| Onco-fetal Reprogramming of Endothelial Cells Drives Immunosuppressive Macrophages in Hepatocellular Carcinoma A Sharma, JJW Seow, CA Dutertre, R Pai, C Blériot, A Mishra, RMM Wong, ... Cell 183 (2), 377-394. e21, 2020 | 393 | 2020 |
| Cross-tissue single-cell landscape of human monocytes and macrophages in health and disease K Mulder, AA Patel, WT Kong, C Piot, E Halitzki, G Dunsmore, ... Immunity 54 (8), 1883-1900. e5, 2021 | 309 | 2021 |
| Microbial exposure during early human development primes fetal immune cells A Mishra, GC Lai, LJ Yao, TT Aung, N Shental, A Rotter-Maskowitz, ... Cell 184 (13), 3394-3409. e20, 2021 | 184 | 2021 |
| Longitudinal single-cell RNA sequencing of patient-derived primary cells reveals drug-induced infidelity in stem cell hierarchy A Sharma, EY Cao, V Kumar, X Zhang, HS Leong, AML Wong, ... Nature communications 9 (1), 4931, 2018 | 146 | 2018 |
| A subset of Kupffer cells regulates metabolism through the expression of CD36 C Blériot, E Barreby, G Dunsmore, R Ballaire, S Chakarov, X Ficht, ... Immunity 54 (9), 2101-2116. e6, 2021 | 123 | 2021 |
| Taurine deficiency as a driver of aging P Singh, K Gollapalli, S Mangiola, D Schranner, MA Yusuf, M Chamoli, ... Science 380 (6649), eabn9257, 2023 | 120 | 2023 |
| A Monoclonal Antibody against Human Notch1 Ligand–Binding Domain Depletes Subpopulation of Putative Breast Cancer Stem–like Cells A Sharma, AN Paranjape, A Rangarajan, RR Dighe Molecular Cancer Therapeutics 11 (1), 77-86, 2012 | 110 | 2012 |
| Phenotype-driven precision oncology as a guide for clinical decisions one patient at a time Nature Communications 8 (435), 10.1038/s41467-017-00451-5, 2017 | 85* | 2017 |
| SpDamID: Marking DNA Bound by Protein Complexes Identifies Notch-Dimer Responsive Enhancers MR Hass, H Liow, X Chen, A Sharma, YU Inoue, T Inoue, A Reeb, ... Molecular cell 59 (4), 685-697, 2015 | 65 | 2015 |
| Coordinate hyperactivation of Notch1 and Ras/MAPK pathways correlates with poor patient survival: novel therapeutic strategy for aggressive breast cancers S Mittal, A Sharma, SA Balaji, MC Gowda, RR Dighe, RV Kumar, ... Molecular cancer therapeutics 13 (12), 3198-3209, 2014 | 61 | 2014 |
| A novel monoclonal antibody against Notch1 targets leukemia-associated mutant Notch1 and depletes therapy resistant cancer stem cells in solid tumors A Sharma, RA Gadkari, SV Ramakanth, K Padmanabhan, ... Scientific reports 5 (1), 11012, 2015 | 37 | 2015 |
| Oncofetal reprogramming in tumour development and progression A Sharma, C Blériot, J Currenti, F Ginhoux Nature Reviews Cancer 22 (10), 593-602, 2022 | 33 | 2022 |
| Predicting heterogeneity in clone-specific therapeutic vulnerabilities using single-cell transcriptomic signatures C Suphavilai, S Chia, A Sharma, L Tu, RP Da Silva, A Mongia, ... Genome Medicine 13, 1-14, 2021 | 33 | 2021 |
| Antibodies against the extracellular domain of human Notch1 receptor reveal the critical role of EGF like repeats 25-26 in the ligand binding and receptor activation A Sharma, A Rangarajan, RR Dighe Biochemical Journal, 2012 | 29* | 2012 |
| scRNA-seq reveals ACE2 and TMPRSS2 expression in TROP2+ Liver Progenitor Cells: Implications in COVID-19 associated Liver Dysfunction JJ Wen Seow, R Pai, A Mishra, E Shepherdson, TK Hon Lim, BKP Goh, ... BioRxiv, 2020.03. 23.002832, 2020 | 27 | 2020 |
| Single-Cell RNA-seq Reveals Angiotensin-Converting Enzyme 2 and Transmembrane Serine Protease 2 Expression in TROP2+ Liver Progenitor Cells … JJW Seow, R Pai, A Mishra, E Shepherdson, TKH Lim, BKP Goh, ... Frontiers in medicine 8, 603374, 2021 | 23 | 2021 |
| Deterministic reprogramming of neutrophils within tumors MSF Ng, I Kwok, L Tan, C Shi, D Cerezo-Wallis, Y Tan, K Leong, ... Science 383 (6679), eadf6493, 2024 | 20 | 2024 |
| Single‐Cell RNA Sequencing for Precision Oncology: Current State-of-Art JJW Seow, RMM Wong, R Pai, A Sharma Journal of the Indian Institute of Science 100, 579-588, 2020 | 13 | 2020 |
| Single-cell analysis of EphA clustering phenotypes to probe cancer cell heterogeneity A Ravasio, MZ Myaing, S Chia, A Arora, A Sathe, EY Cao, C Bertocchi, ... Communications Biology 3 (1), 429, 2020 | 12 | 2020 |
| Presence of onco-fetal neighborhoods in hepatocellular carcinoma is associated with relapse and response to immunotherapy Z Li, R Pai, S Gupta, J Currenti, W Guo, A Di Bartolomeo, H Feng, Z Zhang, ... Nature Cancer, 1-20, 2024 | 10 | 2024 |
Rhea PaiHarry Perkins Institute of Medical Research & Curtin University在 postgrad.curtin.edu.au 的电子邮件经过验证
