... Experimental Hematology 124, S145, 2023 | | 2023 |
Clonal Competition: Cisplatin Treatment Drives Dominance of TP53-over Tet2-Mutant Stem Cell Clones K Wohlan, L Brunetti, JI Hsu, KA Matatall, RL Murdaugh, L Zhang, ... Blood 140 (Supplement 1), 8590-8591, 2022 | | 2022 |
BATF2 Promotes HSC Myeloid Differentiation Via Amplification of the Pro-Inflammatory Response during Chronic Infection D Le, MA Florez, P Kus, B Tran, BN Kain, A Jain, A Malovannaya, KY King Blood 140 (Supplement 1), 5732-5733, 2022 | | 2022 |
Hematopoietic stem cells are a reservoir for trained immunity in autoimmune disease TS Mills, B Kain, MA Burchill, E Danis, R Culp-Hill, A Goodspeed, ... bioRxiv, 2022.05. 20.492533, 2022 | | 2022 |