Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity LC Tsoi, SL Spain, J Knight, E Ellinghaus, PE Stuart, F Capon, J Ding, ... Nature genetics 44 (12), 1341-1348, 2012 | 1073 | 2012 |
Atopic dermatitis is an IL-13–dominant disease with greater molecular heterogeneity compared to psoriasis LC Tsoi, E Rodriguez, F Degenhardt, H Baurecht, U Wehkamp, N Volks, ... Journal of Investigative Dermatology 139 (7), 1480-1489, 2019 | 396 | 2019 |
Transcriptome analysis of psoriasis in a large case–control sample: RNA-seq provides insights into disease mechanisms B Li, LC Tsoi, WR Swindell, JE Gudjonsson, T Tejasvi, A Johnston, J Ding, ... Journal of Investigative Dermatology 134 (7), 1828-1838, 2014 | 393 | 2014 |
Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants LC Tsoi, PE Stuart, C Tian, JE Gudjonsson, S Das, M Zawistowski, ... Nature communications 8 (1), 15382, 2017 | 350 | 2017 |
Genome-wide association analysis of psoriatic arthritis and cutaneous psoriasis reveals differences in their genetic architecture PE Stuart, RP Nair, LC Tsoi, T Tejasvi, S Das, HM Kang, E Ellinghaus, ... The American Journal of Human Genetics 97 (6), 816-836, 2015 | 328 | 2015 |
Psoriasis: a mixed autoimmune and autoinflammatory disease Y Liang, MK Sarkar, LC Tsoi, JE Gudjonsson Current opinion in immunology 49, 1-8, 2017 | 262 | 2017 |
Analysis of long non-coding RNAs highlights tissue-specific expression patterns and epigenetic profiles in normal and psoriatic skin LC Tsoi, MK Iyer, PE Stuart, WR Swindell, JE Gudjonsson, T Tejasvi, ... Genome biology 16, 1-15, 2015 | 238 | 2015 |
Fine mapping major histocompatibility complex associations in psoriasis and its clinical subtypes Y Okada, B Han, LC Tsoi, PE Stuart, E Ellinghaus, T Tejasvi, V Chandran, ... The American Journal of Human Genetics 95 (2), 162-172, 2014 | 235 | 2014 |
Enhanced meta-analysis and replication studies identify five new psoriasis susceptibility loci LC Tsoi, SL Spain, E Ellinghaus, PE Stuart, F Capon, J Knight, T Tejasvi, ... Nature communications 6 (1), 7001, 2015 | 215 | 2015 |
Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases TL Lenz, AJ Deutsch, B Han, X Hu, Y Okada, S Eyre, M Knapp, ... Nature genetics 47 (9), 1085-1090, 2015 | 212 | 2015 |
High-density genotyping study identifies four new susceptibility loci for atopic dermatitis D Ellinghaus, H Baurecht, J Esparza-Gordillo, E Rodríguez, A Matanovic, ... Nature genetics 45 (7), 808-812, 2013 | 212 | 2013 |
Evidence of a causal relationship between body mass index and psoriasis: A mendelian randomization study A Budu-Aggrey, B Brumpton, J Tyrrell, S Watkins, EH Modalsli, ... PLoS medicine 16 (1), e1002739, 2019 | 208 | 2019 |
Photosensitivity and type I IFN responses in cutaneous lupus are driven by epidermal-derived interferon kappa MK Sarkar, GA Hile, LC Tsoi, X Xing, J Liu, Y Liang, CC Berthier, ... Annals of the rheumatic diseases 77 (11), 1653-1664, 2018 | 206 | 2018 |
Genetic correlations among psychiatric and immune‐related phenotypes based on genome‐wide association data DS Tylee, J Sun, JL Hess, MA Tahir, E Sharma, R Malik, BB Worrall, ... American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 177 …, 2018 | 203 | 2018 |
Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms H Baurecht, M Hotze, S Brand, C Büning, P Cormican, A Corvin, ... The American Journal of Human Genetics 96 (1), 104-120, 2015 | 196 | 2015 |
Second-strand synthesis-based massively parallel scRNA-seq reveals cellular states and molecular features of human inflammatory skin pathologies TK Hughes, MH Wadsworth, TM Gierahn, T Do, D Weiss, PR Andrade, ... Immunity 53 (4), 878-894. e7, 2020 | 191 | 2020 |
Investigating the causal relationship of C-reactive protein with 32 complex somatic and psychiatric outcomes: a large-scale cross-consortium Mendelian randomization study BP Prins, A Abbasi, A Wong, A Vaez, I Nolte, N Franceschini, PE Stuart, ... PLoS medicine 13 (6), e1001976, 2016 | 182 | 2016 |
Cytokinocytes: the diverse contribution of keratinocytes to immune responses in skin Y Jiang, LC Tsoi, AC Billi, NL Ward, PW Harms, C Zeng, E Maverakis, ... JCI insight 5 (20), 2020 | 172 | 2020 |
Assessing mitochondrial DNA variation and copy number in lymphocytes of~ 2,000 Sardinians using tailored sequencing analysis tools J Ding, C Sidore, TJ Butler, MK Wing, Y Qian, O Meirelles, F Busonero, ... PLoS genetics 11 (7), e1005306, 2015 | 165 | 2015 |
Identification of functional and expression polymorphisms associated with risk for antineutrophil cytoplasmic autoantibody–associated vasculitis PA Merkel, G Xie, PA Monach, X Ji, DJ Ciavatta, J Byun, BD Pinder, ... Arthritis & rheumatology 69 (5), 1054-1066, 2017 | 162 | 2017 |