Active site specificity profiling of the matrix metalloproteinase family: Proteomic identification of 4300 cleavage sites by nine MMPs explored with structural and synthetic … U Eckhard, PF Huesgen, O Schilling, CL Bellac, GS Butler, JH Cox, ... Matrix Biology 49, 37-60, 2016 | 214 | 2016 |
Proteome-wide analysis of protein carboxy termini: C terminomics O Schilling, O Barré, PF Huesgen, CM Overall Nature methods 7 (7), 508-511, 2010 | 163 | 2010 |
LysargiNase mirrors trypsin for protein C-terminal and methylation-site identification PF Huesgen, PF Lange, LD Rogers, N Solis, U Eckhard, O Kleifeld, ... Nature methods 12 (1), 55-58, 2015 | 156 | 2015 |
Characterization of the prime and non-prime active site specificities of proteases by proteome-derived peptide libraries and tandem mass spectrometry O Schilling, PF Huesgen, O Barré, U auf dem Keller, CM Overall Nature protocols 6 (1), 111-120, 2011 | 123* | 2011 |
Dual specificities of the glyoxysomal/peroxisomal processing protease Deg15 in higher plants M Helm, C Lück, J Prestele, G Hierl, PF Huesgen, T Fröhlich, GJ Arnold, ... Proceedings of the National Academy of Sciences 104 (27), 11501-11506, 2007 | 121 | 2007 |
Annotating N termini for the Human Proteome Project: N termini and Nα-acetylation status differentiate stable cleaved protein species from degradation remnants in the human … PF Lange, PF Huesgen, K Nguyen, CM Overall Journal of proteome research 13 (4), 2028-2044, 2014 | 109 | 2014 |
Proteomic protease specificity profiling of clostridial collagenases reveals their intrinsic nature as dedicated degraders of collagen U Eckhard, PF Huesgen, H Brandstetter, CM Overall Journal of proteomics 100, 102-114, 2014 | 99 | 2014 |
The family of Deg proteases in cyanobacteria and chloroplasts of higher plants PF Huesgen, H Schuhmann, I Adamska Physiologia Plantarum 123 (4), 413-420, 2005 | 99 | 2005 |
The DEG15 serine protease cleaves peroxisomal targeting signal 2-containing proteins in Arabidopsis H Schuhmann, PF Huesgen, C Gietl, I Adamska Plant physiology 148 (4), 1847-1856, 2008 | 97 | 2008 |
Photodamaged D1 protein is degraded in Arabidopsis mutants lacking the Deg2 protease PF Huesgen, H Schuhmann, I Adamska FEBS letters 580 (30), 6929-6932, 2006 | 87 | 2006 |
Proteolysis of cystatin C by cathepsin D in the breast cancer microenvironment. V Laurent-Matha, P Huesgen, O Masson, D Derocq, C Prébois, ... FASEB Journal 26 (12), 5172-81, 2012 | 83 | 2012 |
Sensitive determination of proteolytic proteoforms in limited microscale proteome samples SSH Weng, F Demir, EK Ergin, S Dirnberger, A Uzozie, D Tuscher, ... Molecular & Cellular Proteomics 18 (11), 2335-2347, 2019 | 82 | 2019 |
Deg/HtrA proteases as components of a network for photosystem II quality control in chloroplasts and cyanobacteria PF Huesgen, H Schuhmann, I Adamska Research in microbiology 160 (9), 726-732, 2009 | 73 | 2009 |
Dual function of a secreted fungalysin metalloprotease in Ustilago maydis B Ökmen, B Kemmerich, D Hilbig, R Wemhöner, J Aschenbroich, A Perrar, ... New Phytologist 220 (1), 249-261, 2018 | 71 | 2018 |
Structure of the Mycosin-1 Protease from the Mycobacterial ESX-1 Protein Type VII Secretion System M Solomonson, PF Huesgen, GA Wasney, N Watanabe, RJ Gruninger, ... Journal of Biological Chemistry 288 (24), 17782-17790, 2013 | 68 | 2013 |
The proteome microenvironment determines the protective effect of preconditioning in cisplatin-induced acute kidney injury MR Späth, MP Bartram, N Palacio-Escat, KJR Hoyer, C Debes, F Demir, ... Kidney international 95 (2), 333-349, 2019 | 64 | 2019 |
A fungal substrate mimicking molecule suppresses plant immunity via an inter-kingdom conserved motif JCM Villamil, AN Mueller, F Demir, U Meyer, B Ökmen, JS Hüynck, ... Nature Communications 10 (1), 1576, 2019 | 63 | 2019 |
N‐and C‐terminal degradomics: new approaches to reveal biological roles for plant proteases from substrate identification PF Huesgen, CM Overall Physiologia plantarum 145 (1), 5-17, 2012 | 61 | 2012 |
TopFIND 2.0—linking protein termini with proteolytic processing and modifications altering protein function PF Lange, PF Huesgen, CM Overall Nucleic Acids Research 40 (D1), D351-D361, 2012 | 58 | 2012 |
Proteomic amino-termini profiling reveals targeting information for protein import into complex plastids PF Huesgen, M Alami, PF Lange, LJ Foster, WP Schröder, CM Overall, ... PloS one 8 (9), e74483, 2013 | 55 | 2013 |