Differential regulation of mTORC1 by leucine and glutamine JL Jewell, YC Kim, RC Russell, FX Yu, HW Park, SW Plouffe, ... Science 347 (6218), 194-198, 2015 | 724 | 2015 |
Alternative Wnt signaling activates YAP/TAZ HW Park, YC Kim, BO Yu, T Moroishi, JS Mo, SW Plouffe, Z Meng, KC Lin, ... Cell 162 (4), 780-794, 2015 | 675 | 2015 |
MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway Z Meng, T Moroishi, V Mottier-Pavie, SW Plouffe, CG Hansen, AW Hong, ... Nature communications 6 (1), 8357, 2015 | 492 | 2015 |
A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis T Moroishi, HW Park, B Qin, Q Chen, Z Meng, SW Plouffe, K Taniguchi, ... Genes & development 29 (12), 1271-1284, 2015 | 336 | 2015 |
RAP2 mediates mechanoresponses of the Hippo pathway Z Meng, Y Qiu, KC Lin, A Kumar, JK Placone, C Fang, KC Wang, S Lu, ... Nature 560 (7720), 655-660, 2018 | 317 | 2018 |
Characterization of Hippo pathway components by gene inactivation SW Plouffe, Z Meng, KC Lin, B Lin, AW Hong, JV Chun, KL Guan Molecular cell 64 (5), 993-1008, 2016 | 258 | 2016 |
Disease implications of the Hippo/YAP pathway SW Plouffe, AW Hong, KL Guan Trends in molecular medicine 21 (4), 212-222, 2015 | 232 | 2015 |
The Hippo pathway effector proteins YAP and TAZ have both distinct and overlapping functions in the cell SW Plouffe, KC Lin, JL Moore, FE Tan, S Ma, Z Ye, Y Qiu, B Ren, KL Guan Journal of Biological Chemistry 293 (28), 11230-11240, 2018 | 228 | 2018 |
The Hippo pathway in organ development, homeostasis, and regeneration V Fu, SW Plouffe, KL Guan Current opinion in cell biology 49, 99-107, 2017 | 209 | 2017 |
Regulation of Hippo pathway transcription factor TEAD by p38 MAPK-induced cytoplasmic translocation KC Lin, T Moroishi, Z Meng, HS Jeong, SW Plouffe, Y Sekido, J Han, ... Nature cell biology 19 (8), 996-1002, 2017 | 192 | 2017 |
The Hippo pathway effectors YAP and TAZ promote cell growth by modulating amino acid signaling to mTORC1 CG Hansen, YLD Ng, WLM Lam, SW Plouffe, KL Guan Cell research 25 (12), 1299-1313, 2015 | 189 | 2015 |
Hippo signalling governs cytosolic nucleic acid sensing through YAP/TAZ-mediated TBK1 blockade Q Zhang, F Meng, S Chen, SW Plouffe, S Wu, S Liu, X Li, R Zhou, J Wang, ... Nature cell biology 19 (4), 362-374, 2017 | 174 | 2017 |
Osmotic stress‐induced phosphorylation by NLK at Ser128 activates YAP AW Hong, Z Meng, HX Yuan, SW Plouffe, S Moon, W Kim, E Jho, KL Guan EMBO reports 18 (1), 72-86, 2017 | 138 | 2017 |
Hippo pathway regulation of gastrointestinal tissues FX Yu, Z Meng, SW Plouffe, KL Guan Annual review of physiology 77 (1), 201-227, 2015 | 133 | 2015 |
Induction of AP-1 by YAP/TAZ contributes to cell proliferation and organ growth JH Koo, SW Plouffe, Z Meng, DH Lee, D Yang, DS Lim, CY Wang, ... Genes & development 34 (1-2), 72-86, 2020 | 94 | 2020 |
Mst1 shuts off cytosolic antiviral defense through IRF3 phosphorylation F Meng, R Zhou, S Wu, Q Zhang, Q Jin, Y Zhou, SW Plouffe, S Liu, ... Genes & Development 30 (9), 1086-1100, 2016 | 83 | 2016 |
YAP and MRTF-A, transcriptional co-activators of RhoA-mediated gene expression, are critical for glioblastoma tumorigenicity OM Yu, JA Benitez, SW Plouffe, D Ryback, A Klein, J Smith, J Greenbaum, ... Oncogene 37 (41), 5492-5507, 2018 | 61 | 2018 |
Opposing roles of conventional and novel PKC isoforms in Hippo-YAP pathway regulation R Gong, AW Hong, SW Plouffe, B Zhao, G Liu, FX Yu, Y Xu, KL Guan Cell research 25 (8), 985-988, 2015 | 54 | 2015 |
Critical roles of phosphoinositides and NF2 in Hippo pathway regulation AW Hong, Z Meng, SW Plouffe, Z Lin, M Zhang, KL Guan Genes & development 34 (7-8), 511-525, 2020 | 44 | 2020 |
Molecular basis of transcriptional fidelity and DNA lesion-induced transcriptional mutagenesis L Xu, L Da, SW Plouffe, J Chong, E Kool, D Wang DNA repair 19, 71-83, 2014 | 33 | 2014 |