Free radical-mediated oxidative DNA damage in the mechanism of thalidomide teratogenicity T Parman, MJ Wiley, PG Wells Nature medicine 5 (5), 582-585, 1999 | 569 | 1999 |
Oxidative stress in developmental origins of disease: teratogenesis, neurodevelopmental deficits, and cancer PG Wells, GP McCallum, CS Chen, JT Henderson, CJJ Lee, J Perstin, ... Toxicological sciences 108 (1), 4-18, 2009 | 545 | 2009 |
Glucuronidation and the UDP-glucuronosyltransferases in health and disease PG Wells, PI Mackenzie, JR Chowdhury, C Guillemette, PA Gregory, ... Drug metabolism and disposition 32 (3), 281-290, 2004 | 323 | 2004 |
Oxidative damage in chemical teratogenesis PG Wells, PM Kim, RR Laposa, CJ Nicol, T Parmana, LM Winn Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 396 (1 …, 1997 | 308 | 1997 |
A teratologic suppressor role for p53 in benzo(a)pyrene–treated transgenic p53-deficient mice CJ Nicol, ML Harrison, RR Laposa, IL Gimelshtein, PG Wells Nature genetics 10 (2), 181-187, 1995 | 283 | 1995 |
Molecular and biochemical mechanisms in teratogenesis involving reactive oxygen species PG Wells, Y Bhuller, CS Chen, W Jeng, S Kasapinovic, JC Kennedy, ... Toxicology and applied pharmacology 207 (2), 354-366, 2005 | 277 | 2005 |
An embryoprotective role for glucose-6-phosphate dehydrogenase in developmental oxidative stress and chemical teratogenesis CJ Nicol, J Zielenski, LC Tsui, PG Wells Proceedings of the Korea Environmental Mutagen Society Conference, 48-64, 2002 | 224 | 2002 |
Decreased glucuronidation and increased bioactivation of acetaminophen in Gilbert's syndrome SMF De Morais, JP Uetrecht, PG Wells Gastroenterology 102 (2), 577-586, 1992 | 206 | 1992 |
Biochemical toxicology of chemical teratogenesis PG Wells, LM Winn Critical reviews in biochemistry and molecular biology 31 (1), 1-40, 1996 | 202 | 1996 |
Effects of fetal antiepileptic drug exposure: outcomes at age 4.5 years KJ Meador, GA Baker, N Browning, MJ Cohen, RL Bromley, ... Neurology 78 (16), 1207-1214, 2012 | 160 | 2012 |
Pregnancy registries in epilepsy: a consensus statement on health outcomes KJ Meador, PB Pennell, CL Harden, JC Gordon, T Tomson, PW Kaplan, ... Neurology 71 (14), 1109-1117, 2008 | 150 | 2008 |
Evidence for embryonic prostaglandin H synthase-catalyzed bioactivation and reactive oxygen species-mediated oxidation of cellular macromolecules in phenytoin and benzo [a … LM Winn, PG Wells Free Radical Biology and Medicine 22 (4), 607-621, 1997 | 135 | 1997 |
Oxidative DNA damage and repair in teratogenesis and neurodevelopmental deficits PG Wells, GP McCallum, KCH Lam, JT Henderson, SL Ondovcik Birth Defects Research Part C: Embryo Today: Reviews 90 (2), 103-109, 2010 | 124 | 2010 |
Maternal administration of superoxide dismutase and catalase in phenytoin teratogenicity1 LM Winn, PG Wells Free Radical Biology and Medicine 26 (3-4), 266-274, 1999 | 121 | 1999 |
Phenytoin-initiated DNA oxidation in murine embryo culture, and embryo protection by the antioxidative enzymes superoxide dismutase and catalase: evidence for reactive oxygen … LM Winn, PG Wells Molecular pharmacology 48 (1), 112-120, 1995 | 111 | 1995 |
Free radical intermediates of phenytoin and related teratogens: prostaglandin H synthase-catalyzed bioactivation, electron paramagnetic resonance spectrometry, and … T Parman, G Chen, PG Wells Journal of Biological Chemistry 273 (39), 25079-25088, 1998 | 106 | 1998 |
In vitro bioactivation of phenytoin to a reactive free radical intermediate by prostaglandin synthetase, horseradish peroxidase, and thyroid peroxidase. S Kubow, PG Wells Molecular pharmacology 35 (4), 504-511, 1989 | 98 | 1989 |
Oxoguanine glycosylase 1 protects against methamphetamine-enhanced fetal brain oxidative DNA damage and neurodevelopmental deficits AW Wong, GP McCallum, W Jeng, PG Wells Journal of Neuroscience 28 (36), 9047-9054, 2008 | 97 | 2008 |
Oxidative stress and thiol depletion in plasma and peripheral blood lymphocytes from HIV-infected patients: toxicological and pathological implications SL Walmsley, LM Winn, ML Harrison, JP Uetrecht, PG Wells Aids 11 (14), 1689-1697, 1997 | 90 | 1997 |
Methamphetamine-enhanced embryonic oxidative DNA damage and neurodevelopmental deficits W Jeng, AW Wong, R Ting-A-Kee, PG Wells Free Radical Biology and Medicine 39 (3), 317-326, 2005 | 86 | 2005 |