β-arrestins and cell signaling SM DeWire, S Ahn, RJ Lefkowitz, SK Shenoy Annu. Rev. Physiol. 69 (1), 483-510, 2007 | 1749 | 2007 |
Independent β-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2 H Wei, S Ahn, SK Shenoy, SS Karnik, L Hunyady, LM Luttrell, ... Proceedings of the National Academy of Sciences 100 (19), 10782-10787, 2003 | 836 | 2003 |
Distinct Phosphorylation Sites on the β2-Adrenergic Receptor Establish a Barcode That Encodes Differential Functions of β-Arrestin KN Nobles, K Xiao, S Ahn, AK Shukla, CM Lam, S Rajagopal, ... Science signaling 4 (185), ra51-ra51, 2011 | 714 | 2011 |
A unique mechanism of β-blocker action: carvedilol stimulates β-arrestin signaling JW Wisler, SM DeWire, EJ Whalen, JD Violin, MT Drake, S Ahn, ... Proceedings of the National Academy of Sciences 104 (42), 16657-16662, 2007 | 699 | 2007 |
Essential role for G protein-coupled receptor endocytosis in the activation of mitogen-activated protein kinase Y Daaka, LM Luttrell, S Ahn, GJ Della Rocca, SSG Ferguson, MG Caron, ... Journal of Biological Chemistry 273 (2), 685-688, 1998 | 697 | 1998 |
Molecular mechanism of β-arrestin-biased agonism at seven-transmembrane receptors E Reiter, S Ahn, AK Shukla, RJ Lefkowitz Annual review of pharmacology and toxicology 52 (1), 179-197, 2012 | 694 | 2012 |
β-arrestin-but not G protein-mediated signaling by the “decoy” receptor CXCR7 S Rajagopal, J Kim, S Ahn, S Craig, CM Lam, NP Gerard, C Gerard, ... Proceedings of the National Academy of Sciences 107 (2), 628-632, 2010 | 689 | 2010 |
Differential kinetic and spatial patterns of β-arrestin and G protein-mediated ERK activation by the angiotensin II receptor S Ahn, SK Shenoy, H Wei, RJ Lefkowitz Journal of Biological Chemistry 279 (34), 35518-35525, 2004 | 664 | 2004 |
Distinct β-arrestin-and G protein-dependent pathways for parathyroid hormone receptor-stimulated ERK1/2 activation D Gesty-Palmer, M Chen, E Reiter, S Ahn, CD Nelson, S Wang, ... Journal of Biological Chemistry 281 (16), 10856-10864, 2006 | 542 | 2006 |
The β2-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor S Maudsley, KL Pierce, AM Zamah, WE Miller, S Ahn, Y Daaka, ... Journal of Biological Chemistry 275 (13), 9572-9580, 2000 | 529 | 2000 |
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1 MR Hara, JJ Kovacs, EJ Whalen, S Rajagopal, RT Strachan, W Grant, ... Nature 477 (7364), 349-353, 2011 | 489 | 2011 |
Dishevelled 2 recruits ß-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4 W Chen, D ten Berge, J Brown, S Ahn, LA Hu, WE Miller, MG Caron, ... Science 301 (5638), 1391-1394, 2003 | 451 | 2003 |
Functional antagonism of different G protein-coupled receptor kinases for β-arrestin-mediated angiotensin II receptor signaling J Kim, S Ahn, XR Ren, EJ Whalen, E Reiter, H Wei, RJ Lefkowitz Proceedings of the National Academy of Sciences 102 (5), 1442-1447, 2005 | 449 | 2005 |
Different G protein-coupled receptor kinases govern G protein and β-arrestin-mediated signaling of V2 vasopressin receptor XR Ren, E Reiter, S Ahn, J Kim, W Chen, RJ Lefkowitz Proceedings of the National Academy of Sciences 102 (5), 1448-1453, 2005 | 423 | 2005 |
Quantifying ligand bias at seven-transmembrane receptors S Rajagopal, S Ahn, DH Rominger, W Gowen-MacDonald, CM Lam, ... Molecular pharmacology 80 (3), 367-377, 2011 | 421 | 2011 |
Src-mediated tyrosine phosphorylation of dynamin is required for β2-adrenergic receptor internalization and mitogen-activated protein kinase signaling S Ahn, S Maudsley, LM Luttrell, RJ Lefkowitz, Y Daaka Journal of Biological Chemistry 274 (3), 1185-1188, 1999 | 363 | 1999 |
Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation DP Staus, RT Strachan, A Manglik, B Pani, AW Kahsai, TH Kim, ... Nature 535 (7612), 448-452, 2016 | 339 | 2016 |
Desensitization, internalization, and signaling functions of β-arrestins demonstrated by RNA interference S Ahn, CD Nelson, TR Garrison, WE Miller, RJ Lefkowitz Proceedings of the National Academy of Sciences 100 (4), 1740-1744, 2003 | 307 | 2003 |
Multiple ligand-specific conformations of the β2-adrenergic receptor AW Kahsai, K Xiao, S Rajagopal, S Ahn, AK Shukla, J Sun, TG Oas, ... Nature chemical biology 7 (10), 692-700, 2011 | 296 | 2011 |
β-arrestin1 interacts with the catalytic domain of the tyrosine kinase c-SRC: role of β-arrestin1-dependent targeting of c-SRC in receptor endocytosis WE Miller, S Maudsley, S Ahn, KD Khan, LM Luttrell, RJ Lefkowitz Journal of Biological Chemistry 275 (15), 11312-11319, 2000 | 273 | 2000 |