Impaired enolase 1 glycolytic activity restrains effector functions of tumor-infiltrating CD8+ T cells LF Gemta, PJ Siska, ME Nelson, X Gao, X Liu, JW Locasale, H Yagita, ... Science Immunology 4 (31), eaap9520, 2019 | 119 | 2019 |
Genetic inhibition of hepatic acetyl-CoA carboxylase activity increases liver fat and alters global protein acetylation JDY Chow, RT Lawrence, ME Healy, JE Dominy, JA Liao, DS Breen, ... Molecular metabolism 3 (4), 419-431, 2014 | 119 | 2014 |
Metabolic vulnerabilities in endometrial cancer FL Byrne, IKH Poon, SC Modesitt, JL Tomsig, JDY Chow, ME Healy, ... Cancer research 74 (20), 5832-5845, 2014 | 114 | 2014 |
Comparison of responses of base-specific Salmonella tester strains with the traditional strains for identifying mutagens: the results of a validation study P Gee, CH Sommers, AS Melick, XM Gidrol, MD Todd, RB Burris, ... Mutation Research/Genetic Toxicology and Environmental Mutagenesis 412 (2 …, 1998 | 105 | 1998 |
Aerobic exercise training adaptations are increased by postexercise carbohydrate‐protein supplementation L Ferguson-Stegall, E McCleave, Z Ding, PG Doerner III, Y Liu, B Wang, ... Journal of nutrition and metabolism 2011 (1), 623182, 2011 | 101 | 2011 |
High dietary fat and sucrose result in an extensive and time-dependent deterioration in health of multiple physiological systems in mice JG Burchfield, MA Kebede, CC Meoli, J Stöckli, PT Whitworth, AL Wright, ... Journal of biological chemistry 293 (15), 5731-5745, 2018 | 87 | 2018 |
Inhibition of hepatic lipogenesis enhances liver tumorigenesis by increasing antioxidant defence and promoting cell survival ME Nelson, S Lahiri, JDY Chow, FL Byrne, SR Hargett, DS Breen, ... Nature Communications 8 (1), 14689, 2017 | 81 | 2017 |
Dietary effects on liver tumor burden in mice treated with the hepatocellular carcinogen diethylnitrosamine ME Healy, JDY Chow, FL Byrne, DS Breen, N Leitinger, C Li, C Lackner, ... Journal of hepatology 62 (3), 599-606, 2015 | 75 | 2015 |
Dynamic metabolomics reveals that insulin primes the adipocyte for glucose metabolism JR Krycer, K Yugi, A Hirayama, DJ Fazakerley, LE Quek, R Scalzo, ... Cell reports 21 (12), 3536-3547, 2017 | 62 | 2017 |
Phosphoproteomics reveals conserved exercise‐stimulated signaling and AMPK regulation of store‐operated calcium entry ME Nelson, BL Parker, JG Burchfield, NJ Hoffman, EJ Needham, ... The EMBO journal 38 (24), e102578, 2019 | 56 | 2019 |
Insulin signaling requires glucose to promote lipid anabolism in adipocytes JR Krycer, LE Quek, D Francis, A Zadoorian, FC Weiss, KC Cooke, ... Journal of Biological Chemistry 295 (38), 13250-13266, 2020 | 46 | 2020 |
Dietary sugar intake increases liver tumor incidence in female mice ME Healy, S Lahiri, SR Hargett, JDY Chow, FL Byrne, DS Breen, ... Scientific Reports 6 (1), 22292, 2016 | 39 | 2016 |
Systems-level analysis of insulin action in mouse strains provides insight into tissue-and pathway-specific interactions that drive insulin resistance ME Nelson, S Madsen, KC Cooke, AM Fritzen, IH Thorius, SWC Masson, ... Cell metabolism 34 (2), 227-239. e6, 2022 | 31 | 2022 |
Phenotypic screen for oxygen consumption rate identifies an anti-cancer naphthoquinone that induces mitochondrial oxidative stress FL Byrne, EM Olzomer, GR Marriott, LE Quek, A Katen, J Su, ME Nelson, ... Redox biology 28, 101374, 2020 | 15 | 2020 |
Lysophosphatidic acid counteracts glucagon-induced hepatocyte glucose production via STAT3 EP Taddeo, SR Hargett, S Lahiri, ME Nelson, JA Liao, C Li, ... Scientific reports 7 (1), 127, 2017 | 9 | 2017 |
SMaSH: A scalable, general marker gene identification framework for single-cell RNA sequencing and Spatial Transcriptomics ME Nelson, SG Riva, A Cvejic bioRxiv, 2021.04. 08.438978, 2021 | 8 | 2021 |
Phosphoproteomics reveals conserved exercise‐stimulated signaling and AMPK regulation of store‐operated calcium entry ME Nelson, BL Parker, JG Burchfield, NJ Hoffman, EJ Needham, ... The EMBO Journal 39 (8), e104246, 2020 | 7 | 2020 |
Insulin Tolerance Test under Anaesthesia to Measure Tissue-specific Insulin-stimulated Glucose Disposal DJ Fazakerly, AM Fritzen, ME Nelson, IH Thorius, KC Cooke, ... BioProtocol 9 (2), 2019 | 7 | 2019 |
A gas trapping method for high-throughput metabolic experiments JR Krycer, C Diskin, ME Nelson, XY Zeng, DJ Fazakerley, DE James BioTechniques 64 (1), 27-29, 2018 | 7 | 2018 |
Deep proteome profiling of white adipose tissue reveals marked conservation and distinct features between different anatomical depots S Madsen, ME Nelson, V Deshpande, SJ Humphrey, KC Cooke, A Howell, ... Molecular & Cellular Proteomics 22 (3), 2023 | 6 | 2023 |