Genomic imprinting and physiological processes in mammals V Tucci, AR Isles, G Kelsey, AC Ferguson-Smith, MS Bartolomei, ... Cell 176 (5), 952-965, 2019 | 471 | 2019 |
Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead WH Goodson III, L Lowe, DO Carpenter, M Gilbertson, A Manaf Ali, ... Carcinogenesis 36 (Suppl_1), S254-S296, 2015 | 352 | 2015 |
Distinct physiological and behavioural functions for parental alleles of imprinted Grb10 AS Garfield, M Cowley, FM Smith, K Moorwood, JE Stewart-Cox, K Gilroy, ... Nature 469 (7331), 534-538, 2011 | 239 | 2011 |
Frequent long-range epigenetic silencing of protocadherin gene clusters on chromosome 5q31 in Wilms' tumor AR Dallosso, AL Hancock, M Szemes, K Moorwood, L Chilukamarri, ... PLoS genetics 5 (11), e1000745, 2009 | 177 | 2009 |
High basal γH2AX levels sustain self-renewal of mouse embryonic and induced pluripotent stem cells V Turinetto, L Orlando, Y Sanchez-Ripoll, B Kumpfmueller, MP Storm, ... stem cells 30 (7), 1414-1423, 2012 | 95 | 2012 |
Alternately spliced WT1 antisense transcripts interact with WT1 sense RNA and show epigenetic and splicing defects in cancer AR Dallosso, AL Hancock, S Malik, A Salpekar, L King-Underwood, ... Rna 13 (12), 2287-2299, 2007 | 92 | 2007 |
The role of scaffold proteins in JNK signalling W Engström, A Ward, K Moorwood Cell proliferation 43 (1), 56-66, 2010 | 85 | 2010 |
Identification of differential methylation of the WT1 antisense regulatory region and relaxation of imprinting in Wilms’ tumor K Malik, A Salpekar, A Hancock, K Moorwood, S Jackson, A Charles, ... Cancer research 60 (9), 2356-2360, 2000 | 78 | 2000 |
Developmental Programming Mediated by Complementary Roles of Imprinted Grb10 in Mother and Pup M Cowley, AS Garfield, M Madon-Simon, M Charalambous, RW Clarkson, ... PLoS biology 12 (2), e1001799, 2014 | 59 | 2014 |
Antisense WT1 transcription parallels sense mRNA and protein expression in fetal kidney and can elevate protein levels in vitro K Moorwood, AK Charles, A Salpekar, JI Wallace, KW Brown, K Malik The Journal of Pathology: A Journal of the Pathological Society of Great …, 1998 | 56 | 1998 |
A CTCF-binding silencer regulates the imprinted genes AWT1 and WT1-AS and exhibits sequential epigenetic defects during Wilms' tumourigenesis AL Hancock, KW Brown, K Moorwood, H Moon, C Holmgren, SH Mardikar, ... Human molecular genetics 16 (3), 343-354, 2007 | 48 | 2007 |
The potential for chemical mixtures from the environment to enable the cancer hallmark of sustained proliferative signalling W Engström, P Darbre, S Eriksson, L Gulliver, T Hultman, MV Karamouzis, ... Carcinogenesis 36 (Suppl_1), S38-S60, 2015 | 46 | 2015 |
Antagonistic roles in fetal development and adult physiology for the oppositely imprinted Grb10 and Dlk1genes M Madon-Simon, M Cowley, AS Garfield, K Moorwood, SR Bauer, A Ward BMC biology 12, 1-23, 2014 | 33 | 2014 |
Detailed analysis of paternal knockout Grb10 mice suggests effects on stability of social behavior, rather than social dominance KDA Rienecker, AT Chavasse, K Moorwood, A Ward, AR Isles Genes, Brain and Behavior 19 (1), e12571, 2020 | 21 | 2020 |
Nephropathy and defective spermatogenesis in mice transgenic for a single isoform of the Wilms' tumour suppressor protein, WT1− KTS, together with one disrupted Wt1 Allele D Lahiri, JR Dutton, A Duarte, K Moorwood, CF Graham, A Ward Molecular Reproduction and Development: Incorporating Gamete Research 74 (3 …, 2007 | 18 | 2007 |
Transactivation of the WT1 antisense promoter is unique to the WT1 [+/−] isoform K Moorwood, A Salpekar, SM Ivins, J Hall, RM Powlesland, KW Brown, ... FEBS letters 456 (1), 131-136, 1999 | 13 | 1999 |
Imprinted Grb10, encoding growth factor receptor bound protein 10, regulates fetal growth independently of the insulin-like growth factor type 1 receptor (Igf1r) and insulin … K Moorwood, FM Smith, AS Garfield, A Ward BMC biology 22 (1), 127, 2024 | 1 | 2024 |
Grb7, Grb10 and Grb14, encoding the growth factor receptor-bound 7 family of signalling adaptor proteins have overlapping functions in the regulation of fetal … K Moorwood, FM Smith, AS Garfield, M Cowley, LJ Holt, RJ Daly, A Ward BMC biology 22 (1), 221, 2024 | | 2024 |
Mice carrying paternal knockout of imprinted Grb10 do not show compulsive behaviours KDA Rienecker, AT Chavasse, K Moorwood, A Ward, T Humby, AR Isles bioRxiv, 2020.04. 03.016014, 2020 | | 2020 |
Detailed analysis of paternal knockout Grb10 mice suggests effects on social stability, rather than social dominance KDA Rienecker, AT Chavasse, K Moorwood, A Ward, AR Isles bioRxiv, 493692, 2018 | | 2018 |