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Seungkirl Ahn
Seungkirl Ahn
Assistant Professor of Medicine, Duke University School of Medicine
在 duke.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
β-arrestins and cell signaling
SM DeWire, S Ahn, RJ Lefkowitz, SK Shenoy
Annu. Rev. Physiol. 69 (1), 483-510, 2007
17492007
Independent β-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2
H Wei, S Ahn, SK Shenoy, SS Karnik, L Hunyady, LM Luttrell, ...
Proceedings of the National Academy of Sciences 100 (19), 10782-10787, 2003
8362003
Distinct Phosphorylation Sites on the β2-Adrenergic Receptor Establish a Barcode That Encodes Differential Functions of β-Arrestin
KN Nobles, K Xiao, S Ahn, AK Shukla, CM Lam, S Rajagopal, ...
Science signaling 4 (185), ra51-ra51, 2011
7142011
A unique mechanism of β-blocker action: carvedilol stimulates β-arrestin signaling
JW Wisler, SM DeWire, EJ Whalen, JD Violin, MT Drake, S Ahn, ...
Proceedings of the National Academy of Sciences 104 (42), 16657-16662, 2007
6992007
Essential role for G protein-coupled receptor endocytosis in the activation of mitogen-activated protein kinase
Y Daaka, LM Luttrell, S Ahn, GJ Della Rocca, SSG Ferguson, MG Caron, ...
Journal of Biological Chemistry 273 (2), 685-688, 1998
6971998
Molecular mechanism of β-arrestin-biased agonism at seven-transmembrane receptors
E Reiter, S Ahn, AK Shukla, RJ Lefkowitz
Annual review of pharmacology and toxicology 52 (1), 179-197, 2012
6942012
β-arrestin-but not G protein-mediated signaling by the “decoy” receptor CXCR7
S Rajagopal, J Kim, S Ahn, S Craig, CM Lam, NP Gerard, C Gerard, ...
Proceedings of the National Academy of Sciences 107 (2), 628-632, 2010
6892010
Differential kinetic and spatial patterns of β-arrestin and G protein-mediated ERK activation by the angiotensin II receptor
S Ahn, SK Shenoy, H Wei, RJ Lefkowitz
Journal of Biological Chemistry 279 (34), 35518-35525, 2004
6642004
Distinct β-arrestin-and G protein-dependent pathways for parathyroid hormone receptor-stimulated ERK1/2 activation
D Gesty-Palmer, M Chen, E Reiter, S Ahn, CD Nelson, S Wang, ...
Journal of Biological Chemistry 281 (16), 10856-10864, 2006
5422006
The β2-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor
S Maudsley, KL Pierce, AM Zamah, WE Miller, S Ahn, Y Daaka, ...
Journal of Biological Chemistry 275 (13), 9572-9580, 2000
5292000
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1
MR Hara, JJ Kovacs, EJ Whalen, S Rajagopal, RT Strachan, W Grant, ...
Nature 477 (7364), 349-353, 2011
4892011
Dishevelled 2 recruits ß-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4
W Chen, D ten Berge, J Brown, S Ahn, LA Hu, WE Miller, MG Caron, ...
Science 301 (5638), 1391-1394, 2003
4512003
Functional antagonism of different G protein-coupled receptor kinases for β-arrestin-mediated angiotensin II receptor signaling
J Kim, S Ahn, XR Ren, EJ Whalen, E Reiter, H Wei, RJ Lefkowitz
Proceedings of the National Academy of Sciences 102 (5), 1442-1447, 2005
4492005
Different G protein-coupled receptor kinases govern G protein and β-arrestin-mediated signaling of V2 vasopressin receptor
XR Ren, E Reiter, S Ahn, J Kim, W Chen, RJ Lefkowitz
Proceedings of the National Academy of Sciences 102 (5), 1448-1453, 2005
4232005
Quantifying ligand bias at seven-transmembrane receptors
S Rajagopal, S Ahn, DH Rominger, W Gowen-MacDonald, CM Lam, ...
Molecular pharmacology 80 (3), 367-377, 2011
4212011
Src-mediated tyrosine phosphorylation of dynamin is required for β2-adrenergic receptor internalization and mitogen-activated protein kinase signaling
S Ahn, S Maudsley, LM Luttrell, RJ Lefkowitz, Y Daaka
Journal of Biological Chemistry 274 (3), 1185-1188, 1999
3631999
Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation
DP Staus, RT Strachan, A Manglik, B Pani, AW Kahsai, TH Kim, ...
Nature 535 (7612), 448-452, 2016
3392016
Desensitization, internalization, and signaling functions of β-arrestins demonstrated by RNA interference
S Ahn, CD Nelson, TR Garrison, WE Miller, RJ Lefkowitz
Proceedings of the National Academy of Sciences 100 (4), 1740-1744, 2003
3072003
Multiple ligand-specific conformations of the β2-adrenergic receptor
AW Kahsai, K Xiao, S Rajagopal, S Ahn, AK Shukla, J Sun, TG Oas, ...
Nature chemical biology 7 (10), 692-700, 2011
2962011
β-arrestin1 interacts with the catalytic domain of the tyrosine kinase c-SRC: role of β-arrestin1-dependent targeting of c-SRC in receptor endocytosis
WE Miller, S Maudsley, S Ahn, KD Khan, LM Luttrell, RJ Lefkowitz
Journal of Biological Chemistry 275 (15), 11312-11319, 2000
2732000
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